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Oncogenic BRAF can result from mutations in the BRAF gene, which may cause the protein to become overactive. The most common alteration in the BRAF gene leads to the BRAFV600E mutation. Mutations in...
PASADENA, Calif. (AP) — Eugene Patton, the stagehand who became "Gene Gene the Dancing Machine" on television's "The Gong Show" in the late 1970s, has died.
(Max-Planck-Gesellschaft) Effects of genome interventions depend on the methods used.
(News.com.au) – IS Australia more likely to breed criminals as a result of its historically penal gene pool? Two variations of a gene have been found to play an important role in criminal behavi...
Sotos syndrome is a congenital syndrome that is characterized by varying degrees of mental retardation and a large head circumference etc. It is known that 90% of Sotos syndrome patients have mutation...
New methods for modifying the genome are currently widely discussed: Using CRISPR/Cas for instance, scientists can remove parts of the genetic code of a gene, thereby knocking it out. Furthermore, the...
Rules of competition Crowding the gene pool There are 33 gene therapy products being developed in Orphan indications where there is more than one competitor developing a therapy encoding the same gene...
Traditionally, to understand how a gene functions, a scientist would breed an organism that lacks that gene then ask how the organism has changed. Are its senses affected? Its behavior? Can it even su...
Testing gene-gene interaction in genome-wide association studies generally yields lower power than testing marginal association. Meta-analysis that combines different genotyping platforms is one metho...
Atrial fibrillation (AF) is the most common cardiac arrhythmia at the clinic. Recent GWAS identified several variants associated with AF, but they account for
To investigate frequency distribution of gene polymorphisms of PRF1 gene in children with hemophagocytic lymphohistiocytosis (HLH), and to explore whether the possible gene polymorphisms of PRF1 gene ...
The glycoprotein-gene (G gene) -deleted rabies virus (RV) vector is a powerful tool to examine the function and structure of neural circuits. We previously reported that the deletion of the G gene enh...
By aggregating data for complex traits in a biologically meaningful way, gene and gene-set analysis constitute a valuable addition to single-marker analysis. However, although various methods for gene...