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Search Results for "What Is Lambda Z In Pharmacokinetics"

12:16 EDT 24th April 2014 | BioPortfolio

Original Source: Pharmacokinetics and bioavailability of a long-acting formulation of cephalexin after intramuscular administration to cats.

The pharmacokinetic profile and bioavailability of a long-acting formulation of cephalexin after intramuscular administration to cats was investigated. Single intravenous (cephalexin lysine salt) and intramuscular (20% cephalexin monohydrate suspension) were administered to five cats at a dose rate of 10mg/kg. Serum disposition curves were analyzed by noncompartmental approaches. After intravenous administration, volume of distribution (V(z)), total body clearance (Cl(t)), elimination constant (lambda(z)),...

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Pharmacokinetics

macitentan

Macitentan (Opsumit®) is a novel dual endothelin receptor antagonist (ERA) that resulted from a tailored drug discovery process with the target to develop an ERA optimized for efficacy and safet...

Serine Threonine protein kinase C PKC

The serine/threonine protein kinase C (PKC) family consists of at least 11 mammalian isozymes belonging to a larger subclass of protein kinases termed the adenine-guanine-cytosine (AGC) kinases. PK...

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Agilux Laboratories expands in vivo pharmacokinetics services

New England-based CRO Agilux Laboratories, a provider of drug metabolism and pharmacokinetics (DMPK) services to sponsors, has expanded its in vivo pharmacokinetics services to support clients' demand...

Agilux Laboratories announces space expansion of its in vivo pharmacokinetics services

Agilux Laboratories, a provider of drug metabolism and pharmacokinetics (DMPK) services to pharmaceutical and biotechnology firms, has announced that it has undergone a significant space expansion of...

PEG-IFN lambda: Phase IIb data

Etanercept biosimilar has comparable pharmacokinetics to Enbrel

An etanercept biosimilar (CHS-0214) from fledgling biotech company Coherus Biosciences (Coherus) has shown comparable pharmacokinetics in a pivotal clinical study.

UPDATE 1-Obamacare insurers in Louisiana delay HIV policy change

(New throughout; adds latest court ruling, Blue Cross, Lambda comments)

Precision Optics Help Push the Boundaries of High Resolution FT-IR

Optical Surfaces Ltd. has been selected by a leading spectrophotometer manufacturer to supply ultra high precision matched beamsplitter / compensator optics for the interferometer that lies at the hea...

Intra-Cellular Therapies initiates Phase I/II clinical trial to evaluate pharmacokinetics in patients with dementia

Intra-Cellular Therapies, Inc., a biopharmaceutical company focused on the development of therapeutics for central nervous system (CNS) disorders, today announced the initiation of ITI-007-200, a Phas...

Provectus announces PV-10's assessment for drug-drug interaction potential

Provectus Biopharmaceuticals, Inc., a development-stage oncology and dermatology biopharmaceutical company, and XenoTech, a preclinical CRO and pioneer in collaborative research surrounding in vitro d...

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Helicobacter pylori Infection and Light Chain Gammopathy.

Objective. Helicobacter pylori provokes a host of immune alterations upon colonizing the gastric mucosa. Design. We report 22 individuals with confirmed Helicobacter pylori infection who were also man...

Type III interferon (IFN-lambda) antagonizes the antiviral activity of interferon-alpha in vitro.

Type III interferons (IFN-lambda) are the most recently discovered members of IFN family. Synergism between different IFN types is well established, but for type I and type III IFNs no conclusive evid...

Determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical preparations using derivative spectrophotometry and chromatographic-densitometric method.

Two methods, spectrophotometric and chromatographic-densitometric ones, were developed for determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical prepar...

Urinary gamma-glutamyl transferase-to-creatinine ratio as an indicator of tubular function in Bence Jones Proteinuria.

Abstract Increased urinary gamma-glutamyl transferase (GGT) activity suggests early renal tubular damage. The aim of this study was to evaluate the urinary GGT activity as a marker of renal injury in...

Application of a Redox Gradostat Reactor for Assessing Rhizosphere Microorganism Activity on Lambda-Cyhalothrin.

Bacterial activity on pesticides can lead to decreased toxicity or persistence in aquatic systems. Rhizosphere activity is difficult to measure in situ. To mimic rhizosphere properties of the soft rus...

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