Search Results for "Side Effects Of Adiponectin"
Original Source: Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos.
BACKGROUND Adiponectin, a pleiotropic hormone secreted from adipose tissue, can mediate some negative effects of obesity on female health, and can participate in the impaired reproductive performance of obese women. Using a mouse model, we investigated expression of adiponectin receptors in ovulated oocytes and in vivo derived preimplantation embryos, and tested effects of different adiponectin isoforms on development of preimplantation embryos in vitro. METHODS AND RESULTS Using RT-PCR and immunohistochemi...
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Verona’s lead drug, RPL554, is a dual phosphodiesterase (PDE) 3 and 4 inhibitor being developed as a novel treatment for chronic obstructive airways disease as COPD (chronic obstructive pulmon...
Kadcyla (ado-trastuzumab emtansine)
Kadcyla™ (ado-trastuzumab emtansine or T-DM1) for the treatment of people with HER2-positive metastatic breast cancer (mBC) who have received prior treatment with Herceptin® (trastuzumab)...
Although the human cytokines interleukin-2 (IL-2) and tumor necrosis factor (TNF) alpha are approved marketed for tumor therapy, their use is rather limited due to severe systemic side effects. Targ...
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Urinary adiponectin as a marker for diabetic nephropathy
Urinary adiponectin may provide a novel biomarker for diabetic nephropathy, shows research from Finland.
Hair Growth–Promoting Effects of Adiponectin In Vitro
Will ‘Side Effects’ Have Side Effects For Pharma?
There have been several movies over the years that have, in various ways, focused on the pharmaceutical industry and the latest to do so is ‘Side Effects,’ the Steve Soderbergh film that d...
Low adiponectin in first trimester linked to GDM
(HealthDay)—Low adiponectin levels during the first trimester of pregnancy correlate with a higher level of insulin resistance and an increased risk of developing gestational diabetes mellitus (GDM)...
Statin Side Effects Are Usually Overcome
Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...
Statin Therapy Side Effects Go Away With Persistence
Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...
SNPing side effects: Sidebar: Inform Genomics Inc. Corporate Profile
SNPing side effects Inform Genomics Inc. Boston, Mass. Technology: SNP-based test to predict chemotherapy side effects Disease focus: Diagnostic Clinical status: NA Founded: 2010 by Ed Rubenstein, Sus...
Matching PubMed Articles
EFFECTS OF ADIPONECTIN ON HUMAN TROPHOBLAST INVASION.
Adiponectin is an adipokine with insulin-sensitizing, anti-inflammatory, anti-atherogenic, and anti-proliferative effects. The expression of specific adiponectin receptors in the placenta and in the e...
Adiponectin is produced from fatty tissue and has been reported to be involved with metabolic syndrome. Recently, adiponectin has been demonstrated to play a neuroprotective role against cerebral isch...
An APPL1-AMPK Signaling Axis Mediates Beneficial Metabolic Effects of Adiponectin in the Heart.
Adiponectin promotes cardioprotection by various mechanisms and this study used primary cardiomyocytes and the isolated working perfused heart to investigate cardiometabolic effects. We show in adult...
Adiponectin whose systemic levels are reduced in obesity-related diseases ameliorates insulin sensitivity and regulates biological processes like apoptosis, proliferation, migration and inflammation....
Adiponectin protects rat hippocampal neurons against excitotoxicity.
Adiponectin exerts multiple regulatory functions in the body and in the hypothalamus primarily through activation of its two receptors, adiponectin receptor1 and adiponectin receptor 2. Recent studies...
