Search Results for "What Is Lambda Z In Pharmacokinetics"

04:36 EDT 31st August 2014 | BioPortfolio

Original Source: Pharmacokinetics and bioavailability of a long-acting formulation of cephalexin after intramuscular administration to cats.

The pharmacokinetic profile and bioavailability of a long-acting formulation of cephalexin after intramuscular administration to cats was investigated. Single intravenous (cephalexin lysine salt) and intramuscular (20% cephalexin monohydrate suspension) were administered to five cats at a dose rate of 10mg/kg. Serum disposition curves were analyzed by noncompartmental approaches. After intravenous administration, volume of distribution (V(z)), total body clearance (Cl(t)), elimination constant (lambda(z)),...

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Pharmacokinetics

macitentan

Macitentan (Opsumit®) is a novel dual endothelin receptor antagonist (ERA) that resulted from a tailored drug discovery process with the target to develop an ERA optimized for efficacy and safet...

Serine Threonine protein kinase C PKC

The serine/threonine protein kinase C (PKC) family consists of at least 11 mammalian isozymes belonging to a larger subclass of protein kinases termed the adenine-guanine-cytosine (AGC) kinases. PK...

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Peginterferon lambda-1a for hepatitis C

Peginterferon lambda-1a is intended for the treatment of hepatitis C virus (HCV) infection in adult patients who are treatment naïve or have relapsed to prior pegylated alfa interferon, including pat...

PEG-IFN lambda: Phase IIb data

eACH Signs Lambda Solutions Inc. As Platinum Sponsor for Canada's Only eLearning Healthcare Conference

Lambda Solutions is proud to become a Platinum Sponsor to support the conference and be part of this exciting time in the advancement of e-Learning in the healthcare industry. eLearning Alliance of Ca...

Precision Optics Help Push the Boundaries of High Resolution FT-IR

Optical Surfaces Ltd. has been selected by a leading spectrophotometer manufacturer to supply ultra high precision matched beamsplitter / compensator optics for the interferometer that lies at the hea...

BioStatus DRAQ7 far-red fluorescent DNA dye

DRAQ7 is a non-toxic, far-red fluorescent DNA dye that only stains the nuclei in dead and permeabilised cells. The dye does not overlap with PE and homologues, making it a suitable replacement for com...

One Lambda, Inc. and GenoDive Pharma, Inc. Enter Exclusivity Agreement on Long-Range Primers for NGS

One Lambda, Inc. to Develop an In Vitro Diagnostic (IVD) Next-Generation Sequencing (NGS) kit for HLA Genes using Long-Range Primers from GenoDive, Inc. of Japan. One L...

Pharmaceutical Research: Comparison of Succinimidyl [125I]Iodobenzoate with Iodogen Iodination Methods to Study Pharmacokinetics and ADME of Biotherapeutics

Type: Original PaperPurposeTo assess the application of succinimidyl iodobenzoate (SIB) iodination method in labeling biotherapeutics to study their pharmacokinetics (PK) and biodistribution.MethodAn...

Lambda Solutions Inc. and Limestone Learning Partner to Provide Full-Service, Cloud-Based, Talent and Training Development Systems in North America

The strategic partnership will provide current and incoming customers with holistic custom learning materials for the leading open source talent and learning management systems, Moodle and Totara. Van...

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Helicobacter pylori Infection and Light Chain Gammopathy.

Objective. Helicobacter pylori provokes a host of immune alterations upon colonizing the gastric mucosa. Design. We report 22 individuals with confirmed Helicobacter pylori infection who were also man...

Type III interferon (IFN-lambda) antagonizes the antiviral activity of interferon-alpha in vitro.

Type III interferons (IFN-lambda) are the most recently discovered members of IFN family. Synergism between different IFN types is well established, but for type I and type III IFNs no conclusive evid...

Determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical preparations using derivative spectrophotometry and chromatographic-densitometric method.

Two methods, spectrophotometric and chromatographic-densitometric ones, were developed for determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical prepar...

Urinary gamma-glutamyl transferase-to-creatinine ratio as an indicator of tubular function in Bence Jones Proteinuria.

Abstract Increased urinary gamma-glutamyl transferase (GGT) activity suggests early renal tubular damage. The aim of this study was to evaluate the urinary GGT activity as a marker of renal injury in...

Application of a Redox Gradostat Reactor for Assessing Rhizosphere Microorganism Activity on Lambda-Cyhalothrin.

Bacterial activity on pesticides can lead to decreased toxicity or persistence in aquatic systems. Rhizosphere activity is difficult to measure in situ. To mimic rhizosphere properties of the soft rus...

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