Antiphospholipid syndrome nephropathy

Antiphospholipid Antibody Syndrome

Imaging studies

Electrophysiologic Studies EPS

Antibodies

Link Between Autoimmune Disease And Pregnancy Loss, Stroke

For years, researchers have known that antiphospholipid antibodies (aPLs) can cause pregnancy loss and clotting, but they haven't known the true scope of the problem. Now a new study provides the firs...

Rituximab shows promise for clinical problems tied to antiphospholipid antibodies

(Hospital for Special Surgery) Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies who suffer from aPL-related clinical problems that do not respon...

Statins have potential to treat an autoimmune clotting disorder called antiphospholipid syndrome

(Hospital for Special Surgery) New research suggests that statins, traditionally used for cholesterol lowering, could be used in the management of individuals who are at risk for developing clotting b...

Clinical Problems Tied To Antiphospholipid Antibodies May Be Improved By Rituximab

Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies (aPLs) who suffer from aPL-related clinical problems that do not respond to anticoagulation, su...

An Autoimmune Clotting Disorder Called Antiphospholipid Syndrome May Be Treatable With Statins

New research suggests that statins, traditionally used for cholesterol lowering, could be used in the management of individuals who are at risk for developing clotting because they have autoimmune ant...

Rituximab for the Antiphospholipid Antibody Syndrome

Dr. Kevin Deane comments on a pilot study of rituximab for the treatment of antiphospholipid syndrome. Medscape Rheumatology

Autoimmune disease linked to pregnancy loss, stroke more often than you'd expect

For years, researchers have known that antiphospholipid antibodies (aPLs) can cause pregnancy loss and clotting, but they haven't known the true scope of the problem. Now a new study provides the firs...

Autoimmune disease linked to pregnancy loss, stroke more often than you’d expect

For years, researchers have known that antiphospholipid antibodies (aPLs) can cause pregnancy loss and clotting, but they haven't known the true scope of the problem. Now a new study provides the firs...

Antiphospholipid antibody syndrome.

Antiphospholipid antibodies are directed against phospholipid-protein complexes and include lupus anticoagulant, anticardiolipin antibodies, and anti-beta-2 glycoprotein I antibodies. Antiphospholipid...

Autoantibodies Directed Against Domain I of Beta2-Glycoprotein I.

Patients diagnosed with the antiphospholipid syndrome typically suffer from vascular thrombosis, pregnancy morbidity, or a combination of the two. Due to the high prevalence of these clinical symptoms...

Association of antiphospholipid antibodies with valvulopathy in systemic lupus erythematosus: a systematic review.

Over the last few years, several studies in patients with systemic lupus erythematosus (SLE) have demonstrated an association between valvulopathy, including Libman-Sacks endocarditis (LS) and the pre...

Modified phosphatidylserine-dependent antithrombin ELISA enables identification of patients negative for other antiphospholipid antibodies and also detects low avidity antibodies.

Abstract Background: Two approaches for detecting anti-prothrombin antibodies have been described. The first detects antibodies against prothrombin alone and the second, phosphatidylserine-dependent a...

Is Testing for Antiphosphatidylethanolamine Antibodies Clinically Useful?

One of the most intriguing characteristics of the antiphospholipid syndrome (APS) is that diagnosis requires the combined presence of clinical abnormalities (thrombosis and/or miscarriages) and at lea...