Drug Approvals

In order to become availible to pateints, drugs need to undergo a number of phases of clinical trials to test their efficacy and safty and to then be authorised by the drug approval organistion in e...

Bcl-2 Antisense Drug

CMV Antisense Drug

Drug Discovery - news, views, blogs and reports

In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed. In the past most drugs have been discovered either by identi...

Minimizing drug interactions

BioSeeker - Triple Analysis Reports - Triple Analysis: Breast Cancer, Colorectal Cancer and Peptides

This triple analysis focuses on cancer drug development strategies in both Breast Cancer and Colorectal Cancer and by the compound strategy of Peptides. Each of these three individual parts is evaluat...

FDA Seeks to Speed Drug Development for Early-Stage, Triple-Negative Breast Cancer

In order to speed the availability of promising drugs for high-risk, early-stage breast cancer, the US Food and Drug Administration (FDA) has drafted new guidelines for clinical trials. These guidelin...

Anti-Copper Drug Might Prevent Organ Metastasis in Triple-Negative Breast Cancer

An anti-copper drug compound that disables the ability of bone marrow cells from setting up a "home" in organs to receive and nurture migrating cancer tumor cells has shown surprising benefit in one o...

Bleeds in Triple Therapy May Hinge on Drug Choice (CME/CE)

(MedPage Today) -- Substituting prasugrel (Effient) for clopidogrel (Plavix) in stented patients on triple therapy may increase the risk of bleeding, researchers found.

Triple Analysis: Apoptosis, Angiogenesis and Peptides

This triple analysis focuses on cancer drug development strategies by the two mechanism/target/effect areas of Apoptosis and Angiogenesis and by the compound strategy of Peptides. Each of these three...

Triple drug combo increases acute kidney injury risk

A triple combination of blood pressure drugs and anti-inflammatories increases the risk of acute kidney injury by almost a third, a new Canadian study has revealed.

Triple Analysis: Angiogenesis, Antibodies and Peptides

This triple analysis focuses on cancer drug development strategies by the mechanism/target/effect of Angiogenesis and by the two compound strategies of Antibodies and Peptides. Each of these three ind...

Genomic sequencing reveals therapeutic drug targets for metastatic triple-negative breast cancer

Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Resea...

Conversion of Ctriple bondC to CO in alkynyl-metal complexes: oxidation of carbon chains capped by carbon-tricobalt clusters.

Treatment of Co(3)(mu(3)-CC[triple bond]CR)(mu-dppm)(CO)(7) with O(2) (air) in the presence of [FcH]PF(6) afforded Co(3){mu(3)-CC(O)R}(mu-dppm)(CO)(7) by the formal conversion -C[triple bond]C- + O-O...

Location of pharmaceutical innovation: 2000-2009.

Interpreting Null Results from Measurements with Uncertain Correlations: An Info-Gap Approach.

Null events-not detecting a pernicious agent-are the basis for declaring the agent is absent. Repeated nulls strengthen confidence in the declaration. However, correlations between observations are di...

Quadruple-drug therapy was better than triple-drug therapy for eradicating Helicobacter pylori in adults.

1-Borabenzonitrile (B-cyanoboratabenzene).

The reaction of 1-chloro-2-(trimethylsilyl)-1-boracyclohexa-2,5-diene with [(n)Bu(4)N]C[triple bond, length as m-dash]N provides the 1-borabenzonitrile salt [(n)Bu(4)N][C(5)H(5)BC[triple bond, length...