Virulence Factors

Virulence factors are molecules expressed and secreted by pathogens (bacteria, viruses, fungi and protozoa) that enable them to achieve the following: * colonization of a niche in the host (this i...

Tissue Growth Factors BMP 2

The classical tissue factors typically are proteins used for tissue repair and growth stimulation. Among the approved products are the growth factors PDGF, IGF, EGF, BMP and FGF. One of the commercial...

Psychosocial factors

Genetic factors

Regulatory factors

Stabilization of cooperative virulence by the expression of an avirulent phenotype

Pathogens often infect hosts through collective actions: they secrete growth-promoting compounds or virulence factors, or evoke host reactions that fuel the colonization of the host. Such behaviours a...

Virulence Profile of Uropathogenic E. Coli in Pakistan

This phylogenetic analysis investigated the distribution of virulence genes and cytotoxic effects of uropathogenic E.coli in order to characterize the local isolates in Pakistan. Annals of Clinical...

Metallothioneins play major role in virulence of Cryptococcus neoformans

Metallothioneins, proteins able to capture metal ions, play a major role in the virulence of Cryptococcus neoformans, a fungal pathogen which causes severe infections in immunodeficient and immunocomp...

Pathogen turns protein into a virulence factor in one easy step

To infect its host, the respiratory pathogen Pseudomonas aeruginosa takes an ordinary protein usually involved in making other proteins and adds three small molecules to turn it into a key for gaining...

Lab Notes: Disarming Darth Vader

(MedPage Today) -- Removing virulence factors from pathogenic bacteria could be a new way to fight infections, by taming rather than killing them. Also: thanks to epigenetics, learned behaviors may be...

Pathogen turns protein into a virulence factor in 1 easy step

(American Society for Microbiology) To infect its host, the respiratory pathogen Pseudomonas aeruginosa takes an ordinary protein usually involved in making other proteins and adds three small molecul...

Cigarette smoke boosts virulence in Staphylococcus aureus

Exposure to cigarette smoke has long been associated with increased frequency of respiratory infections—which are harder to treat in smoke-exposed people than in those who lack such exposures. Now R...

Fucose sensing regulates bacterial intestinal colonization

The mammalian gastrointestinal tract provides a complex and competitive environment for the microbiota. Successful colonization by pathogens requires scavenging nutrients, sensing chemical signals, co...

Cyt toxin expression reveals an inverse regulation of insect and plant virulence factors of Dickeya dadantii.

Summary The plant pathogenic bacteria Dickeya dadantii is also a pathogen of the pea aphid Acyrthosiphon pisum. The genome of the bacteria contains four cyt genes, encoding homologues of Bacillus thur...

Phenotypic characterization and putative virulence factors of human, animal and environmental isolates of Plesiomonas shigelloides.

Plesiomonas shigelloides (a bacterium widely distributed in aquatic ecosystems causing both intestinal and extra-intestinal diseases) shows a host of putative virulence markers, such as hemolysins, cy...

Bacterial Virulence Factors are Associated With Occurrence of Acute Pyelonephritis but Not Renal Scarring.

PURPOSE:: We evaluated the influence of patient factors and virulence factors of uropathogenic Escherichia coli on the occurrence of acute pyelonephritis and subsequent renal parenchymal scarring. MAT...

Comparison of virulence gene profiles of Escherichia coli isolates from sows with coliform mastitis and healthy sows.

Coliform mastitis (CM) is not only a serious economical and animal welfare touching problem in dairy cattle, but also in sows after farrowing. Due to this disease, the essential adequate supply with c...

A secretome-based methodology may provide a better characterization of the virulence of Listeria monocytogenes: preliminary results.

Four strains of Listeria monocytogenes with different levels of virulence were studied. Two strains were consistently evaluated as virulent (strain 3077) and of low virulence (strain 3993), whereas th...