RPL554

Verona’s lead drug, RPL554, is a dual phosphodiesterase (PDE) 3 and 4 inhibitor being developed as a novel treatment for chronic obstructive airways disease as COPD (chronic obstructive pulmon...

Kadcyla (ado-trastuzumab emtansine)

Kadcyla™ (ado-trastuzumab emtansine or T-DM1) for the treatment of people with HER2-positive metastatic breast cancer (mBC) who have received prior treatment with Herceptin® (trastuzumab)...

Gastrointestinal Effects

Nutrition

Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In cri...

Immunocytokines

Although the human cytokines interleukin-2 (IL-2) and tumor necrosis factor (TNF) alpha are approved marketed for tumor therapy, their use is rather limited due to severe systemic side effects. Targ...

Artificial tears: How to select eyedrops for dry eyes

Artificial tears can relieve dry eyes — what to consider when choosing eyedrops for dry eyes.

Dry Eye

The surface of the eye is protected by tears. Tears are made up of 3 layers: a water layer, a (fatty or oily) layer, and a mucous layer. When there are not enough tears being produced by the eye, or i...

When rugby and mechanical science collide

The rugby maul can sometimes look like the most unscientific of game techniques, but players are now benefitting from a new technical training aid, designed with help from engineering experts at Herio...

Will ‘Side Effects’ Have Side Effects For Pharma?

There have been several movies over the years that have, in various ways, focused on the pharmaceutical industry and the latest to do so is ‘Side Effects,’ the Steve Soderbergh film that d...

Concussion treatment in rugby league may mislead public

Media representation of concussion management in rugby league could affect public understanding of appropriate medical care, according to a new study.

Statin Side Effects Are Usually Overcome

Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...

Statin Therapy Side Effects Go Away With Persistence

Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...

SNPing side effects: Sidebar: Inform Genomics Inc. Corporate Profile

SNPing side effects Inform Genomics Inc. Boston, Mass. Technology: SNP-based test to predict chemotherapy side effects Disease focus: Diagnostic Clinical status: NA Founded: 2010 by Ed Rubenstein, Sus...

Shoulder injuries in professional rugby: a retrospective analysis.

BACKGROUND: In the literature, little is known about the level and pattern of rugby injuries. Of the shoulder injuries reported, 51% of these are caused during a tackle, and 65% of all match injuries...

Tag rugby: a safe alternative? A review of hand injuries sustained playing tag rugby (2007 season).

Introduction Tag rugby is a non-contact, seven-a-side, team sport in which each player wears specially designed shorts with velcro 'tags' attached to them. While tag rugby is a relatively new sport it...

The effects of acute alcohol consumption on recovery from a simulated rugby match.

Abstract In this study, we investigated the effects of acute post-exercise alcohol consumption on measures of physical performance, creatine kinase, and immunoendocrine function in the 48 h followi...

The Ex Vivo Eye Irritation Test (EVEIT) in evaluation of artificial tears: Purite®-preserved versus unpreserved eye drops.

OBJECTIVE: Preservatives in artificial tears cause controversy. New developments such as the Purite® system have been introduced into the market, with the promise of little damage to the corneal surf...

Rugby Union on-field position and its relationship to shoulder injury leading to anterior reconstruction for instability.

Due to the unique demands of each position on the Rugby Union field, the likelihood of an athlete sustaining a dislocation of their shoulder joint that requires surgical reconstruction may be affected...