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A novel surface marker helps scientists ‘fish out’ mammary gland stem cells

In a paper published in Proceedings of the National Academy of Sciences, scientists at Cold Spring Harbor Laboratory (CSHL) used a mouse model to identify a novel cell surface marker on mammary gland...

Novel surface marker helps scientists 'fish out' mammary gland stem cells

It is now possible to profile normal and cancerous mammary stem cells at an unprecedented high degree of purity. This may help identify genes that should be investigated as the next breast cancer drug...

Novel Method Enables Isolation of Nearly Pure Population of Mammary Gland Stem Cells

The surface protein marker CD1d is highly expressed on mammary gland stem cells, and the presence of this protein...

Bilateral internal mammary artery grafts safe in diabetic CABG patients

NEW YORK (Reuters Health) - A new study supports what some cardiothoracic surgeons have advocated for years: the use of both internal mammary arteries during coronary artery bypass grafting (CABG)...

A novel surface marker helps scientists 'fish out' mammary gland stem cells

(Cold Spring Harbor Laboratory) In an advancement by the Hannon lab at CSHL, it is now possible to profile normal and cancerous mammary stem cells at an unprecedented high degree of purity. This may h...

Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages

Notch signalling modulates fate decisions in stem and progenitor cells in various tissues. Artavanis-Tsakonas and colleagues use in vivo genetic labelling to uncover cell progenitors that are implicat...

His and hers: Male sex hormones control differences in mammary gland nerve growth

Scientists have found a surprising mechanism that gives male sex hormones like testosterone control over the gender-specific absence or presence of mammary gland nerves that sense the amount of milk a...

His and hers: Male hormones control differences in mammary gland nerve growth

Johns Hopkins scientists have found a surprising mechanism that gives male sex hormones like testosterone control over the gender-specific absence or presence of mammary gland nerves that sense the am...

The Normal Microenvironment Directs Mammary Gland Development.

Normal development of the mammary gland is a multidimensional process that is controlled in part by its mammary microenvironment. The mammary microenvironment is a defined location that encompasses ma...

Immune Cell Location and Function During Post-Natal Mammary Gland Development.

Post-natal mammary gland development requires complex interactions between the epithelial cells and various cell types within the stroma. Recent studies have illustrated the importance of immune cells...

Totally endoscopic quadruple coronary artery bypass grafting is feasible using robotic technology.

Multivessel robotic totally endoscopic coronary artery bypass grafting is currently under development. Quadruple totally endoscopic coronary artery bypass has so far not been reported. A 75-year-old p...

Functional Characterization of Stem Cell Activity in the Mouse Mammary Gland.

Any portion of the mouse mammary gland is capable of recapitulating a clonally derived complete and functional mammary tree upon transplantation into an epithelial divested mammary fat-pad of a recipi...

The mouse mammary microenvironment redirects mesoderm-derived bone marrow cells to a mammary epithelial progenitor cell fate.

Mammary stem cells reside in protected tissue locales (niches), where their reproductive potency remains essentially unchanged through life. Disruption of the tissue leads to a reduced capacity of dis...