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Generics Drugs - news, views, reports

A generic drug (generic drugs, short: generics) is a drug defined as "a drug product that is comparable to brand/reference listed drug product in dosage form, strength, route of administration,...

Singulair

Singulair, the brand name for montelukast sodium, is produced by Merck & Co., Inc. Its annual sales in 2009 were $3m, ranking it 7th in the world. Singulair acts by blocking leukotrienes, to r...

OxyContin

OxyContin, an narcotic analgesic produced by Purdue Pharma LP, nets $3m in sales annually, placing it 8th in the world for annual sales. OxyContin in the brand name for oxycodone, and is similar t...

Lipitor

Lipitor was the best selling drug in 2009, with the 2009 annual sales coming in at over $5m for its company, Pfizer Inc. Lipitor is the brand name for an atorvastatin calcium medication that is pres...

Ibuprofen-Famotidine Combination Reduces Ulcer Risk

Combining ibuprofen and famotidine into 1 pill can control pain while lowering the risk for ulcers posed by ibuprofen alone. Medscape Medical News

SPI Pharma launches Actimask Ibuprofen 92S

SPI Pharma, Inc., a global leader in providing pharmaceutical ingredients and technologies for patient-friendly dosage forms, announces the launch of Actimask Ibuprofen 92S, a taste-masked Ibuprofen.

Altitude Sickness: Does Ibuprofen Prevent or Mask It?

New research suggests a decrease in the incidence of acute mountain sickness with prophylactic ibuprofen use compared with placebo, but the drug may simply be masking underlying headaches. Medscape...

Ibuprofen and naproxen can cause kidney damage in children

Sick children, especially those with some dehydration from flu or other illnesses, risk significant kidney injury if given drugs such as ibuprofen and naproxen, Indiana University School of Medicine r...

Following Bone Surgery Or A Fracture, Ibuprofen Improves Bone Repair

A study conducted at the University of Granada has demonstrated that ibuprofen ­- a non-steroidal anti-inflammatory drug (NSAID)­ - has beneficial effects on bone repair after a fracture or foll...

Exercise-Induced Intestinal Injury by Ibuprofen in Athletes

NSAIDs, such as ibuprofen, are commonly used by athletes for exercise-related pain relief -- but can they cause damaging intestinal effects? Medicine and Science in Sports and Exercise®

Albemarle raises ibuprofen prices by 15%

Albemarle is increasing its prices for the active pharmaceutical ingredient (API) ibuprofen by 15 per cent.

Ibuprofen improves bone repair after surgery or a fracture, study suggests

An in vitro study has demonstrated that a therapeutic dose of the non-steroidal anti-inflammatory drug ibuprofen improves bone repair.

Electrophysiological Correlates of Brand Names.

EEG coherence has been used extensively in the investigation of language processing of different words categories. In contrast, relatively less is known about EEG coherence pattern of processing brand...

Ibuprofen-phospholipid solid dispersions: Improved dissolution and gastric tolerance.

Solid dispersions of ibuprofen with various phospholipids were prepared, and the effect of phospholipids on the in vitro dissolution and in vivo gastrointestinal toxicity of ibuprofen was evaluated. M...

Development of novel ibuprofen-loaded solid dispersion with enhanced bioavailability using cycloamylose.

To develop a novel ibuprofen-loaded solid dispersion with enhanced bioavailability using cycloamylose, it was prepared using spray-drying techniques with cycloamylose at a weight ratio of 1:1. The eff...

Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen.

Summary Background and purpose. Recently, we identified etodolac as a possible ligand for the human intestinal proton-couple peptide transporter (hPEPT1). This raised the possibility that other NSAIDs...

Drug nano-domains in spray-dried ibuprofen-silica microspheres.

Silica microspheres encapsulating ibuprofen in separated domains at the nanometre scale are formed by spray-drying and sol-gel processes. A detailed (1)H and (13)C NMR study of these microspheres show...