Search Results for "The Chain Of Infection Of Malaria"

13:06 EST 28th November 2014 | BioPortfolio

Original Source: Malaria Infection Diagnosed by Polymerase Chain Reaction (PCR) as a Means of Evaluating Pre-Erythrocytic Candidate Malaria Vaccines

The ability to test candidate pre-erythrocytic stage malaria vaccines, using a well-established sporozoite challenge model, in a field setting with group sizes of tens rather than hundreds of volunteers would greatly facilitate identification of the most promising vaccine candidates. The investigators assessed the suitability and acceptability of this method in a field trial in semi-immune volunteers exposed to natural infection during the high malaria transmission season.

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Falciparum malaria

IgA Heavy Chain Chain Disease

IgG Heavy Chain Chain Disease

IgM Heavy Chain Chain Disease

Malaria Vaccines

Malaria represents one of the international community’s most pressing public health problems. The disease exacts an economic toll of roughly $12 billion a year in Africa. A vaccine is an ess...

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Infection in malaria-transmitting mosquito discovered

(Harvard School of Public Health) Researchers have found the first evidence of an intercellular bacterial infection in natural populations of two species of Anopheles mosquitoes, the major vectors of ...

First controlled malaria infection trial in Africa paves way for drug and vaccine development

(Burness Communications) An international research team today reports the first-ever clinical trial demonstrating controlled malaria infection in an African nation in the modern era. The study, publis...

Increased Dosing of Malaria Drug in Children May Lower Infection Risk

Piperaquine is a long-acting malaria drug that kills residual parasites and decreases the risk of reinfection.Read more about Increased Dosing of Malaria Drug in Children May Lower Infection Risk

Innate sensing of malaria parasites

Malaria infections can result in deleterious activation of innate immune cells. In this Review, the authors summarize how the Plasmodium parasite is recognized by innate immune receptors, and discuss ...

New malaria vaccines to prevent infection and block transmission get a shot in the arm

(Burness Communications) In support of a bold quest to rid the world entirely of malaria, the Bill & Melinda Gates Foundation today announced an award of US$156 million to PATH to support the PATH Mal...

Why humans don't suffer from chimpanzee malaria

(Wellcome Trust Sanger Institute) The DNA region controlling red-blood-cell invasion holds the genetic key to human malaria infection, according to new research.By comparing the genomes of malaria par...

Severe Plasmodium falciparum Infection Mimicking Acute MI

Don't forget the travel history. This presumed myocardial infarction was actually a severe case of malaria. Malaria Journal

Increased dosing of malaria drug in children could decrease risk of infection

Piperaquine is a long-acting malaria drug that kills residual parasites and decreases the risk of reinfection. A study led by Uppsala University researcher Martin Bergstrand shows that increasing the ...

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Infection and Co-infection with Helminths and Plasmodium among School Children in Côte d'Ivoire: Results from a National Cross-Sectional Survey.

Helminth infection and malaria remain major causes of ill-health in the tropics and subtropics. There are several shared risk factors (e.g., poverty), and hence, helminth infection and malaria overlap...

Increased Severity and Mortality in Adults Co-Infected with Malaria and HIV in Maputo, Mozambique: A Prospective Cross-Sectional Study.

Co-infection with falciparum malaria and HIV-1 increases the severity and mortality of both infections in unstable malaria-transmission areas. In contrast, in stable transmission areas, HIV co-infecti...

P. vivax Malaria and Dengue Fever Co-infection: A Cross-Sectional Study in the Brazilian Amazon.

Malaria and dengue are the most prevalent vector-borne diseases worldwide and represent major public health problems. Both are endemic in tropical regions, propitiating co-infection. Only few co-infec...

Safety and Comparability of Controlled Human Plasmodium falciparum Infection by Mosquito Bite in Malaria-Naïve Subjects at a New Facility for Sporozoite Challenge.

Controlled human malaria infection (CHMI) studies which recapitulate mosquito-borne infection are a critical tool to identify protective vaccine and drug candidates for advancement to field trials. In...

Incidence of malaria-related fever and morbidity due to Plasmodium falciparum among HIV1-infected pregnant women: a prospective cohort study in South Benin.

Malaria and HIV are two major causes of morbidity and mortality among pregnant women in sub-Saharan Africa. Foetal and neonatal outcomes of this co-infection have been extensively studied. However, li...

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