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02:30 EDT 27th August 2016 | BioPortfolio

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Pharmacokinetics

macitentan

Macitentan (Opsumit®) is a novel dual endothelin receptor antagonist (ERA) that resulted from a tailored drug discovery process with the target to develop an ERA optimized for efficacy and safet...

Serine Threonine protein kinase C PKC

The serine/threonine protein kinase C (PKC) family consists of at least 11 mammalian isozymes belonging to a larger subclass of protein kinases termed the adenine-guanine-cytosine (AGC) kinases. PK...

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Eiger BioPharma licenses “Lambda” from Bristol-Myers

USA-based Eiger BioPharmaceuticals has licensed Pegylated Interferon Lambda-1a (Lambda), a novel, well-characterized,…

Eiger Biopharma Licenses an Investigational HVD Therapy from BMS

PALO ALTO, Calif., April 20, 2016 /PRNewswire/ — Eiger BioPharmaceuticals, Inc. (NASDAQ: EIGR) announced today that it has licensed Pegylated Interferon Lambda-1a (“Lambda”), a novel...

Lambda appointed new president

Biospectrum Lambda announces the joining of Dr Tausif Monif as President – Global Operations [Read more]

Eiger licenses lambda to investigate potential therapy for hepatitis delta

Eiger BioPharmaceuticals Inc. announced it licensed pegylated interferon lambda-1a to Bristol-Myers Squibb to investigate the efficacy and safety of the drug as a therapeutic option for the treatment ...

Eiger BioPharmaceuticals to Develop BMS' Lambda for HDV

Eiger BioPharmaceuticals said today it has licensed from Bristol-Myers Squibb (BMS) its Pegylated Interferon Lambda-1a, a first-in-class type III interferon, for study as a monotherapy and combinati...

Pharmacokinetics Could Save Maria Sharapova

On May 18, a hearing will commence in London, allowing Sharapova to appeal her provisional suspension for testing positive for meldonium, and pharmacokinetics could end up being her best friend.

BRIEF-Eiger Biopharmaceuticals says license of worldwide rights to Pegylated Interferon lambda-1a from Bristol-Myers Squibb

* Eiger biopharmaceuticals announces license of worldwide rights to pegylated interferon lambda-1a from bristol-myers squibb

Lambda Chi Alpha, in Partnership with Feeding America, Raised More Than 4.4 Million Pounds of Food over the Last Year

CARMEL, Ind., Aug. 17, 2016 (GLOBE NEWSWIRE) -- Lambda Chi Alpha Fraternity, in partnership with Feeding America, raised more than 4.4 million pounds of food during the past year. ...

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Biological trait analysis and stability of lambda-cyhalothrin resistance in the house fly, Musca domestica L. (Diptera: Muscidae).

House flies, Musca domestica L., (Diptera: Muscidae), are pests of poultry and have the ability to develop resistance to insecticides. To design a strategy for resistance management, life history trai...

Peginterferon Lambda-1a/Ribavirin with Daclatasvir or Peginterferon Alfa-2a/Ribavirin with Telaprevir for Chronic Hepatitis C Genotype 1b.

The study objective was to compare the efficacy and safety of peginterferon lambda-1a combined with ribavirin/daclatasvir (Lambda/RBV/DCV), versus peginterferon alfa-2a combined with ribavirin/telapre...

Obesity Does Not Affect Propofol Pharmacokinetics During Hypothermic Cardiopulmonary Bypass.

Because of the lack of data regarding the impact of obesity on propofol pharmacokinetics in patients undergoing cardiac surgery using hypothermic cardiopulmonary bypass (CPB), the authors sought to ex...

Lithium in Paediatric Patients with Bipolar Disorder: Implications for Selection of Dosage Regimens via Population Pharmacokinetics/Pharmacodynamics.

Lithium is a well-established treatment for bipolar I disorder in adults. However, there is a paucity of information on its pharmacokinetics/pharmacodynamics in children and adolescents. We aimed to d...

Association of interferon lambda-1 with herpes simplex viruses-1 and -2, Epstein-Barr virus, and human cytomegalovirus in chronic periodontitis.

Periodontal tissues facilitate the homing of herpes viruses that elicit the immune-inflammatory response releasing the interferons (IFN). IFN lambda-1 (λ1) can suppress the replication of viruses, an...

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