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Zoledronate may top alendronate for stopping bone loss after transplant

NEW YORK (Reuters Health) - Zoledronic acid (zoledronate) may be a better choice than alendronate for preventing bone loss after heart or liver transplantation.

Zoledronate Boosts Sclerostin, Which Slows Bone Formation

A small study in women with osteoporosis finds that although zoledronate stops bone loss, it also acts to increase levels of sclerostin, which in turn dampens bone formation. Medscape Medical Ne...

Spore-forming Bacteria Infections in Those Who Inject Drugs

Persons who inject drugs are at risk of outbreaks of illness associated with spore-forming bacteria. Emerging Infectious Diseases

WHO identifies key actions countries can take to prevent HIV infections among people who inject drugs

WHO has identified four key actions countries can take to prevent viral hepatitis B and C among people who inject drugs. Of the estimated 16 million people who inject drugs worldwide, it is estimated...

Methadone reduces risk of HIV transmission in people who inject drugs, say experts

(Medical Xpress)—People who inject drugs (PWID) can significantly reduce their risk of HIV infection with the use of opiate substitution treatments such as methadone, as suggested by an internationa...

Acute Anterior Uveitis After Intravenous Zoledronate

About one in 100 patients could develop acute anterior uveitis (AAU) in the week after receiving intravenous zoledronate, researchers from New Zealand report. Reuters Health Information

Opiate substitution treatment and HIV transmission in people who inject drugs: systematic review and meta-analysis

Objective To quantify the effect of opiate substitution treatment in relation to HIV transmission among people who inject drugs.Design Systematic review and meta-analysis of prospective published and....

Nature’s sexism

The editors of this publication need to improve how we reflect women’s contributions to science. For this, we must inject an extra loop into our thinking.

Short-term effects of zoledronate on the histomorphology of osteoclast in young albino rats.

The present study was conducted to histomorphometrically evaluate the effects of short-term administration of zoledronate, a third generation bisphosphonate, on the metaphysis of the proximal end of t...

Gamma delta T cells from HIV(+) donors can be expanded in vitro by zoledronate/interleukin-2 to become cytotoxic effectors for antibody-dependent cellular cytotoxicity.

Abstract Background aims. Immunotherapy using γδ T cells capable of mediating antibody-dependent cellular cytotoxicity (ADCC) is a promising anti-human immunodeficiency virus (HIV) strategy. Appro...

Surface immobilized zoledronate improves screw fixation in rat bone: A new method for the coating of metal implants.

Previous studies show that surface immobilized bisphosphonates improve the fixation of stainless steel screws in rat tibia after 2-8 weeks of implantation. We report here about the immobilization of...

"Fitness for duty": Social, organisational and structural influences on the design and conduct of candidate hepatitis C vaccine trials involving people who inject drugs.

Several candidate vaccines for hepatitis C are currently in preclinical development or the early stages of clinical trials. Implementing trials of these vaccines among people who inject drugs will be...

Local application of zoledronate for maximum anchorage during space closure.

Orthodontists have used various compliance-dependent physical means such as headgears and intraoral appliances to prevent anchorage loss. The aim of this study was to determine whether 1 local applica...