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Search Results for "Vitamin D3 And Its Metabolites Determination"

02:52 EDT 20th May 2013 | BioPortfolio

Original Source: Quantitative determination of vitamin D metabolites in plasma using UHPLC-MS/MS.

Vitamin D is an important determinant of bone health at all ages. The plasma concentrations of 25-hydroxy vitamin D (25-OH D) and other metabolites are used as biomarkers for vitamin sufficiency and function. To allow for the simultaneous determination of five vitamin D metabolites, 25-OH D(3), 25-OH D(2), 24,25-(OH)(2) D(3), 1,25-(OH)(2) D(3), and 1,25-(OH)(2) D(2), in low volumes of human plasma, an assay using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was establi...

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Determination of a specific causative disorder

Vitamin E Deficiency

Frank vitamin E deficiency is rare and overt deficiency symptoms have not been found in healthy people who obtain little vitamin E from their diets. Premature babies of very low birth weight (<1,...

Vitamin B12

Vitamin A

Vitamin C

Vitamin C is a water-soluble vitamin that is necessary to form collagen; so is implicated in the synthesis of skin, scar tissue, tendons, ligaments, and blood vessels, the healing of wounds, and for...

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MR1 presents microbial vitamin B metabolites to MAIT cells

The structure of the major histocompatibility complex (MHC) class I-like molecule MR1 in complex with a vitamin B9 derivative is determined; metabolites of vitamin B2 are shown to activate MR1-restric...

Pharmaceutical Research: Nano-encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation

Type: Original PaperPurposeCalcitriol (1,25-dihydroxyvitamin D3), the active metabolite of vitamin D3, is a potential anticancer agent but with high risk of hypercalcemia which limits the achievement...

Diabetes: Effect of vitamin D on diabetic kidney disease in T1DM

Low circulating levels of vitamin D metabolites were found to be associated with development of microalbuminuria in patients with type 1 diabetes mellitus from the DCCT/EDIC study. Could interventions...

Bone: Vitamin D metabolites and fracture healing

Vitamin D not tied to subclinical atherosclerosis in T1DM

(HealthDay)—For individuals with type 1 diabetes, low concentrations of vitamin D metabolites are not associated with an increased risk of subclinical atherosclerosis, according to a study published...

Assessment of 24,25(OH)2D levels does not support FGF23-mediated catabolism of vitamin D metabolites

Link Between Problems With Mineral Metabolism And Kidney Disease Progression

Mineral metabolites reflect prognosis and may be targets for therapy Highlights: In a study of African Americans with kidney disease, levels of mineral metabolites rose over time; those with fas...

Mushrooms can provide as much vitamin D as supplements

Researchers have discovered that eating mushrooms containing Vitamin D2 can be as effective at increasing and maintaining vitamin D levels (25–hydroxyvitamin D) as taking supplemental vitamin D2 or...

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Quantitative determination of vitamin D metabolites in plasma using UHPLC-MS/MS.

Vitamin D is an important determinant of bone health at all ages. The plasma concentrations of 25-hydroxy vitamin D (25-OH D) and other metabolites are used as biomarkers for vitamin sufficiency and f...

Vitamin D and metabolites measurement by tandem mass spectrometry.

The prevalence of vitamin D deficiency in the general population has become a major public health problem. Vitamin D deficiency might have significant consequences not only to bone health but possibly...

Urinary excretion of vitamin K metabolites in term and preterm infants: relationship to vitamin K status and prophylaxis.

Little is known about the metabolic turnover and excretion of vitamin K in healthy newborn infants and the metabolic consequences of prophylactic regimens designed to protect against vitamin K deficie...

Vitamin D(3) metabolites induce osteogenic differentiation in human dental pulp and human dental follicle cells.

Vitamin D(3) metabolites regulate the bone metabolism and 1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)) is known to play an important role in teeth mineralization. However, little is known ab...

The Determination of Arsenic Metabolites in Patients with Newly Diagnosed Acute Promyelocytic Leukemia Treated with Arsenic Trioxide.

ABSTRACT The efficacy of arsenic trioxide (ATO) in the treatment of acute promyelocytic leukemia (APL) is widely accepted. It is necessary to determine the concentration of arsenic since it is a poiso...

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