Metabotropic Glutamate Receptor 4 (mGluR4)

Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of the metabotropic glutamate receptor famil...

Parathyroid Hormone PTH Receptor

There are two known parathyroid hormone receptors in mammals termed PTH1R and PTH2R. These receptors bind parathyroid hormone and are members of the GPCR family of transmembrane proteins. * parathy...

Interleukin 6 IL 6 Receptor IL 6R

Although the causes of rheumatoid arthritis are not fully understood, constitutive overproduction of interleukin-6 (IL-6), a multifunctional cytokine that regulates immune response, inflammatory react...

HER2 receptor Mab rDNA

Interleukin IL-6 receptor Mab rDNA

Remote Ischaemic Preconditioning in Coronary Artery Bypass Surgery

Remote ischaemic preconditioning consists of protection of an organ from a sustained ischaemic event. Does it improve patient outcomes in CABG? Heart

Ischemic Preconditioning for Contrast-Induced AKI

This F1000 commentary reports on a study whose findings support the use of ischemic preconditioning in preventing contrast-induced acute kidney injury in high-risk patients. Faculty of 1000

[Review] Cardioprotection: chances and challenges of its translation to the clinic

Myocardial infarct size is a major determinant of prognosis. Ischaemic preconditioning with brief coronary occlusion and reperfusion before a sustained period of coronary occlusion with reperfusion de...

The protective roles of autophagy in ischemic preconditioning

Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21

Acute kidney injury: Ischaemic preconditioning for preventing contrast-induced AKI

Mitochondrial ROS production and subsequent ERK phosphorylation are necessary for temperature preconditioning of isolated ventricular myocytes

SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in rat brain

Isoflurane preconditioning and postconditioning in rat hippocampal neurons.

The volatile anesthetic isoflurane is capable of inducing preconditioning and postconditioning effects in the brain. However, the mechanisms for these neuroprotective effects are not fully understood....

Cardioprotection from remote preconditioning involves spinal opioid receptor activation.

Remote preconditioning is a powerful and potentially clinically viable mode of cardioprotection. The mechanisms underlying its transmission process have not been extensively studied. The aim of this s...

Hyperoxia preconditioning: the next frontier in neurology?

Oxygen is indispensable for all aerobic organisms and has become one of the most widely used therapeutic agents. Currently, oxygen not only is applied in the treatment of diseases, but becomes a modal...

Isoflurane preconditioning protects neurons from male and female mice against oxygen and glucose deprivation and is modulated by estradiol only in neurons from female mice.

The volatile anesthetic, isoflurane, can protect the brain if administered before an insult such as an ischemic stroke. However, this protective "preconditioning" response to isoflurane is specific to...

Peroxisome proliferator activated receptor (PPAR)-γ co-activator 1-α and hypoxia induced factor-1α mediate neuro- and vascular protection by hypoxic preconditioning in vitro.

Preconditioning-induced cellular adaptation is a new therapeutic strategy for ischemic stroke. This research aims to examine the role of peroxisome proliferator activated receptor (PPAR)-γ co-activat...