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Administer tranexamic acid early to injured patients at risk of substantial bleeding

Key pointsGive tranexamic acid to trauma patients at risk of major haemorrhage as early as possible, but not at all if three hours have passed since injury Incorporate tranexamic acid into protocols.....

Tranexamic acid safe in severe trauma, study suggests

Patients with traumatic bleeding can be treated safely with tranexamic acid regardless of the severity of their injuries, according to research...

Tranexamic acid looks promising during emergency surgery

Cochrane Database Syst Rev2013;1:CD010245Tranexamic acid is an antifibrinolytic agent that helps control bleeding in trauma patients and in those scheduled for high risk elective surgery. Tranexamic.....

Cryoprecipitate plus tranexamic acid boost war injury survival

Administration of cryoprecipitate and tranexamic acid significantly improves the likelihood of survival among seriously injured patients requiring packed red blood cells, suggest results from MATTERS...

Hundreds more bleeding trauma patients could be saved if tranexamic acid was used more widely

The clot stabilizer drug tranexamic acid can be administered safely to a wide range of patients with traumatic bleeding and should not be restricted to the most severe cases, a study published in the...

Tranexamic acid may cut blood loss in percutaneous nephrolithotomy

NEW YORK (Reuters Health) - The antifibrinolytic drug tranexamic acid helped reduce blood loss in percutaneous nephrolithotomy (PCNL) in a recent randomized trial.

Hundreds more bleeding trauma patients could be saved if tranexamic acid was used more widely, study suggests

The clot stabilizer drug tranexamic acid can be administered safely to a wide range of patients with traumatic bleeding and should not be restricted to the most severe cases, a new study suggests.

Knee surgery blood loss reduced with single tranexamic acid dose

A single intraoperative dose of tranexamic acid is effective at reducing blood loss in patients undergoing minimally invasive total knee arthroplasty, research suggests.

Hypersensitivity to tranexamic acid: a wide spectrum of adverse reactions.

Cases description This is a retrospective study, based on analysis of data from patients with previous adverse drug reactions admitted to the Allergy and Clinical Immunology Division of both the Unive...

Local use of tranexamic acid in ENT surgery.

Bleeding is a main complication in ENT surgery especially in oral and nasal interventions. Based on good results in local application of tranexamic acid after dental extraction, the different possibil...

Efficacy of tranexamic acid in the treatment of idiopathic and non-functional heavy menstrual bleeding: A systematic review.

Objective. To evaluate the efficacy of tranexamic acid in the treatment of idiopathic and non-functional heavy menstrual bleeding. Design. Systematic review. Population: Women with diagnosis of idiopa...

Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.

Background and purpose Previous studies have shown that either fibrin spray or tranexamic acid can reduce blood loss at total hip replacement, but the 2 treatments have not been directly compared. We...

Efficacy and safety of oral tranexamic acid in women with heavy menstrual bleeding and fibroids.

Aim: To evaluate the efficacy and safety of oral, modified-release tranexamic acid in women with heavy menstrual bleeding and fibroids. Materials & methods: This was a pooled analysis of two pivotal P...