Tankyrases Pages on BioPortfolio:

BioPortfolio - Tankyrases
Tankyrases - BioPortfolio - Indepth. ... Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and ...
http://www.bioportfolio.com/indepth/Tankyrases.html...

The C. elegans gene pme-5: molecular cloning and role in the DNA ...
Tankyrases are recently identified proteins characterized by ankyrin repeats and ... In vertebrates, tankyrases mediate protein-protein interactions via the ...
http://www.bioportfolio.com/bookshop/search/Tankyrases/...

Biotechnology, Pharmaceutical and Life Science Email addresses for ...
BioPortfolio the comprehensive email list supplier for data, information, search engine and services on biotechnology, pharmaceutical and healthcare ...
http://www.bioportfolio.com/advertis/bioemail.htm...

BioPortfolio - Belozersky A. N.
BioPortfolio - Tankyrases research 28th May, 2008, Belozersky Institute of ... http://www.bioportfolio.com/indepth/Tankyrases/research.html. ...
http://www.bioportfolio.com/search/Belozersky_A._N..html...

BioPortfolio - PARP4
Six genes encoding "bona fide" PARP enzymes have been identified in mammalians: PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrases-1 and PARP6/Tankyrases-2. ...
http://www.bioportfolio.com/search/PARP4.html...

BioPortfolio - sterile alpha motif
Yeast two-hybrid and cross-linking experiments show that both tankyrases can multimerize through their sterile-alpha motif domains. ...
http://www.bioportfolio.com/search/sterile_alpha_motif.html...

Results from other life science and pharmaceutical sites:

The telomeric PARP, tankyrases, as targets for cancer therapy
Tankyrases are poly(ADP-ribose) polymerases that enhance telomerase access to telomeres. Tankyrase 1 modulates telomerase inhibition in human cancer cells ...
http://www.nature.com/bjc/journal/v94/n3/full/6602951a.html...

Human tankyrases are aberrantly expressed in colon...[Cancer ...
Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients
...
http://www.ncbi.nlm.nih.gov/pubmed/18026951...

The telomeric PARP, tankyrases, as targets for cancer therapy
British Journal of Cancer (BJC) provides a forum for communicating the very best cancer research to a broad audience. BJC works with a distinguished team of ...
https://secure.nature.com/bjc/journal/v94/n3/full/6602951a.h...

Generation and Characterization of Telomere Length Maintenance in ...
This finding suggests that either mouse tankyrases 1 and 2 have redundant functions in telomere length maintenance or that mouse tankyrase 2 differs from
...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=14...

The C. elegans gene pme-5: molecular cloning and r...[DNA Repair ...
Tankyrases are recently identified proteins characterized by ankyrin repeats and ... In vertebrates, tankyrases mediate protein-protein interactions via the ...
http://www.ncbi.nlm.nih.gov/pubmed/14706351...

Vertebrate tankyrase domain structure and sterile alpha motif (SAM ...
Tankyrases 1 and 2 are two highly related poly(ADP-ribose) polymerases that ... Yeast two-hybrid and cross-linking experiments show that both tankyrases can ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=12...

Tankyrase polymerization is controlled by its ster...[Mol Cell ...
Thus, tankyrases appear to be master scaffolding proteins that regulate the formation ... This implies a common scaffolding function for tankyrases at each
...
http://www.ncbi.nlm.nih.gov/pubmed/15509784...

Tankyrase 1 and Tankyrase 2 Are Essential but Redundant for Mouse ...
Human tankyrases post-translationally modify multiple proteins involved in ... To date, however, little is known about in vivo functions for tankyrases. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=24...

TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length ...
The tankyrases have been implicated in controlling telomere length and in numerous other cellular processes15, 16. Nuclear overexpression of tankyrases
...
http://www.nature.com/ng/journal/v36/n6/full/ng1360.html...

Insulin-stimulated exocytosis of GLUT4 is enhanced by IRAP and its ...
Both tankyrases exhibit an unusual catalytic activity known as PARP (poly-ADP- ribose polymerase) activity [20,21], which can modify tankyrases themselves as
...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=17...

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