Search Results for "Tamoxifen Amount Of Bone Adding"
Original Source: Tamoxifen to Prevent Bone Loss and Heart Disease in Premenopausal Women Receiving Chemotherapy for Stage I or Stage II Breast Cancer
RATIONALE: Tamoxifen may be able to increase bone density and decrease cholesterol in women who are undergoing chemotherapy for breast cancer. PURPOSE: Clinical trial to study the effectiveness of tamoxifen in preventing bone loss and heart disease caused by chemotherapy treatment in premenopausal women who have stage I or stage II breast cancer.
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Selective Estrogen Receptor Modulators SERMs
Selective estrogen receptor modulators (SERMs) act as estrogen receptor (ER) agonists or antagonist depending on the targeted tissue and the specific configuration of the used SERM. Effects on bone, e...
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10 Years of Tamoxifen Better Than Five: Are You Kidding Me?
FIRST PERSON | Results from a recent study called ATLAS (adjuvant tamoxifen longer against shorter) show that 10 years of tamoxifen therapy is better than the current treatment of five years. The find...
Tamoxifen And Coffee Consumption May Help Prevent Return Of Breast Cancer
Drinking coffee could decrease the risk of breast cancer recurring in patients taking the widely used drug Tamoxifen, a study at Lund University in Sweden has found. Patients who took the pill, along...
Draft NICE guideline recommends tamoxifen as chemoprevention
Tamoxifen should be offered to women who have not had breast cancer but are at high risk of developing the disease...
Predicting Tamoxifen Resistance In Breast Cancer Treatment
Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen. Tamoxifen - used alongside traditional chemotherapy...
Tamoxifen helps muscular dystrophy symptoms in mice
A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse [...]
Researchers at Karolinska Institutet have developed a method for assessing the effect of tamoxifen, a common drug to prevent the relapse of breast cancer. The key lies in monitoring changes in the pro...
Biomarker Of Tamoxifen Resistance In Breast Cancer Identified
New research led by the University of Manchester in the UK has found a biomarker or molecular "flag" in women with breast cancer who do not repond, or who have become resistant, to treatment with the...
[Comment] Extended adjuvant tamoxifen for breast cancer—a new era?
Tamoxifen has been shown to reduce the risk of relapse and mortality in randomised trials of women with operable oestrogen receptor (ER)-positive breast cancer, with treatment for 5 years showing grea...
Matching PubMed Articles
Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells.
ABSTRACT: BACKGROUND: Claudin-1 is a membrane protein of tight junctions, and is associated with the development of various cancers. However, the significance of claudin-1 expression in cancer cells i...
Background: Use of aromatase inhibitors in women with postmenopausal breast cancer accompanies risks of bone loss. We evaluated changes in bone mineral density (BMD) and bone turnover markers in patie...
The objective of this study was to evaluate the impact of tamoxifen treatment on amount of fibroglandular tissue (FGT), background parenchymal enhancement (BPE), and cysts on breast MRI. Retrospec...
Chromosomal aberration in the post-implantation embryos sired by tamoxifen treated male rats.
Tamoxifen is a synthetic non-steroidal Selective Estrogen Receptor Modulator used in the treatment of breast cancer and in treatment of male fertility. Earlier studies from our laboratory had demonstr...
Preparation and evaluation of carborane analogues of tamoxifen.
A stereoselective synthesis of closo carborane analogues of tamoxifen was developed where the products represent a new approach to developing metabolically robust SERMs. The A-ring found in the backbo...
