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Search Results for "What Is Lambda Z In Pharmacokinetics"

17:16 EST 5th February 2016 | BioPortfolio

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Pharmacokinetics

macitentan

Macitentan (Opsumit®) is a novel dual endothelin receptor antagonist (ERA) that resulted from a tailored drug discovery process with the target to develop an ERA optimized for efficacy and safet...

Serine Threonine protein kinase C PKC

The serine/threonine protein kinase C (PKC) family consists of at least 11 mammalian isozymes belonging to a larger subclass of protein kinases termed the adenine-guanine-cytosine (AGC) kinases. PK...

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Advanced Moodle LMS Reporting Solution Set to Launch

Vancouver, Canada (PRWEB) August 13, 2015 Lambda Solutions, industry leading innovators in cloud learning management systems, today ...

Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model

Breaking down the complex subject of pharmacokinetics

‘Essential pharmacokinetics: a primer for pharmaceutical scientists’, by Thorsteinn Loftsson.

Lambda Chi Alpha, in Partnership with Feeding America, Raises More than 3.4 Million Pounds of Food during the Fall 2015 Semester

INDIANAPOLIS, Jan. 11, 2016 (GLOBE NEWSWIRE) -- Lambda Chi Alpha Fraternity, in partnership with Feeding America, raised more than 3.4 million pounds of food during the fall 2015 semester, far exceed...

Novimmune and Baxalta ink international bispecific antibody collaboration

GENEVA, SWITZERLAND -- (Marketwired) -- 09/02/15 -- Novimmune SA announced today that it has signed an international research collaboration agreement with Baxalta Incorporated (Baxalta) to develop no...

Novimmune, Baxalta Ink Bispecific Antibody Pact

Will use Novimmune's new kappa-lambda bispecific antibody technology platform

Pharmaceutical Research: A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep

Type: Original PaperPurposeCancer metastasis to pulmonary lymph nodes dictates the need to deliver chemotherapeutic and diagnostic agents to the lung and associated lymph nodes. Drug conjugation to de...

Link found between flaviviruses, peroxisome development

Researchers from the University of Alberta’s Faculty of Medicine and Dentistry have discovered a link between flaviviruses and peroxisome production. According to the study, viruses -- i...

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Evolution of Hematopoietic Cell transplantation for immunoglobulin light chain (AL) amyloidosis.

A 45-year-old male presented to our institution for management of recent diagnosis of lambda light chain AL established on a kidney biopsy that was done to evaluate new onset nephrotic syndrome. The p...

Peginterferon Lambda-1a is Associated with a Low Incidence of Autoimmune Thyroid Disease in Chronic Hepatitis C.

Peginterferon alfa (alfa) increases the risk of autoimmune disease. Peginterferon lambda-1a (Lambda) acts through a receptor with a more liver-specific distribution compared to the alfa receptor. In a...

No influence of CYP2D6*10 genotype and phenotype on the pharmacokinetics of nebivolol in healthy Chinese subjects.

Nebivolol, a clinically important antihypertensive drug, mainly metabolized by cytochrome P450 (CYP) 2D6, shows wide interindividual variability in pharmacokinetics. The CYP2D6*10 allele (100C>T; rs10...

SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid.

Organic anion transporting polypeptide 1B1 (OATP1B1, encoded by SLCO1B1 gene) is a hepatic uptake transporter, and its genetic variability is associated with pharmacokinetics and muscle toxicity risk ...

Roxithromycin Pharmacokinetics in Hospitalized Geriatric Patients: Oral Administration of Whole Versus Crushed Tablets.

Drug administration as tablets to debilitated elderly patients in crushed form can modify the pharmacokinetic characteristics of the active components. Only scarce information is available on the phar...

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