Coma and Impaired Consciousness

Mechanical ventilation in ALI and ARDS

Acute Hypoxemic Respiratory Failure AHRF ARDS

Self-Management

Self-management is quite a new idea in healthcare, and it is for patient with long-term conditions to regain some control over their life, and to be able lead a better life,  despite their heal...

Vascular Dementia

Vascular Dementia accounts for 25% of all dementias (the second most commen cause after Alzheimers. It is the cumulative effects of many small strokes - patients often have evidence of vascular path...

EEG patterns indicate when patients lose, regain consciousness under propofol anesthesia

(Massachusetts General Hospital) Massachusetts General Hospital investigators have identified specific EEG signatures that indicate when patients lose and regain consciousness under the general anesth...

Definition of Acute Respiratory Distress Syndrome—Reply

In Reply: In response to Drs Namendys-Silva and Hernández-Garay, the exact adjustment to the PaO2/FIO2 ratio for altitude is unknown. We proposed the adjustment used in the ARDS Network clinical tria...

Definition of Acute Respiratory Distress Syndrome

To the Editor: The ARDS Definition Task Force presented a consensus draft definition developed by a panel of experts. They proposed 3 categories of ARDS based on degree of hypoxemia and, using a large...

Brain Has Distinct Activity Pattern When Losing Consciousness During Anesthesia

A new study from the US reveals for the first time, that the brain has a distinct pattern of electrical activity as patients lose consciousness during anesthesia. The pattern shows very slow oscilla...

Study suggests more accurate way to monitor patient awareness during general anesthesia

Massachusetts General Hospital investigators have identified specific EEG signatures that indicate when patients lose and regain consciousness under the general anesthetic drug propofol.

New definition for acute respiratory distress syndrome

Gordon D. Rubenfeld, M.D., of the Sunnybrook Health Sciences Center, Toronto, Canada, and colleagues with the ARDS (acute respiratory distress syndrome) Definition Task Force, developed a new definiti...

International panel updates definition of acute respiratory distress syndrome

Gordon D. Rubenfeld, M.D., of the Sunnybrook Health Sciences Center, Toronto, Canada, and colleagues with the ARDS (acute respiratory distress syndrome) Definition Task Force, developed a new definiti...

What is consciousness? A scientist’s perspective

We all know what consciousness is. We can tell when we’re awake, when we’re thinking, when we’re pondering the universe, but can anyone really explain the nature of this perception? Or even what...

ARDS - an update.

The acute respiratory distress syndrome (ARDS) is characterized by severe impairment of gas exchange and remains a challenge for modern intensive care medicine. The most common causes of ARDS are pneu...

Angiotensin-converting enzyme insertion/deletion polymorphism is associated with severe hypoxemia in pediatric ARDS.

PURPOSE: The D allele of the insertion/deletion (I/D) polymorphism of a 287-bp sequence in the angiotensin-converting enzyme (ACE) gene has been associated with an increased acti...

Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in ARDS.

ABSTRACT BACKGROUND: ARDS patients present with intrapulmonary and systemic coagulation abnormalities. We previously demonstrated that circulating KL-6/MUC1 could predict complications of disseminated...

The role of angiogenic factors and their soluble receptors in acute lung injury (ALI)/ acute respiratory distress syndrome (ARDS) associated with critical illness.

ABSTRACT: BACKGROUND: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by a disruption of the endothelium and alveolar epithelial barriers involving increased m...

Association of IL-10-1082 G/G genotype with lower mortality of acute respiratory distress syndrome in a Chinese population.

We aimed to investigate whether interleukin-10 (IL-10) -1082 G/G genotype is associated with lower mortality of acute respiratory distress syndrome (ARDS) in a Chinese population. A hospital-based cas...