Trimethoprim and Sulfamethoxazole

Obesity

Obesity is the condition in which excess fat has accumulated in the body (mostly in subcutaneous tissues). clinical obesity is considered to be present when a person has a BMI of over 30 (Oxford Dic...

Obesity and the Metabolic Syndrome

Nonalcoholic Steatohepatitis NASH

Nonalcoholic steatohepatitis or NASH is a common, often “silent” liver disease. It resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The major featu...

ATX-MS-1467 for patients with multiple sclerosis (MS)

ATX-MS-1467 is a novel treatment that was developed with the aim of working with the immune system to treat the underlying cause of disease rather than just treating the symptoms or suppressing the...

Call to adjust chemo dosing for obesity

Consistent guidance around dosing chemotherapy for obese patients is needed in the UK, members of the British Oncology Pharmacy Association...

Arrowhead Announces Dosing of First Patient with Anti-Obesity Treatment Adipotide in a Phase 1 ...

Zelboraf dosing rework

NIBR and UCSF researchers have shown that altering the dosing regimen of Zelboraf can prevent the development of drug resistance in mouse models of melanoma. The team will now test an intermittent Zel...

Peristaltic Pumps for the Pharmaceutical Industry

Vederflex have provided an award winning pharmaceutical dosing pump for MethaMeasure, helping to deliver a new kind of methadone dosing system. The pump will automate the dosing process, making rehab...

Precise dosing in microlitre range

Burkert presents micro dosing unit for liquids

Johnson Electric introduces miniature medication dosing system technology

Johnson Electric today announced a miniature medication dosing system technology under the Johnson Medtech brand. The subsystem platform provides a high precision dosing accuracy over device operatio...

From obesity genetics to the future of personalized obesity therapy

Genetic factors influence obesity risk with numerous variants and genes associated with differences in BMI and obesity. Here, Julia El-Sayed Moustafa and Philippe Froguel outline current knowledge in...

Genes behind obesity mapped in large-scale study

(Uppsala University) An international research team has identified seven new gene loci linked to obesity. Researchers were also able to show that the genetic mechanisms that cause extreme obesity are...

Genome Sequence of a Cold-Adaptable Sulfamethoxazole-Degrading Bacterium, Pseudomonas psychrophila HA-4.

Pseudomonas psychrophila HA-4 is a cold-adaptable, sulfamethoxazole-degrading bacterium. The genes related to its cold adaptation mechanism and sulfamethoxazole metabolism were unknown. We present the...

The effects of obesity on drug pharmacokinetics in humans.

Introduction : The prevalence of obesity and associated co-morbid conditions is increasing globally. Physiological changes accompanying obesity are likely to result in altered drug pharmacokinetics; h...

Therapeutic drug monitoring to adjust dosing in morbid obesity - a new use for an old methodology.

The phenomena of hunger and need at one end of the spectrum and obesity and plenty on the other is an anomaly of the 21(st) century, likely to be due to a combination of distributive inequities in fo...

Comparison of the pharmacokinetics of sulfamethoxazole in native Han and Tibetan male Chinese volunteers living at high altitude.

The aim of this study was to investigate the pharmacokinetics of sulfamethoxazole in native Han and Tibetan healthy Chinese subjects living chronically at high altitude. An open-labeled, controlled, p...

Osteomyelitis due to trimethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease.

Edwardsiella tarda, a catalase-positive bacillus widely distributed throughout nature, is generally susceptible to trimethoprim/sulfamethoxazole. We describe osteomyelitis due to trimethoprim/sulfamet...