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Search Results for "The Chain Of Infection Of Malaria"

17:37 EDT 17th April 2014 | BioPortfolio

Original Source: Malaria Infection Diagnosed by Polymerase Chain Reaction (PCR) as a Means of Evaluating Pre-Erythrocytic Candidate Malaria Vaccines

The ability to test candidate pre-erythrocytic stage malaria vaccines, using a well-established sporozoite challenge model, in a field setting with group sizes of tens rather than hundreds of volunteers would greatly facilitate identification of the most promising vaccine candidates. The investigators assessed the suitability and acceptability of this method in a field trial in semi-immune volunteers exposed to natural infection during the high malaria transmission season.

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Falciparum malaria

IgM Heavy Chain Chain Disease

IgA Heavy Chain Chain Disease

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Malaria Vaccines

Malaria represents one of the international community’s most pressing public health problems. The disease exacts an economic toll of roughly $12 billion a year in Africa. A vaccine is an ess...

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Despite unprecedented investment in malaria control, most Africans at high risk of contracting deadly malaria

Despite unprecedented investment in malaria control in Africa over the past decade, about 57% of the population still live in areas where risk of infection remains moderate to high, according to new r...

Detecting Parasite Clearance and Recurrent Malaria Infection

This study tests the efficacy of two rapid diagnostic tests in their ability to detect parasite clearance and recurrent infection in parasite-based malaria patients after treatment. Malaria Journal

Malaria: 57% of African population live in high-risk infection areas

In 2010, 90% of all malaria deaths occurred in populations living in the African region of the World Health Organization. Although the past 10 years have seen major investments in malaria control in A...

Prevention and Management of Malaria During Pregnancy

Are women in Africa using available prevention strategies to prevent malaria infection in pregnancy? Malaria Journal

Drug protects mice against malaria brain damage, raises levels of BDNF in humans

Cerebral malaria is a serious complication of infection with the malaria parasite, affecting approximately one in a thousand children in areas where malaria is common. Many of the patients die, and am...

Drug protects mice against malaria brain damage and raises levels of a neuroprotective factor in humans

Cerebral malaria is a serious complication of infection with the malaria parasite, affecting approximately one in a thousand children in areas where malaria is common. Many of the patients die, and am...

[Comment] Malaria control in Africa: progress but still much to do

During the past two decades, the international community has invested heavily in malaria control, especially in sub-Saharan Africa, with support increasing from around US$100 million in 2000 to nearly...

The malaria pathogen's cellular skeleton under a super-microscope

(Helmholtz Centre for Infection Research) The tropical disease malaria is caused by the Plasmodium parasite. For its survival and propagation, Plasmodium requires a protein called actin. Scientists of...

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Increased Severity and Mortality in Adults Co-Infected with Malaria and HIV in Maputo, Mozambique: A Prospective Cross-Sectional Study.

Co-infection with falciparum malaria and HIV-1 increases the severity and mortality of both infections in unstable malaria-transmission areas. In contrast, in stable transmission areas, HIV co-infecti...

Barriers to Malaria Control among Marginalized Tribal Communities: A Qualitative Study.

Malaria infection accounts for over one million deaths worldwide annually. India has the highest number of malaria deaths outside Africa, with half among Indian tribal communities. Our study sought to...

NOS2 variants reveal a dual genetic control of nitric oxide levels, susceptibility to Plasmodium infection and cerebral malaria.

Nitric oxide (NO) is a proposed component of malaria pathogenesis and the inducible nitric oxide synthase gene (NOS2) has been associated to malaria susceptibility. We analyzed the role of NOS2 polymo...

Immunological disturbances associated with malarial infection.

Malaria is a reemerging disease in the countries where it was eradicated previously, whereas it is endemic in many countries including tropical countries. In India, malarial infection is on rise due t...

Malaria, primigravidae, and antibodies: knowledge gained and future perspectives.

Pregnant women have an increased risk of malaria infection, independent of previously acquired immunity. Women in their first pregnancy and children under the age of five are the primary victims of ma...

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