Management of Adverse Effects

Adverse drug effects

Adverse Drug Reactions

Vitamin E Toxicity

Research has not found any adverse effects from consuming vitamin E in food. However, high doses of alpha-tocopherol supplements can cause hemorrhage and interrupt blood coagulation in animals, and...

Gastrointestinal Effects

Rituximab cuts relapse of 'ANCA' vasculitis

NEW YORK (Reuters Health) - Rituximab helps maintain remission in patients with relapsing vasculitis associated with autoantibodies against neutrophil cytoplasmic antigens (ANCA), UK researchers r...

Rituximab Works in ANCA-Linked Vasculitis (CME/CE)

WASHINGTON (MedPage Today) -- Rituximab given as adjunctive therapy to children with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis dramatically lowered the dosage of cyclophosphamid...

Complications of long-term therapy for ANCA-associated systemic vasculitis

Antineutrophil cytoplasmic antibody-associated systemic vasculitides (AASVs) are a group of inflammatory disorders that largely affect the pulmonary and renal vascular beds. Although the advent of eff...

ANCA-associated vasculitis has genetic component

(HealthDay) -- A genome-wide association study of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis shows a genetic contribution to disease susceptibility, which differs between granulo...

Vasculitis: Refining phenotypes in ANCA-associated vasculitis

As granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) share histopathologic and clinical features, including the presence of antineutrophil cytoplasmic autoantibodies (ANCAs), p...

[Review] Adverse effects of antiepileptic drugs

More than 150 years after bromide was introduced as the first antiepileptic drug, adverse effects remain a leading cause of treatment failure and a major determinant of impaired health-related quality...

New radiation treatment techniques can reduce risk of neurocognitive adverse effects in children

Children who undergo brain radiation therapy run a significant risk of suffering from permanent neurocognitive adverse effects. These adverse effects are due to the fact that the radiation often encou...

New radiation therapy can reduce risk of neurocognitive adverse effects in children

Children who undergo brain radiation therapy run a significant risk of suffering from permanent neurocognitive adverse effects. These adverse effects are due to the fact that the radiation often encou...

Acute-on-chronic liver failure due to thiamazole in a patient with hyperthyroidism and trilogy of Fallot: case report.

ABSTRACT: BACKGROUND: Thiamazole is a widely used antithyroid agent that has been approved for the treatment of hyperthyroidism. Although thiamazole-induced hepatotoxicity is a main side effect, it ma...

Determination of thiamazole in pharmaceutical samples by phosphorus molybdenum blue spectrophotometry.

A novel method is established to determine thiamazole by phosphorus molybdenum blue spectrophotometry. The experiment indicates that PO(4)(3-) reacts with Mo(7)O(24)(6-) in 0.30mol/L H(2)SO(4) solutio...

Influence of myeloperoxidase by anti-myeloperoxidase antibodies and its association with the disease activity in microscopic polyangiitis.

Objectives. ANCAs with specificity for MPO are serological markers of ANCA-associated vasculitides, especially microscopic polyangiitis (MPA). This study investigated potential associations between th...

Successful Treatment with Rituximab in a Patient with TTP Secondary to Severe ANCA-Associated Vasculitis.

We report a case of thrombotic thrombocytopenic purpura (TTP) secondary to antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis treated by rituximab. TTP secondary to ANCA-associated vascu...

Two subtypes of Churg-Strauss syndrome with neuropathy: the roles of eosinophils and ANCA.

The aim of this study was to clarify the differences in the pathogenesis of neuropathy between myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA)-positive and -negative patients with Churg...