Search Results for "Sickle Cell Anemia And Renal Transplant"
Original Source: Kidney Transplantation in Patients With Sickle Cell Disease
The purpose of this research is to better characterize the components and mechanisms of the immune systems of persons with sickle cell disease who have had a kidney transplant and are immunosuppressed. If we can improve our scientific understanding of the fundamental mechanisms involved in patient outcomes, we can potentially maximize the benefits that we seek from transplantation in sickle cell patients with end stage renal disease.
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Located under your left lung, beneath the diaphragm, the spleen has two functions; lymphocyte production (which takes place in the white pulp) and filtration of the blood by phagocytes to remove mic...
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Sickle cell anemia: Maps and newborn estimates released
In 2010 around 300,000 babies were born with sickle cell anemia, a serious blood disorder which can be fatal if untreated, and 5.5 million newborns inherited the sickle cell gene, a new study suggests...
Chemotherapy-free stem cell transplant shows promise for sickle cell disease
Two brothers have been cured of their sickle cell disease at the University of Illinois Hospital & Health Sciences System using a relatively uncommon type of stem cell transplant that is performed wit...
Emmaus completes recruitment for Phase III sickle cell anemia therapy trial
Specialty pharmaceutical and regenerative medicine company Emmaus Medical has completed enrolling over 225 patients in the Phase III clinical trial to asses the safety and efficacy of L-glutamine in t...
Chicago woman cured of sickle cell disease
A Chicago woman is the first Midwest patient to receive a successful stem cell transplant to cure her sickle cell disease without chemotherapy in preparation for the transplant.
Bone marrow transplants hold promise for sickle cell patients
Research shows that even partially matched bone marrow transplants are able to eliminate sickle cell disease in some patients with sickle cell anemia.
Midwest patient receives successful stem cell transplant to cure sickle cell disease
Chicagoan Ieshea Thomas is the first Midwest patient to receive a successful stem cell transplant to cure her sickle cell disease without chemotherapy in preparation for the transplant.
Mutation that causes sickle cell anemia may offer new way to treat drug-resistant cancers
The genetic mutation that causes sickle cell anemia also turns red blood cells into potent tumor killers and may offer a new way to treat cancers that are resistant to existing treatments, according t...
Sickle cell disease, sickle cell trait are not the same
(HealthDay)—Both sickle cell disease and the condition known as sickle cell trait are genetic blood diseases: You're born with one or the other because of the genes inherited from your parents. Beyo...
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Free heme and the polymerization of sickle cell hemoglobin.
In search of novel control parameters for the polymerization of sickle cell hemoglobin (HbS), the primary pathogenic event of sickle cell anemia, we explore the role of free heme, which may be excessi...
Many patients with thalassemia have been cured with BMT since the first successful transplant in 1981. Allogeneic stem cell gene therapy is the only treatment option for patients with sickle cell anem...
Chronic blood transfusion (CBT) is currently the standard of care for primary and secondary stroke prevention in children with sickle cell anemia (SCA). However, the effect of CBT on cerebrovascular p...
Arterial blood pressure in adult Nigerians with sickle cell anemia.
AIM AND OBJECTIVE: This study was aimed at comparing the arterial blood pressures in steady state adult sickle cell patients with those of age- and sex-matched healthy controls. METHODS: A descriptive...
Neonatal Screening of Sickle Cell Anemia: A Preliminary Report.
OBJECTIVE: To evaluate feasibility of systematic neonatal screening for sickle cell disease in Chhattisgarh. METHODS:...
