Thrombin Omrix

Fibrin sealant OMRIX

Thrombin W-L

Thrombin-Collagen Gel

Thrombin-Collagen

Self‐assembled DNA‐based giant thrombin nanoparticles for controlled release

Protein‐aptamer interactions have been used in a wide range of fields including medical diagnosis and protein delivery. Herein, we report a method for thrombin delivery with thrombin binding aptamer...

Thrombin sponge speeds cervical spine surgery discharge

Application of a thrombin-soaked sponge after posterior cervical spine surgery allows patients to leave hospital earlier than normally expected, suggests research.

The Medicines Company in over $105 million deal with Bristol-Myers for Recothrom; buys Incline Thera

Pharma major Bristol-Myers Squibb (NYSE: BMY) and fellow-USA-based The Medicines Company (Nasdaq: MDCO) have signed a global license and two year collaboration for Recothrom (thrombin alfa), a recombi...

Potential For New Generation Of Anticoagulants And Improving The Fight Against The Spread Of Malaria

An international project lead by the Molecular and Cell Biology Institute of Porto University with the participation of researchers from IMIM (Hospital del Mar Medical Research Institute) has, for the...

Architect 2nd Generation Testosterone Assay regulatory update

ClonoSEQ Assay Detects Minimal Residual Disease in Blood-based Cancers

Adaptive Biotechnologies, a leading provider of next-generation sequencing assays for the adaptive immune system, has introduced clonoSEQ, a clinical assay to measure minimal residual disease (MRD) in...

[Comment] Improving long-term outcome after myocardial infarction

Despite several large clinical trials, the best treatment strategy for long-term secondary prevention of thrombosis after myocardial infarction is unclear. Increasing anti-thrombotic treatment, especi...

2nd-gen testosterone assay from Abbott gets FDA OK

Abbott has been cleared by the FDA to market its Architect 2nd Generation Testosterone Assay, which is used to measure testos -More- AssurX helps medical device companies meet tough FDA/regu...

A thrombin generation assay may reduce the need for compression ultrasonography for the exclusion of deep venous thrombosis in the elderly.

Abstract Introduction. The exclusion of deep venous thrombosis (DVT) by pre-test probability (PTP) and D-dimer in the elderly is safe, but has a low specificity. There is increasing interest in the di...

Monitoring platelet dependent thrombin generation in mice.

Calibrated automated thrombin generation assay was adapted to measure thrombin generation in platelet rich plasma from mice. Vena cava phlebotomy appeared the best technique for blood sampling. The co...

The Influence of Tissue Factor and Tissue Factor Pathway Inhibitor Polymorphisms on Thrombin Generation in Stable Coronary Artery Disease.

In patients with stable coronary heart disease (n = 1,001) we investigated the influence of tissue factor (TF) and TF pathway inhibitor (TFPI) polymorphisms on thrombin generation in vivo, measured by...

Thrombin generation in Cushing's Syndrome: do the conventional clotting indices tell the whole truth?

Cushing's Syndrome (CS) is associated with an increased mortality, where hypercoagulability seems to have a crucial role in both arterial and venous thrombosis. Parameters of in vitro thrombin generat...

Validation of the calibrated thrombin generation test (cTGT) as the reference assay to evaluate the procoagulant activity of nanomaterials.

Abstract We validated a preclinical toxicological screening assay and provided guidelines to evaluate the potential impact of nanoparticles (NPs) on blood coagulation. Five NPs with various physicoche...