Search Results for "Sjogren A Belimumab"

01:22 EST 26th January 2015 | BioPortfolio

Original Source: Efficacy and Safety of Belimumab in Subjects With Primary Sjögren's Syndrome

Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by an increase in BAFF (BLyS) levels and a resulting B cell hyperactivity. B cells are involved in the pathogenesis of SS in both systemic and glandular features, and B cell downregulation may lead to a decrease of disease activity. Moreover, pathogenesis of SS is closed to that of Systemic lupus erythematosus, where Belimumab has been proven to be effective.

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Aldeyra Therapeutics Submits IND Filing to FDA for Clinical Testing of NS2 in Patients With Sjogren-Larsson Syndrome

LEXINGTON, Mass., Jan. 5, 2015 (GLOBE NEWSWIRE) -- Aldeyra Therapeutics, Inc. (Nasdaq:ALDX) (Aldeyra), a biotechnology company focused on the development of products to treat diseases related to free...

Pacific Mercantile Bank Names Robert E. Sjogren Chief Operating Officer

COSTA MESA, Calif., Sept. 8, 2014 (GLOBE NEWSWIRE) -- Pacific Mercantile Bank ("the Bank"), the wholly owned subsidiary of Pacific Mercantile Bancorp (Nasdaq:PMBC), today announced that Robert E. Sjo...

Human medicines European public assessment report (EPAR): Benlysta, belimumab, Revision: 10, Authorised

Human medicines European public assessment report (EPAR): Benlysta, belimumab, Revision: 9, Authorised

Aldeyra Therapeutics Announces Collaboration With the National Organization for Rare Disorders to Enhance Awareness for Sjogren-Larsson Syndrome Patients

LEXINGTON, Mass., Dec. 4, 2014 (GLOBE NEWSWIRE) -- Aldeyra Therapeutics, Inc. (Nasdaq:ALDX) (Aldeyra), a biotechnology company focused on the development of products to treat diseases related to free...

Link between viral infection and autoimmune disease

Australian scientists have discovered that common viral infections can pave the way to autoimmune disease. Their work was published in the journal Immunity. The research focused on chronic cytomegalo...

NIHR Announces Pioneering Study to Test New Treatment for Sjogren’s Syndrome

The National Institute for Health Research (NIHR) has today announced the start of the UK’s first commercial trial of a new treatment for Sjogren’s syndrome. Up to half...

Sjogren's Syndrome Global Clinical Trials Review, H2, 2014

Recently added to the BioPortfolio report store, Sjogren's Syndrome Global Clinical Trials Review, H2, 2014 is a new report from GlobalData published on 2014-12-21. This 76-page report is available i...

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Update on belimumab for the management of systemic lupus erythematosus.

Introduction: Belimumab is a fully humanised mAb against B lymphocyte stimulator (B-LyS). It is the first biological drug to be licensed and approved by the US FDA and the European Medicines Evaluatio...

A23: favorable response to belimumab in childhood-onset systemic lupus erythematosus.

Belimumab (Benlysta) is a human monoclonal antibody inhibiting soluble B-lymphocyte stimulator that was approved by the Food and Drug Administration in 2011 for treatment of active, autoantibody-posit...

RESPIRATORY LESIONS DUE TO SJOGREN SYNDROME.

New treatments for inflammatory rheumatic disease.

As our understanding of the pathogenesis of autoimmune diseases is growing, new therapies are being developed to target disease-specific pathways. Since the introduction of etanercept in 1998, several...

Progressive hepatobiliary autoimmune diseases and cyclic citrullinated peptide antibodies.

Dear editor, Overlap syndrome is used to define the variant forms of autoimmune hepatitis (AIH) which presents with characteristics of AIH and two cholestatic syndromes, i.e. primary biliary cirrhosis...

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