Search Results for "Saredutant Succinate"
Original Source: An Eight-week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression
The purpose of the study is to evaluate the efficacy and safety of saredutant (or SR48968C) in patients with depression. The primary objective is to evaluate the efficacy of a 100 mg dose of saredutant compared to placebo in patients with depression. The secondary objectives are to evaluate the safety of saredutant, to evaluate the efficacy of saredutant on disability and quality of life in patients with depression, and to evaluate blood levels of saredutant.
Matching Channels
None
Matching News
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis wi...
Dr. Reddy’s Announces the Launch of Metoprolol Succinate ER (Extended-Release) Tablets
Dr. Reddy’s Laboratories (NYSE: RDY) announced today that is has launched Metoprolol Succinate ER (Extended-Release) Tablets (25 mg, 50 mg, 100 mg & 200 mg), a bioequivalent...
Duchesnay wins US FDA OK for morning sickness drug Diclegis
Duchesnay won the US FDA's approval to market Diclegis (doxylamine succinate 10mg, pyridoxine hydrochloride 10mg) delayed-release tablets as a therapy for nausea and vomiting related to pregnancy in...
Dr. Reddy's unveils high blood pressure tablets in US
Dr. Reddy's Laboratories, an integrated global pharmaceutical company, has introduced Metoprolol Succinate extended-release (ER) tablets of 25mg, 50mg, 100mg and 200mg strengths in the US.
Duchesnay introduces Diclegis in US market
Duchesnay USA has announced the availability of Diclegis, a composition of 10mg doxylamine succinate and 10mg pyridoxine hydrochloride (vitamin B6), in US pharmacies.
Matching PubMed Articles
These experiments were undertaken to assess the mechanisms underlying the antidepressant-like effects of the neurokinin-2 (NK2) receptor antagonist saredutant (SR48968) in rats tested in the forced sw...
Intracerebroventricular (i.c.v.) or intraperitoneal (IP) administration of saredutant (SR48968), an NK2 receptor antagonist, produces anxiolytic-like effects in rodents in a number of animal models of...
Succinic acid is excreted during anaerobiosis by many bacteria, and manifold applications are known making the biotechnological production of succinate attractive. Although the pathways for succinate...
Two new holmium-succinate frameworks have been synthesized by hydrolysis in situ of the succinylsalicylic acid under different hydrothermal conditions. Compound 1, [Ho(2)(C(4)H(4)O(4))(3)(H(2)O)(2)]·...
Succinate production in Escherichia coli.
Succinate has been recognized as an important platform chemical that can be produced from biomass. While a number of organisms are capable of succinate production naturally, this review focuses on the...
