Search Results for "Warfarin In Vte"

11:20 EST 18th January 2017 | BioPortfolio

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Vitamin K

Vitamin K is a group of 2-methilo-naphthoquinone derivatives. There are three notable forms of vitamin K; K1 which can be synthesized by plants, K2 which can be formed by natural bacteria in the int...

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AHA 2016: How Do NOAC Drugs Fare Against Well-Managed Warfarin?

Although NOAC drugs compare favorably with warfarin in patients with AF, questions remain about the differences when warfarin is well managed. Dr Mandrola reports on a provocative observational study ...

Warfarin and vitamin K compete for binding to Phe55 in human VKOR

The binding sites for the anticoagulant drug warfarin and for vitamin K on the human VKOR are determined through biochemistry and computational approaches. The results indicate a competitive mechanism...

Performance measures cut costs, improve care in warfarin patients

Not having set guidelines for managing patients on warfarin is costing hospitals and physicians a fortune. Researchers from Boston University School of Medicine (BUSM) have developed new performance m...

Larger TAVR Valves May Predispose to Clot, but Will Warfarin Help?

Warfarin alone or with antiplatelet therapy may protect against thrombosis after transcatheter aortic-valve replacement, but not everyone agrees there is enough support for anticoagulants yet. Heart...

Novel Anticoagulants or Warfarin for AF?

The meta-analysis included four phase III clinical trials comparing novel anticoagulants to warfarin in patients with atrial fibrillation.

Warfarin INR Instability Common, Supports Shift to NOACs: Study

At least a third of patients on warfarin had INR values that were off, not "just slightly out of range" but "significantly out of range," an author says. Heartwire from Medscape

Stability of International Normalized Ratios With Long-term Warfarin Therapy

This cohort study uses data from an atrial fibrillation registry to describe the proportion of patients on warfarin who had stable INR values over an 18-month period.

New approach to managing warfarin patients improves care, cuts costs

New performance measures have been developed for patients on warfarin that may save lives and money, report investigators.

Matching PubMed Articles

Novel revelation of warfarin resistant mechanism in roof rats (Rattus rattus) using pharmacokinetic/pharmacodynamic analysis.

Roof rats (Rattus rattus) live mainly in human habitats. Heavy use of rodenticides, such as warfarin, has led to the development of drug resistance, making pest control difficult. There have been many...

Warfarin improves neuropathy in monoclonal gammopathy of undetermined significance.

We report a case of a 60-year-old man who was referred to a palliative care clinic with monoclonal gammopathy of undetermined significance (MGUS)-associated neuropathy, responding to a therapeutic tri...

In silico evaluation of warfarin-bucolome therapy.

Some reports have suggested that bucolome, an inhibitor of cytochrome P450 2C9, is useful for decreasing inter-patient variation in warfarin clearance. The purpose of the present study was to evaluate...

The Impact of Genetic and Non-Genetic Factors on Warfarin Dose Prediction in MENA Region: A Systematic Review.

Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are str...

Elevated International Normalized Ratio in a Patient Taking Warfarin and Mauby: A Case Report.

We describe a 70-year-old Haitian man who had been taking warfarin for 5 years for atrial fibrillation and pulmonary hypertension. This patient had his international normalized ratio (INR) checked in ...

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