Search Results for "Warfarin In Vte"

03:20 EDT 29th March 2017 | BioPortfolio

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Vitamin K

Vitamin K is a group of 2-methilo-naphthoquinone derivatives. There are three notable forms of vitamin K; K1 which can be synthesized by plants, K2 which can be formed by natural bacteria in the int...

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AHA 2016: How Do NOAC Drugs Fare Against Well-Managed Warfarin?

Although NOAC drugs compare favorably with warfarin in patients with AF, questions remain about the differences when warfarin is well managed. Dr Mandrola reports on a provocative observational study ...

Warfarin and vitamin K compete for binding to Phe55 in human VKOR

The binding sites for the anticoagulant drug warfarin and for vitamin K on the human VKOR are determined through biochemistry and computational approaches. The results indicate a competitive mechanism...

Performance measures cut costs, improve care in warfarin patients

Not having set guidelines for managing patients on warfarin is costing hospitals and physicians a fortune. Researchers from Boston University School of Medicine (BUSM) have developed new performance m...

New approach to managing warfarin patients improves care, cuts costs

New performance measures have been developed for patients on warfarin that may save lives and money, report investigators.

Bristol-Myers and Pfizer's Eliquis outperforms rivals versus warfarin

In a so-called real world study, the anti-coagulant did better in reducing the risk of strokes or major bleeds compared to warfarin than did J&J's competing Xarelto or Boehringer's&nb...

Nurses using new gene test to personalise warfarin dose

Frontline nurses in Merseyside and Cheshire are pioneering the use of gene testing to prescribe individualised dosages of warfarin.

Genetically guided warfarin dosing lowers risk of some adverse events

Using genetic testing to help personalize doses of warfarin therapy given to patients undergoing elective orthopedic surgery appears to lower the risk of combined adverse events compared with clinical...

Competing risks influence warfarin, thromboembolism link

(HealthDay)—For patients with nonvalvular atrial fibrillation, warfarin is associated with a reduction in thromboembolism, although the correlation is attenuated after accounting for competing death...

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Warfarin-Associated Nonuremic Calciphylaxis.

Classic calciphylaxis associated with renal failure is a life-threatening disease. Warfarin-associated calciphylaxis without renal injury has been described, but whether it is a subset of classic calc...

Novel revelation of warfarin resistant mechanism in roof rats (Rattus rattus) using pharmacokinetic/pharmacodynamic analysis.

Roof rats (Rattus rattus) live mainly in human habitats. Heavy use of rodenticides, such as warfarin, has led to the development of drug resistance, making pest control difficult. There have been many...

Warfarin improves neuropathy in monoclonal gammopathy of undetermined significance.

We report a case of a 60-year-old man who was referred to a palliative care clinic with monoclonal gammopathy of undetermined significance (MGUS)-associated neuropathy, responding to a therapeutic tri...

Integrated analysis of genetic variation and gene expression reveals novel variant for increased warfarin dose requirement in African Americans.

Warfarin is commonly used to control and prevent thromboembolic disorders. However, due to warfarin's complex dose-requirement relationship, safe and effective use is challenging. Pharmacogenomics-gui...

The Impact of Genetic and Non-Genetic Factors on Warfarin Dose Prediction in MENA Region: A Systematic Review.

Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are str...

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