Rho D Immune Globulin CSL

RSV Immune Globulin

CMV Immune Globulin CSL

Immune Response

Immune system

Integration of the movement of signaling microclusters with cellular motility in immunological synapses

TCR microcluster signaling occurs in cognate T cells after they encounter antigen-presenting cells. Krummel and colleagues show that immune synapses are motile as microclusters coalesce after the acti...

Glucocorticoid feedback uncovers retrograde opioid signaling at hypothalamic synapses

Wamsteeker Cusulin and colleagues report that stress-induced glucocorticoid release can trigger metaplasticity at GABAergic synapses on neuroendocrine neurons of the hypothalamus in rodents. Following...

Balancing connections for proper brain function

Neuropsychiatric conditions such as autism, schizophrenia and epilepsy involve an imbalance between two types of synapses in the brain: excitatory synapses that release the neurotransmitter glutamate,...

NSU to host conference on neuro immune conditions

Nova Southeastern University (NSU) will be hosting a conference on Saturday, Jan. 26 about the upcoming opening of the NSU College of Osteopathic Medicine's Institute for Neuro Immune Medicine.

Blocking Constant Interferon Signaling Allows the Immune System to Clear Chronic Viral Infections

Blocking constant Type I interferon signaling in mice diminished chronic immune activation and immune suppression and enabled the...

NSU-COM to hold grand opening for America's first Institute for Neuro Immune Medicine

Nova Southeastern University's College of Osteopathic Medicine (NSU-COM) will hold a grand opening for America's first Institute for Neuro Immune Medicine on Feb. 12.

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

Sensors of the NLR family generally activate innate immunity. Ting et al., however, demonstrate that the little-known NLRC3 negatively regulates Toll-like receptor signaling by altering ubiquitination...

Central synapses release a resource-efficient amount of glutamate

The authors use patch clamp recordings and computer simulations to determine the number of molecules of glutamate released at two central synapses. They find that the amount of glutamate released maxi...

Signaling at neuro/immune synapses.

Immunological and neural synapses share properties such as the synaptic cleft, adhesion molecules, stability, and polarity. However, the mismatch in scale has limited the utility of these comparisons....

Receptor signaling clusters in the immune synapse.

Signaling processes between various immune cells involve large-scale spatial reorganization of receptors and signaling molecules within the cell-cell junction. These structures, now collectively refer...

Central and Peripheral Cytokines Mediate Immune-Brain Connectivity.

The immune system is a homeostatic system that contributes to maintain the constancy of the molecular and cellular components of the organism. Immune cells can detect the intrusion of foreign antigens...

It takes nerves to fight infections: insights on neuro-immune interactions from C. elegans.

The innate immune response is evoked as a consequence of interactions between invading foreign infectious agents and host immune cells. A successful innate immune response is pivotal in maintaining th...

CYY-1/Cyclin Y and CDK-5 Differentially Regulate Synapse Elimination and Formation for Rewiring Neural Circuits.

The assembly and maturation of neural circuits require a delicate balance between synapse formation and elimination. The cellular and molecular mechanisms that coordinate synaptogenesis and synapse el...