None

AAPS PharmSciTech: Thermoreversible Nasal In situ Gel of Venlafaxine Hydrochloride: Formulation, Characterization, and Pharmacodynamic Evaluation

Type: Original PaperIn order to improve the bioavailability of the antidepressant drug, venlafaxine hydrochloride, in situ mucoadhesive thermoreversible gel, was formulated using Lutrol F127 (18%) as...

Interaction between polymorphisms in serotonin transporter (SLC6A4) and serotonin receptor 2A (HTR2A) genes predict treatment response to venlafaxine XR in generalized anxiety disorder

Effexor May Not Mix with Tamoxifen

(MedPage Today) -- SAN ANTONIO - The antidepressant venlafaxine (Effexor), often given to breast cancer patients to treat the hot flashes associated with tamoxifen therapy, might reduce the effectiven...

Antidepressants Safe, Effective for All Depression Types

A reanalysis of the RCTs of fluoxetine and venlafaxine shows the drugs decrease suicidal thoughts and behavior in adults and geriatric patients and that they are effective in less severe depression....

Use of venlafaxine in Austria after introduction of generics

Trying to reduce expenditure on medicine is a major driving force for reforms by many governments. This includes Austria, where measures have been introduced to lower generics prices and enhance their...

Film review: Side effects

A film that will satisfy those of us who prescribe and dispense medicines Benedict Lam reviews a film, the subject of which most pharmacists will identify with: side effects of medication and the p...

Pfizer Announces Top-Line Efficacy Results From A Phase 4 Study Of PRISTIQ® (desvenlafaxine) For The Treatment Of Major Depressive Disorder (MDD) In Adults

Pfizer Inc. (NYSE: PFE) announced today that a Phase 4 study evaluating the efficacy of PRISTIQ® (desvenlafaxine) Extended Release Tablets met its primary endpoint. The study sup...

Mylan Confirms First-to-File Patent Challenge Relating to Pristiq® Tablets

PITTSBURGH, June 28, 2012 /PRNewswire/ -- Mylan Inc. (Nasdaq: MYL) today confirmed that the company has been sued by Pfizer Inc., Wyeth LLC, Wyeth Pharmaceuticals Inc., and PF Prism C.V. in conne...

The modulation of venlafaxine on cortical activation of language area in healthy subjects with fMRI study.

RATIONALE: Previous studies have shown that selective serotonin reuptake inhibitors, activators of the cortex, apparently improved language functional recovery after brain damage rather than simply af...

Antidepressant-Like Effect of Venlafaxine Is Abolished in mu-Opioid Receptor-Knockout Mice.

Although the opioid system is known to modulate depression-like behaviors, its role in the effects of antidepressants is not yet clear. We investigated the role of mu-opioid receptors (MOPs) in the ef...

Ex vivo permeation characteristics of venlafaxine through sheep nasal mucosa.

Venlafaxine, a dual acting antidepressant is a new therapeutic option for chronic depression. Depression is a common mental disorder associated with the abnormalities in neuronal transport in the brai...

Comparing venlafaxine extended release and fluoxetine for preventing the recurrence of major depression: Results from the PREVENT study.

This secondary analysis from the Prevention of Recurrent Episodes of Depression with Venlafaxine Extended Release (ER) for Two Years (PREVENT) study compared the efficacy of venlafaxine ER and fluoxet...

Lack of a pharmacokinetic drug-drug interaction with venlafaxine extended-release/indinavir and desvenlafaxine extended-release/indinavir.

PURPOSE: To assess the effects of venlafaxine extended-release (XR) capsules and desvenlafaxine extended-release (XR) tablets upon indinavir pharmacokinetic properties when co-ad...