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APP buys three injectable products from Nexus

APP Pharmaceuticals, a Fresenius Kabi Company, has purchased three products, Benztropine Mesylate Injection, Levetiracetam Injection and Tranexamic Acid Injection, from Nexus Pharmaceuticals.

APP Pharmaceuticals Acquires Three Products from Nexus

APP Pharmaceuticals, LLC, a Fresenius Kabi Company, today announced it has acquired three products from Nexus Pharmaceuticals, Inc. Under terms of the agreement APP takes complete...

Akorn Reports Third Quarter 2012 Financial Results

Akorn, Inc. (NASDAQ: AKRX), a niche generic pharmaceutical company, today reported financial results for the third quarter of 2012. Third Quarter Highlights...

Synergism of theophylline and anticholinergics to inhibit haloperidol-induced catalepsy: A potential treatment for extrapyramidal syndromes.

Extrapyramidal syndromes (EPS) impose a heavy burden on patients receiving antipsychotic therapy. Anticholinergics are the drugs of choice for preventing EPS, but they also produce many adverse reacti...

DOPAMINE TRANSPORTER-DEPENDENT AND -INDEPENDENT STRIATAL BINDING OF THE BENZTROPINE ANALOG JHW 007, A COCAINE ANTAGONIST WITH LOW ABUSE LIABILITY.

The benztropine analog JHW 007 displays high affinity for the dopamine transporter (DAT), but unlike typical DAT ligands, has relatively low abuse liability and blocks effects of cocaine, including it...

The stereotypy-inducing effects of N-substituted benztropine analogs alone and in combination with cocaine do not account for their blockade of cocaine self-administration.

RATIONALE: Previous studies have demonstrated that several N-substituted 4', 4″-diF-benztropine (BZT) analogs with high dopamine transporter affinity selectively decreased cocaine self-administratio...

Evaluation of postmortem redistribution phenomena for commonly encountered drugs.

We described the findings of a study into the post-mortem redistribution (PMR) of 76 drugs found in 129 drug-related cases between 2006 and 2009. Seventy six drugs (psychotropic drugs (n=14), antidepr...

Pharmacokinetics of the long-acting, first-generation antipsychotic fluphenazine.

Abstract Despite the advantages of second-generation antipsychotics, effectiveness trials and cost-effective analyses have caused first-generation antipsychotics to be reexamined with regard to place...