Search Results for "Sensory Nerves Schwann Cell From Stem Cells"
Original Source: Nerve repair with adipose-derived stem cells protects dorsal root ganglia neurons from apoptosis.
Novel approaches are required in the clinical management of peripheral nerve injuries because current surgical techniques result in deficient sensory recovery. Microsurgery alone fails to address extensive cell death in the dorsal root ganglia (DRG), in addition to poor axonal regeneration. Incorporation of cultured cells into nerve conduits may offer a novel approach in which to combine nerve repair and enhance axonal regeneration with neuroprotective therapies. We examined apoptotic mediator expression in...
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Stem cells can be found in all multicellular organisms and are characterized by the ability to renew themselves through mitotic cell division and differentiate into a diverse range of specialized ce...
Hematopoietic Stem Cell Transplantation
The Notch signaling pathway has been found to play central roles in humans in stem cell maintenance, cell fate decisions, and in cancer as well. Notch family members are being revealed as oncogenes...
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Bacteria's hidden skill could pave way for stem cell treatments
(University of Edinburgh) A discovery about the way in which bugs spread throughout the body could help to develop stem cell treatments.Researchers at the University of Edinburgh have found that bacte...
Bacteria’s hidden skill could pave way for stem cell treatments
Researchers at the University of Edinburgh have found that bacteria are able to change the make-up of supporting cells within the nerve system, called Schwann cells, so that they take on the propertie...
A role for Schwann cell–derived neuregulin-1 in remyelination
The authors show that nerve injury induces expression of NRG1 type I in Schwann cells and that this expression is necessary for efficient remyelination. In addition, axonally expressed NRG1 type III c...
Pinning down the pain: Schwann cell protein plays major role in neuropathic pain
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, rol...
Bacteria generate stem cells naturally during infection
Leprosy is a bacterial disease that spreads to muscles and other tissues in the body, causing neurodegeneration and muscle weakness. Reprogramming Adult Schwann Cells to Stem Cell-Like Cells by Lepros...
Control of Neuropathic Pain Depends on a Schwann Cell Protein
Pain researchers have found that a protein produced by Schwann cells plays a critical role in controlling allodynia and...
Microbiology: Leprosy bacteria reprogram cells
The bacterium that causes leprosy spreads through the body by reprogramming infected cells to become stem-cell-like cells that can form other cell types.Leprosy is caused by the bacterium Mycobacteriu...
Peripheral Nervous System Damage - Therapy Shows Promise
According to a study published online by the Journal of Neuroscience, researchers have gained new insight into how Schwann cells protect and repair damage caused by trauma and disease. These findings...
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Schwann cells are critically important for tissue repair, axonal regrowth and remyelination following injury to peripheral nerves. The absence of Schwann cells or an equivalent cell type in the centra...
Peroxisome proliferator-activated receptor-γ (PPAR-γ) has been found to play an essential role in cell proliferation, but whether it was involved in Schwann cells differentiation has never been stud...
Generation of Schwann Cell-Derived Multipotent Neurospheres Isolated from Intact Sciatic Nerve.
Schwann cells (SCs) are the supporting cells of the peripheral nervous system and originate from the neural crest. They play a unique role in the regeneration of injured peripheral nerves and have the...
The myelin sheaths that surround the thick axons of the peripheral nervous system are produced by the highly specialized Schwann cells. Differentiation of Schwann cells and myelination occur in discre...
Mesenchymal stem cells are capable of differentiating into Schwann-like cells. In this study, we induced human umbilical-cord mesenchymal stem cells (HUMSCs) in vitro into neurospheres constituted by...
