Search Results for "What Is Lambda Z In Pharmacokinetics"

05:02 EDT 4th October 2015 | BioPortfolio

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Macitentan (Opsumit®) is a novel dual endothelin receptor antagonist (ERA) that resulted from a tailored drug discovery process with the target to develop an ERA optimized for efficacy and safet...

Serine Threonine protein kinase C PKC

The serine/threonine protein kinase C (PKC) family consists of at least 11 mammalian isozymes belonging to a larger subclass of protein kinases termed the adenine-guanine-cytosine (AGC) kinases. PK...

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Thermo Fisher's One Lambda introduces new LABScreen Multi IVD test

Thermo Fisher Scientific subsidiary One Lambda has introduced a new LABScreen Multi assay to detect HNA-3 and HLA.

Advanced Moodle LMS Reporting Solution Set to Launch

Vancouver, Canada (PRWEB) August 13, 2015 Lambda Solutions, industry leading innovators in cloud learning management systems, today ...

Learning Management System Reporting & Analytics Launch

Orlando, Florida (PRWEB) May 14, 2015 Lambda Solutions is officially launching their learning management system reporting and analytics solution, Lambda Analytika , at the ATD Conference May 17-20...

Breaking down the complex subject of pharmacokinetics

‘Essential pharmacokinetics: a primer for pharmaceutical scientists’, by Thorsteinn Loftsson.

NASH-linked changes impact metformin pharmacokinetics

(HealthDay)—Nonalcoholic steatohepatitis (NASH)-associated changes in liver function affect kidney transporter expression and metformin pharmacokinetics, according to an experimental study published...

Novimmune and Baxalta ink international bispecific antibody collaboration

GENEVA, SWITZERLAND -- (Marketwired) -- 09/02/15 -- Novimmune SA announced today that it has signed an international research collaboration agreement with Baxalta Incorporated (Baxalta) to develop no...

Novimmune, Baxalta Ink Bispecific Antibody Pact

Will use Novimmune's new kappa-lambda bispecific antibody technology platform

Pharmaceutical Research: The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients Before and One Year After Bariatric Surgery

Type: Original PaperPurposeBariatric surgery is nowadays commonly applied as treatment for morbid obesity (BMI > 40 kg/m2). As information about the effects of this procedure on a drug’s pha...

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Peginterferon Lambda-1a is Associated with a Low Incidence of Autoimmune Thyroid Disease in Chronic Hepatitis C.

Peginterferon alfa (alfa) increases the risk of autoimmune disease. Peginterferon lambda-1a (Lambda) acts through a receptor with a more liver-specific distribution compared to the alfa receptor. In a...

Relationship Between Sunitinib Pharmacokinetics and Administration Time: Preclinical and Clinical Evidence.

Circadian rhythms may influence the pharmacokinetics of drugs. This study aimed to elucidate whether the pharmacokinetics of the orally administered drug sunitinib are subject to circadian variation.

No influence of CYP2D6*10 genotype and phenotype on the pharmacokinetics of nebivolol in healthy Chinese subjects.

Nebivolol, a clinically important antihypertensive drug, mainly metabolized by cytochrome P450 (CYP) 2D6, shows wide interindividual variability in pharmacokinetics. The CYP2D6*10 allele (100C>T; rs10...

Impairment of Type I but Not Type III IFN Signaling by Hepatitis C Virus Infection Influences Antiviral Responses in Primary Human Hepatocytes.

Peginterferon lambda-1a (Lambda), a type III interferon (IFN), acts through a unique receptor complex with limited cellular expression outside the liver which may result in a differentiated tolerabili...

Interferon lambda-3 polymorphism and response to pegylated interferon in patients with hepatitis D.

Specific single nucleotide polymorphisms (SNPs) near the interferon lambda 3 (IFNλ3) gene (formal interleukin 28B), influence the response to treatment with interferon in hepatitis C patients. We aim...

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