Search Results for "Ulcerative Colitis Paxillin"
Original Source: Involvement of beta1-integrin via PIP complex and FAK/paxillin in dexamethasone-induced human mesenchymal stem cell migration.
Although glucocorticoids strongly affect numerous biological processes including cell growth, development, and homeostasis, their effects on migration of human mesenchymal stem cells (hMSCs) are unclear. Therefore, we investigated the role of dexamethasone (DEX) and its related signaling pathways on migration of hMSCs. We found that DEX, at 10(-8) to 10(-6)M, significantly increased migration after a 24 hr incubation, and DEX (10(-6)M) increased migration at > 12 hr. Moreover, DEX (10(-6)M) increased the le...
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Ulcerative colitis is a disease that affects around 120,000 people in the UK and causes inflammation of the large intestine - or colon. Symptoms vary in severity from pain and discomfort, through mu...
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Ulcerative colitis: UCCIS—a reproducible tool to assess mucosal healing
In an attempt to better characterize mucosal healing in ulcerative colitis, various endoscopic scoring systems have been introduced. However, most have limited interobserver agreement. A recent study...
Ulcerative colitis: Paediatric ulcerative colitis—can we predict proctocolectomy?
Given the early onset of ulcerative colitis in children, it is desirable to identify young patients with this disease who are at risk of adverse outcomes. Identification of these patients would enable...
As one of the few probiotics with medical food designation for specific illnesses, VSL#3® has been the subject of a collection of more than 80 studies that have demonstrated its use in the dietary ma...
FIT in shape for new role in ulcerative colitis monitoring
Fecal immunochemical tests could allow noninvasive assessment of patients with ulcerative colitis, say the authors of a Japanese study.
Ulcerative Colitis, Smoking, and Nicotine Therapy
Smoking has been shown to help patients with ulcerative colitis and to offer protective effects. How exactly does it work as a therapeutic agent? Alimentary Pharmacology & Therapeutics
Ulcerative Colitis: Weekend Surgery Adds Complication Risk
Patients with ulcerative colitis who are hospitalized on the weekends have increased risks for several postoperative complications. Medscape Medical News
Ulcerative colitis: Steroid-refractory ulcerative colitis—ciclosporin or infliximab?
Ciclosporin and infliximab are used as rescue therapies for the treatment of severe steroid-refractory ulcerative colitis. Now, an open-label, head-to-head randomized controlled trial has demonstrated...
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Ulcerative colitis: Adalimumab promotes clinical remission in patients with ulcerative colitis.
Is Indeterminate Colitis Determinable?
About 10% of patients with colitis due to inflammatory bowel disease have indeterminate colitis. Despite newer diagnostic tools, the frequency has not diminished over the past 33 years. The current p...
BACKGROUND: Patients with ulcerative colitis often receive thiopurines as immunomodulators (IMs) to maintain remission and avoid corticosteroids. If unresponsive or intolerant to these agents, patient...
