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Saposins Pages on BioPortfolio:
BioPortfolio - PSAP - prosaposin (variant Gaucher disease and ...
16823039, determination of crystal structure of human saposins A and C to 2.0 Angstroms and 2.4 Angstroms, respectively and both reveal the compact, ...
http://www.bioportfolio.com/gene/5660-PSAP.html...
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BioPortfolio - Saposins
Saposins - BioPortfolio - Indepth. ... Crystal structures of human saposins C andD: implications for lipid recognition and membrane interactions. ...
http://www.bioportfolio.com/indepth/Saposins.html...
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BioPortfolio - AT3G51730
At3g51730 saposin B domain-containing protein. At3g52800 zinc finger (AN1-like) family protein. At3g55430 glycosyl hydrolase family 17 protein / beta-1 . ...
http://www.bioportfolio.com/search/AT3G51730.html...
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BioPortfolio - S2P - S2P
S2P Antibody / S2P Antibodies · Sam50 Antibody / Sam50 Antibodies · saposin Antibody / saposin Antibodies · sarcosine dehydrogenase Antibody / sarcosine .
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http://www.bioportfolio.com/gene/36262-S2P.html...
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BioPortfolio - Glucosylceramidase
Neurological deficits and glycosphingolipid accumulation in saposin B deficient ... Saposin B derives from the multi-functional precursor, prosaposin, and. ...
http://www.bioportfolio.com/indepth/Glucosylceramidase.html...
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BioPortfolio - CD1B - CD1b molecule
14716313, model proposed in which saposin C exposes lipid antigens from intralysosomal membranes for loading onto CD1b ...
http://www.bioportfolio.com/gene/910-CD1B.html...
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BioPortfolio - cnpy1 - canopy1
Publication Link, Summary of findings. 16488878, saposin-related protein, expressed specifically in the midbrain-hindbrain boundary of zebrafish embryos
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http://www.bioportfolio.com/gene/402819-cnpy1.html...
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BioPortfolio - Sphingolipid Activator Proteins patents
7378231, Diagnosis of lysosomal storage disorders using saposins and other ... 7166691, Saposin C and receptors as targets for treatment of benign and ...
http://www.bioportfolio.com/indepth/Sphingolipid_Activator_P...
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BioPortfolio - beta-2-microglobulin molecules
17372201, saposin B may facilitate lipid binding to CD1d molecules ... of Asn-42 affects stability of the CD1d heavy chain beta 2-microglobulin heterodimer. ...
http://www.bioportfolio.com/search/beta-2-microglobulin_mole...
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BioPortfolio - CG3911
CG12070, Saposin-r, ++, +++ ... http://www.nature.com/ncb/journal/v8/n8/fig_tab/ ncb1439_T1.h... Trafficking protein particle complex 3, Homo sapiens ...
http://www.bioportfolio.com/search/CG3911.html...
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Results from other life science and pharmaceutical sites:
Effect of saposins on acid sphingomyelinase.
The effect of saposins (A, B, C and D) on acid sphingomyelinase activity was determined using a crude human kidney sphingomyelinase preparation and a ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...
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Crystal structures of saposins A and C. [Protein Sci. 2006 ...
Saposins A and C are sphingolipid activator proteins required for the ... The saposins interact with lipids, leading to an enhanced accessibility of the ...
http://www.ncbi.nlm.nih.gov/pubmed/16823039...
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Saposins facilitate CD1d-restricted presentation of an exogenous ...
We hypothesized that lysosomal saposins, which are cofactors required for sphingolipid degradation, might be involved in this process. ...
http://www.nature.com/ni/journal/v5/n2/full/ni1034.html...
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Storage of saposins A and D in infantile neuronal ...[FEBS Lett ...
Saposins A and D, also known as sphingolipid activator proteins (SAPs), ... This is the first time that saposins have been found to be stored in any form of ...
http://www.ncbi.nlm.nih.gov/pubmed/8370464...
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Acid sphingomyelinase possesses a domain homologous to its ...
By analogy with the known functions of saposins, this sphingomyelinase saposin- type domain may possess lipid-binding and/or sphingomyelinase-activator ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=21...
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Crystal structures of human saposins C andD: impli...[Structure ...
Human saposins are essential proteins required for degradation of sphingolipids and ... We describe two crystal structures of human saposin C in an "open" ...
http://www.ncbi.nlm.nih.gov/pubmed/18462685...
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Crystal structures of saposins A and C
Saposins A and C are sphingolipid activator proteins required for the lysosomal breakdown of galactosylceramide and glucosylceramide, respectively. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=22...
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Interaction of saposins, acidic lipids, and glucos...[J Biol Chem ...
Activity of lysosomal glucosylceramidase is stimulated by two small glycoproteins, saposin A and C, which are, together with two other similar
glycoproteins ...
http://www.ncbi.nlm.nih.gov/pubmed/2298731...
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J3-crystallin of the jellyfish lens: Similarity to saposins
J3-crystallin, one of the three major eye-lens proteins of the cubomedusan jellyfish (Tripedalia cystophora), shows similarity to vertebrate saposins, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=60...
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Differential membrane interactions of saposins A a...[J Biol Chem ...
Three of these saposins (B, C, and D) share common structural features ... Such membrane interactions and orientations of the saposins determine the ...
http://www.ncbi.nlm.nih.gov/pubmed/11356836?dopt=Abstract...
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