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Search Results for "Treatmant Induced Damage Micro"

17:11 EDT 22nd May 2013 | BioPortfolio

Original Source: Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B

Responses to anticancer therapy are hampered by several factors, and Peter S. Nelson and colleagues here identify a protective effect of the tumor microenvironment. After cytotoxic chemotherapy, inflammatory NF-κB signaling activates the secretion o...

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Damage

Oxidative damage

Anesthesia

Anesthesia is the loss of feeling or sensation in all or part of the body. It may result from damage to nerves or can be induced by an anesthetist (a medical professional) using anesthetics such as...

Pain

Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in term...

Clostridium difficile Induced Diarrhea

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Micro Strategies Recognized as Ingram Micro IBM System x 2012 U.S. Partner of the Year

NEW YORK, March 8, 2013 /PRNewswire/ --Micro Strategies today announced it has been named 2012 IBM System x U.S. Partner of the Year by the world's largest technology distributor Ingram Micro Inc....

Ketone Bodies to Protect Tissues from Damage by Ionizing Radiation

The invention relates to methods of using ketogenic compounds to protect against the adverse effects of radiation exposure, including ionizing radiation tissue damage. NIH inventors have discovered t...

Scientists discover melanoma-driving genetic changes caused by sun damage

(University of Texas M. D. Anderson Cancer Center) It's been a burning question in melanoma research: tumor cells are full of ultraviolet-induced genetic damage caused by sunlight exposure, but which...

Stra6, a retinoic acid-responsive gene, participates in p53-induced apoptosis after DNA damage

Experimental arthritis: JAK inhibition with tofacitinib curbs RANKL-induced joint damage

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

New insight into grape seed extract as a therapeutic and preventative measure to fight obesity-induced kidney damage is presented in a new study. Grape seed and skin extract (GSSE) is known to contain...

High-density lipoproteins limit neutrophil-induced damage to the blood–brain barrier in vitro

Scientists discover genetic changes caused by sun damage

Tumorous cancer cells are full of ultraviolet-induced genetic damage caused by sunlight exposure, but which mutations drive this cancer? By creating a method to spot the changes, scientists from se...

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Evaluation of drug toxicity with hepatocytes cultured in a micro-space cell culture system.

A micro-space cell culture system was recently developed in which cells such as hepatocytes can be cultured and formed into a multicellular three-dimensional (3D) architecture. In this study, we asses...

2-Aminopurine hairpin probes for the detection of ultraviolet-induced DNA damage.

Nucleic acid exposure to radiation and chemical insults leads to damage and disease. Thus, detection and understanding DNA damage is important for elucidating molecular mechanisms of disease. However,...

Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis.

ABSTRACT: INTRODUCTION: Osteoporosis (OP) increases cartilage damage in a combined rabbit model of OP and osteoarthritis (OA). Accordingly, we assessed whether microstructure impairment at subchondral...

A multiparameter approach to monitor disease activity in collagen-induced arthritis.

ABSTRACT: INTRODUCTION: Disease severity in collagen-induced arthritis (CIA) is commonly assessed by clinical scoring of paw swelling and histological examination of joints. Although this is an accura...

ERK mediates anti-apoptotic effect through phosphorylation and cytoplasmic localization of p21(Waf1/Cip1/Sdi) in response to DNA damage in normal human embryonic fibroblast (HEF) cells.

Since anti-apoptotic effect of ERK has not been elucidated clearly in DNA-damage-induced cell death, the role of ERK was examined in normal HEF cells treated with mild DNA damage using etoposide or ca...

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