Veregen

Veregen® is an ointment used to treat external genital warts. In the USA, Germany, Austria, Spain, Switzerland and Serbia, Veregen® is already marketed by our partners. Sales and marketing p...

Drug Delivery - news, views, blogs

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals.  Drug delivery technologies are patent protected formulat...

Crohns Disease

Crohns Disease is a chronic inflammatory disease, affecting the whole of the alimentary tract from mouth to anus, and all layers of the gut wall. The most commonly affected sites are the terminal il...

Generics Drugs - news, views, reports

A generic drug (generic drugs, short: generics) is a drug defined as "a drug product that is comparable to brand/reference listed drug product in dosage form, strength, route of administration,...

Varicella

Varicella zoster virus (VZV) is one of eight herpes viruses known to infect humans (and other vertebrates). Varicella-zoster virus is known by many names, including: chickenpox virus, varicella viru...

Sequential oral, topical tacrolimus benefits dermatitis

(HealthDay)—Sequential therapy with oral tacrolimus and topical tacrolimus may be an effective treatment for severe atopic dermatitis (AD), according to a pilot study published in the October issue...

Mothers taking tacrolimus can safely breastfeed

Breastfeeding does not increase blood levels of tacrolimus in infants born to women taking the drug, a new online study reveals (Clinical Journal of the American Society of Nephrology, 24 January 201...

Tacrolimus breast milk transfer concerns allayed

Breastfeeding mothers taking tacrolimus do not pass the immunosuppressant on to their babies when breastfeeding, study results show.

Clinical trial to study immunosuppressant tacrolimus against generics

A new study at the University of Cincinnati seeks to end the questions over generic-vs.-brand for a common immunosuppressive drug for transplant patients, tacrolimus.

Tacrolimus safe and effective for refractory ulcerative colitis

NEW YORK (Reuters Health) - Tacrolimus therapy can increase the likelihood of remission when ulcerative colitis (UC) won't respond to steroids, a new paper suggests.

Veloxis Pharmaceuticals to Present Data Differentiating LCP-Tacro™ from Available Tacrolimus Formulations at the Transformational Therapies and Diagnostics in Transplantation Conference

HORSHOLM, Denmark, Oct. 10, 2012 /PRNewswire/ -- Veloxis will give two upcoming data presentations that further define the profile of LCP-Tacro compared to other tacrolimus formulations.  The fir...

Tacrolimus shows short-term efficacy in refractory ulcerative colitis

NEW YORK (Reuters Health) - A retrospective German study has demonstrated that tacrolimus may be an effective option for corticosteroid refractory ulcerative colitis patients.

Astellas banks on existing data in surprise US re-filing of once-daily tacrolimus

After mulling on the quiet for several years whether to go ahead or not, Astellas has finally filed a US NDA for the once-daily capsule formulation of its immunosuppressant tacrolimus. The applicati...

Comparison of release and penetration of tacrolimus ointment reference and trial formulation after dermal application to pigs by liquid chromatography-electrospray ionization tandem mass spectrometry.

To investigate the consistency and bioequivalence of tacrolimus ointment reference and trial formulation, the tacrolimus concentrations in blood and skin were determined by HPLC-ESI-MS/MS following to...

Treatment of vitiligo with narrowband-UVB (TL01) combined with tacrolimus ointment (0.1%) vs. placebo ointment, a randomized right/left double-blind comparative study.

Background  Only a few, small double-blind clinical trials have been reported for the treatment of vitiligo. Narrowband-ultraviolet B (NB-UVB) is an established form of treatment for this condition....

Long-term efficacy and tolerability of tacrolimus 0.03% ointment in infants:* a two-year open-label study.

Background  Tacrolimus ointment is effective for treatment of moderate to severe atopic dermatitis (AD) in children aged ≥2 years (Br J Dermatol, 2004; 150: 554). Here, efficacy and tolerability...

Topical tacrolimus ointment for the treatment of lichen sclerosus, comparing genital and extragenital involvement.

Lichen sclerosus is a chronic inflammatory dermatosis presenting with significant sclerosis, atrophy and pruritus. The treatment for this condition remains unsatisfactory, with potent corticosteroids...

Dermal targeting of tacrolimus using colloidal carrier systems.

In the therapy of chronic inflammatory skin diseases, the epicutaneous application of anti-inflammatory drugs in combination with maintenance therapy leads to ideal therapeutic long term effects. In t...