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Search Results for "Warfarin In Vte"

08:20 EST 20th February 2017 | BioPortfolio

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Vitamin K

Vitamin K is a group of 2-methilo-naphthoquinone derivatives. There are three notable forms of vitamin K; K1 which can be synthesized by plants, K2 which can be formed by natural bacteria in the int...

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AHA 2016: How Do NOAC Drugs Fare Against Well-Managed Warfarin?

Although NOAC drugs compare favorably with warfarin in patients with AF, questions remain about the differences when warfarin is well managed. Dr Mandrola reports on a provocative observational study ...

Warfarin and vitamin K compete for binding to Phe55 in human VKOR

The binding sites for the anticoagulant drug warfarin and for vitamin K on the human VKOR are determined through biochemistry and computational approaches. The results indicate a competitive mechanism...

Performance measures cut costs, improve care in warfarin patients

Not having set guidelines for managing patients on warfarin is costing hospitals and physicians a fortune. Researchers from Boston University School of Medicine (BUSM) have developed new performance m...

Larger TAVR Valves May Predispose to Clot, but Will Warfarin Help?

Warfarin alone or with antiplatelet therapy may protect against thrombosis after transcatheter aortic-valve replacement, but not everyone agrees there is enough support for anticoagulants yet. Heart...

Novel Anticoagulants or Warfarin for AF?

The meta-analysis included four phase III clinical trials comparing novel anticoagulants to warfarin in patients with atrial fibrillation.

New approach to managing warfarin patients improves care, cuts costs

New performance measures have been developed for patients on warfarin that may save lives and money, report investigators.

Warfarin persistence higher than previously reported in A-fib

(HealthDay)—Among patients with atrial fibrillation (AF), the proportion of warfarin persistence is 0.91 at one year and 0.73 at four years, according to a study published online Aug. 27 in Cardiova...

New drugs offer alternative to warfarin for treating stroke

Warfarin has remained a top drug therapy for the prevention of stroke for decades, but recent advancements in oral anticoagulants may provide more effective and safer treatment options. 

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Warfarin-Associated Nonuremic Calciphylaxis.

Classic calciphylaxis associated with renal failure is a life-threatening disease. Warfarin-associated calciphylaxis without renal injury has been described, but whether it is a subset of classic calc...

Novel revelation of warfarin resistant mechanism in roof rats (Rattus rattus) using pharmacokinetic/pharmacodynamic analysis.

Roof rats (Rattus rattus) live mainly in human habitats. Heavy use of rodenticides, such as warfarin, has led to the development of drug resistance, making pest control difficult. There have been many...

Warfarin improves neuropathy in monoclonal gammopathy of undetermined significance.

We report a case of a 60-year-old man who was referred to a palliative care clinic with monoclonal gammopathy of undetermined significance (MGUS)-associated neuropathy, responding to a therapeutic tri...

Integrated analysis of genetic variation and gene expression reveals novel variant for increased warfarin dose requirement in African Americans.

Warfarin is commonly used to control and prevent thromboembolic disorders. However, due to warfarin's complex dose-requirement relationship, safe and effective use is challenging. Pharmacogenomics-gui...

In silico evaluation of warfarin-bucolome therapy.

Some reports have suggested that bucolome, an inhibitor of cytochrome P450 2C9, is useful for decreasing inter-patient variation in warfarin clearance. The purpose of the present study was to evaluate...

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