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Original Source: Polarity-switching top coats enable orientation of sub-10-nm block copolymer domains.
Block copolymers (BCPs) must necessarily have high interaction parameters (χ), a fundamental measure of block incompatibility, to self-assemble into sub-10-nanometer features. Unfortunately, a high χ often results from blocks that have disparate interfacial energies, which makes the formation of useful thin-film domain orientations challenging. To mitigate interfacial forces, polymers composed of maleic anhydride and two other components have been designed as top coats that can be spin-coated from basic a...
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Farewell to TQT studies, new webinar hosted by Xtalks
Toronto, Canada (PRWEB) January 24, 2013 As requirements for cardiac studies tighten, the ICH-E14 guideline is essentially mandated for Thorough QT studies. However, these studies are expensive...
Peroxidasin: Tying the collagen-sulfilimine knot
Type IV collagen, a major constituent of basement membranes, contains an unusual intermolecular sulfilimine crosslink whose route of biosynthesis has remained undefined. An oxidative triad consisting...
Investigators Review Studies on Treatment of Klebsiella Pneumoniae Carbapenemase Infections
The emergence of Klebsiella pneumoniae carbapenemases (KPCs) producing bacteria has become a significant global public health challenge while the optimal treatment remains undefined. Lee and Burgess (...
Glucose-Insulin-Potassium for Suspected Acute Myocardial Infarction—Reply
In Reply: We agree with the interpretation of Dr Chaudhuri and colleagues about the beneficial effects seen with GIK in the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Tre...
T-helper-1-cell cytokines drive cancer into senescence
Cancer control by adaptive immunity involves a number of defined death and clearance mechanisms. However, efficient inhibition of exponential cancer growth by T cells and interferon-γ (IFN-γ) requir...
Kismet Jardin Bridges Alchemy of the Past to the Scientific Advancements of the Present in Perfumery
Kismet Jardin is bridging the mystery and beauty of pure natural ingredients and alchemical processes of the past to the scientific advancements of the present in Perfumery...
World Lupus Day Calls Attention to the Global Impact of the "Cruel Mystery"
WASHINGTON, May 9, 2013 /PRNewswire-USNewswire/ -- The Lupus Foundation of America and lupus organizations around the globe are rallying together on May 10, World Lupus Day, to urge action and ra...
New Type of Stem Cell Preparation Could Bring Pain Relief to Diabetics
A new study released today in STEM CELLS Translational Medicine shows the potential of a new approach in preparing stem cells that provide relief to people suffering from a common, yet painful diabete...
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Background/Aims: β(S)-Haplotype prevalence and its associations with clinical and hematological characteristics were assessed in Brazilian children with sickle cell anemia or Sβ(0)-thalassemia. Meth...
OBJECTIVES:Studies from the 1990s through mid-2000s report variable decreases in upper gastrointestinal (UGI) complications and differ regarding changes in lower gastrointestinal (LGI) complications....
ACE inhibitors and ribavirin-associated cough: a common undefined predisposing factor?
Developmental plasticity of stem cells and diseases.
Stem cells, which reside in most tissues with high plasticity of self-renewal and differentiation, play a critical role in the development and maintenance processes of many tissues. It is reasonable t...
Two cases of atypical Whipple's disease associated with cytoplasmic ANCA of undefined specificity.
