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Search Results for "The Chain Of Infection Of Malaria"

18:56 EDT 29th July 2014 | BioPortfolio

Original Source: Malaria Infection Diagnosed by Polymerase Chain Reaction (PCR) as a Means of Evaluating Pre-Erythrocytic Candidate Malaria Vaccines

The ability to test candidate pre-erythrocytic stage malaria vaccines, using a well-established sporozoite challenge model, in a field setting with group sizes of tens rather than hundreds of volunteers would greatly facilitate identification of the most promising vaccine candidates. The investigators assessed the suitability and acceptability of this method in a field trial in semi-immune volunteers exposed to natural infection during the high malaria transmission season.

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Falciparum malaria

IgA Heavy Chain Chain Disease

IgG Heavy Chain Chain Disease

IgM Heavy Chain Chain Disease

Malaria Vaccines

Malaria represents one of the international community’s most pressing public health problems. The disease exacts an economic toll of roughly $12 billion a year in Africa. A vaccine is an ess...

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Despite unprecedented investment in malaria control, most Africans at high risk of contracting deadly malaria

Despite unprecedented investment in malaria control in Africa over the past decade, about 57% of the population still live in areas where risk of infection remains moderate to high, according to new r...

Research finding could lead to new strategies for malaria control

Researchers have found the first evidence of an intercellular bacterial infection in natural populations of two species of Anopheles mosquitoes, the major vectors of malaria in Africa. The infection,...

Infection in malaria-transmitting mosquito discovered

(Harvard School of Public Health) Researchers have found the first evidence of an intercellular bacterial infection in natural populations of two species of Anopheles mosquitoes, the major vectors of...

Scientists identify potential vaccine candidate for pediatric malaria

Researchers have identified a substance, or antigen, that generates antibodies that can hinder the ability of malaria parasites to multiply, which may protect against severe malaria infection.

How the immune system protects children from malaria

Children who live in regions of the world where malaria is common can mount an immune response to infection with malaria parasites that may enable them to avoid repeated bouts of high fever and illnes...

First controlled malaria infection trial in Africa paves way for drug and vaccine development

(Burness Communications) An international research team today reports the first-ever clinical trial demonstrating controlled malaria infection in an African nation in the modern era. The study, publis...

Detecting Parasite Clearance and Recurrent Malaria Infection

This study tests the efficacy of two rapid diagnostic tests in their ability to detect parasite clearance and recurrent infection in parasite-based malaria patients after treatment. Malaria Journal

Findings may help researchers develop future interventions to prevent malaria

According to a study published today in PLOS Pathogens, children who live in regions of the world where malaria is common can mount an immune response to infection with malaria parasites that may enab...

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Infection and Co-infection with Helminths and Plasmodium among School Children in Côte d'Ivoire: Results from a National Cross-Sectional Survey.

Helminth infection and malaria remain major causes of ill-health in the tropics and subtropics. There are several shared risk factors (e.g., poverty), and hence, helminth infection and malaria overlap...

Increased Severity and Mortality in Adults Co-Infected with Malaria and HIV in Maputo, Mozambique: A Prospective Cross-Sectional Study.

Co-infection with falciparum malaria and HIV-1 increases the severity and mortality of both infections in unstable malaria-transmission areas. In contrast, in stable transmission areas, HIV co-infecti...

Barriers to Malaria Control among Marginalized Tribal Communities: A Qualitative Study.

Malaria infection accounts for over one million deaths worldwide annually. India has the highest number of malaria deaths outside Africa, with half among Indian tribal communities. Our study sought to...

NOS2 variants reveal a dual genetic control of nitric oxide levels, susceptibility to Plasmodium infection and cerebral malaria.

Nitric oxide (NO) is a proposed component of malaria pathogenesis and the inducible nitric oxide synthase gene (NOS2) has been associated to malaria susceptibility. We analyzed the role of NOS2 polymo...

Incidence of malaria-related fever and morbidity due to Plasmodium falciparum among HIV1-infected pregnant women: a prospective cohort study in South Benin.

Malaria and HIV are two major causes of morbidity and mortality among pregnant women in sub-Saharan Africa. Foetal and neonatal outcomes of this co-infection have been extensively studied. However, li...

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