Vitamin E Toxicity

Research has not found any adverse effects from consuming vitamin E in food. However, high doses of alpha-tocopherol supplements can cause hemorrhage and interrupt blood coagulation in animals, and...

Vascular Dementia

Vascular Dementia accounts for 25% of all dementias (the second most commen cause after Alzheimers. It is the cumulative effects of many small strokes - patients often have evidence of vascular path...

Spirometry Test

The gold standard in lung testing In the same way that blood pressure measurements provide a simple yet effective screening method for cardiovascular disease, spirometry tests can help to unmask t...

Gastroesophageal Reflux Disease GERD

GERD is a condition which develops when the reflux of stomach contents causes troublesome symptoms (ie at least two heartburns per week) and/or complications. Predisposing factors include dysfunctio...

Stroke Rehabilitation

A stroke, previously known medically as a cerebrovascular accident (CVA), is the rapidly developing loss of brain function(s) due to disturbance in the blood supply to the brain. This can be due to...

FDA approves Nucynta ER for diabetic peripheral neuropathy

Sales of the non-extended release version of Nucynta were $140 million in 2011 and are expected to reach $600 million in 2016, according to the average forecast of analysts polled by Thomson Reute...

FDA approves wider use for J&J Nucynta ER pain drug

WASHINGTON (Reuters) - Johnson & Johnson unit Janssen Pharmaceuticals said on Wednesday it received U.S. regulatory approval for a wider use of its painkiller Nucynta ER, for nerve damage brought on b...

Janssen pays $10m upfront to license technology for Nucynta ER from Depomed

Depomed will earn $10 million upfront and low single-digit royalties through the end of 2021 on sales of Nucynta ER (tapentadol extended-release tablets) in the US, Canada and Japan under an agreement...

Janssen's Nucynta celebrates 1st birthday by adding new DPN indication

Johnson & Johnson unit Janssen Pharmaceuticals celebrated the one-year birthday of its chronic pain drug Nucynta ER (tapentadol) by gaining another US indication. This time, the US FDA has approve...

FDA Approves NUCYNTA ER (tapentadol) Extended-Release Oral Tablets

Janssen Pharmaceuticals, Inc. has announced the FDA has approved the supplemental New Drug Application (sNDA) for NUCYNTA ER (tapentadol) extended-release tablets, an oral analgesic taken twice daily,...

FDA Approves Nucynta ER (tapentadol) Extended-Release Oral Tablets for the Management of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

RARITAN, N.J., Aug. 29, 2012 /PRNewswire/ -- Janssen Pharmaceuticals, Inc. today announced the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for Nuc...

FDA OKs new indication for Janssen's Nucynta and fast tracks Zytiga sNDA

There were two pieces of good news for US health care giant Johnson & Johnson (NYSE: JNJ) subsidiaries yesterday. First, the US Food and Drug Administration has approved Janssen Pharmaceuticals' suppl...

[Janssen] gets rights to use [Depomed]'s {Acuform} IP to deliver {Nucynta} ER

[Johnson & Johnson]’s [Janssen Pharmaceuticals Inc.] has licensed non-exclusive rights to [Depomed Inc.]’s {Acuform} gastric retentive drug delivery technology. Janssen has also gained other right...

Taking sides over taking call: New limits for first-year medical residents meet resistance from pathologists.

The influence of prior knowledge on the retrieval-directed function of note taking in prior knowledge activation.

Background Prior knowledge activation facilitates learning. Note taking during prior knowledge activation (i.e., note taking directed at retrieving information from memory) might facilitate the activa...

Individual differences in speakers' perspective taking: The roles of executive control and working memory.

Both speaking and listening require taking into account the perspective of one's communicative partner. Is perspective taking a domain-specific process internal to the language production and comprehe...

Perspective taking associated with social relationships: a NIRS study.

Social neuroscience has made considerable progress in revealing the mechanisms underlying empathy. We focused on the mechanism of perspective taking, which is one aspect of the empathic process that i...

Systematic review of tapentadol in chronic severe pain.

Abstract Aim: A systematic review of chronic pain treatment with strong opioids (step 3 WHO pain ladder) and a comparison to a new drug recently approved for the treatment of severe chronic pain in Eu...