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Search Results for "Seb Pulsed Dendritic Cell"

00:52 EDT 20th June 2013 | BioPortfolio

Original Source: Enhanced anti-tumor immunity by superantigen-pulsed dendritic cells.

Staphylococcal enterotoxins A (SEA) and B (SEB) are classical models of superantigens (SAg), which induce potent T-cell-stimulating activity by forming complexes with MHC class II molecules on antigen-presenting cells. This large-scale activation of T-cells is accompanied by increased production of cytokines such as interferon-γ (IFN-γ). Additionally, as we previously reported, IFN-γ-producing CD8(+) T cells act as "helper cells," supporting the ability of dendritic cells to produce interleukin-12 (IL-12...

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Prostate specific membrane antigen PSMA

Prostate-specific membrane antigen (PSMA) is a transmembrane protein commonly found on the surface of late-stage and metastatic prostate cancer and a well-known imaging biomarker for staging and monit...

Vaccines

A vaccine is any preparation intended to produce immunity to a disease by stimulating the production of antibodies. It creates immunity but does not cause the disease. There are several differnt typ...

Squamous Cell Carcinoma

Squamous cell carcinoma (SCC) is a carcinomatous cancer occurring in many different organs, including the skin, lips, mouth, esophagus, urinary bladder, prostate, lungs, vagina, and cervix. It is a...

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Deciphering the transcriptional network of the dendritic cell lineage

The transcriptional regulation of commitment to the dendritic cell (DC) lineage and functional specialization of DCs in vivo is poorly understood. In this Resource, Merad and colleagues identify the l...

Prima BioMed Awarded Japanese Patent for CVac(TM)

SYDNEY, AUSTRALIA -- (Marketwired) -- 04/17/13 -- Prima BioMed Ltd (ASX: PRR) (NASDAQ: PBMD) (ISIN: US74154B2034) ("Prima", "the Company") is pleased to announce that it has been granted a patent fro...

Pulsed Plasma Characterization

The performance of the Hiden Analytical family of plasma diagnostic tools is further advanced by integration of onboard timers for real-time pulsed plasma measurement, the fast gating controllable wit...

Compensatory dendritic cell development mediated by BATF–IRF interactions

The roles of BATF transcription factors in dendritic cell differentiation are studied, providing evidence for molecular compensation by related family members; compensation is based on the interaction...

IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8+ T cell responses to influenza A virus

Unlike vaccination, infection by a live pathogen often impairs dendritic cell function. Iwasaki and colleagues show that during infection with influenza virus, signaling via the IL-1 receptor is both...

TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells

Dendritic cell production patent is awarded to NW Bio

Northwest Biotherapeutics obtained a U.S. patent for technology involving the production of human dendritic cells.  -More- 

ImmunoCellular adds $21M

ImmunoCellular Therapeutics Ltd. (NYSE-M:IMUC) raised $21 million through the sale of 10 million shares at $2.10 in a follow-on underwritten by Lazard; Roth Capital Partners; Maxim; and Summer Street....

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Dendritic cell-based immunotherapy for colon cancer using an HLA-A*0201-restricted cytotoxic T-lymphocyte epitope from tumor-associated antigen 90K.

Tumor-associated antigen 90K is implicated in cell-cell and cell-extracellular matrix adhesion through its interaction with galectin-3 and integrin-β1 and is highly expressed in malignant tissues, ma...

Type I interferon supports primary CD8(+) T-cell responses to peptide-pulsed dendritic cells in the absence of CD4(+) T-cell help.

CD8(+) T-cell responses to non-pathogen, cell-associated antigens such as minor alloantigens or peptide-pulsed dendritic cells (DC) are usually strongly dependent on help from CD4(+) T cells. However,...

Enhanced anti-tumor immunity by superantigen-pulsed dendritic cells.

Staphylococcal enterotoxins A (SEA) and B (SEB) are classical models of superantigens (SAg), which induce potent T-cell-stimulating activity by forming complexes with MHC class II molecules on antigen...

Effect of double-stranded DNA on maturation of dendritic cells in vitro.

A preparation of human genomic fragmented double-stranded DNA (dsDNA) was used as maturation stimulus in cultures of human dendritic cells (DCs) generated in compliance with the interferon protocol. C...

Monocytes join the dendritic cell family.

Dendritic cells are professional antigen-presenting cells that mediate immunity and tolerance. Cheong et al. (2010) uncover a new route for dendritic cell production in vivo. They show that in respo...

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