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17:53 EDT 29th June 2016 | BioPortfolio

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Effect of Continued Treatment With Pirfenidone in IPF

Do idiopathic pulmonary fibrosis patients benefit from continued treatment with pirfenidone -- particularly those who experienced meaningful disease progression during treatment? Thorax

Initiation of first multinational study to evaluate safety of OFEV® (nintedanib) with add-on of pirfenidone in patients with IPF

Kadmon Initiates Phase 2 Clinical Trial Evaluating KD025 in Idiopathic Pulmonary Fibrosis

NEW YORK, NY -- (Marketwired) -- 06/03/16 -- Kadmon Corporation, LLC today announced that the first patient has been dosed in a Phase 2 clinical trial of KD025, the Company's rho-associated coiled-co...

Prothena Announces Appointment of Chief Commercial Officer

DUBLIN, Ireland, Feb. 24, 2016 (GLOBE NEWSWIRE) -- Prothena Corporation plc (NASDAQ:PRTA), a late-stage clinical biotechnology company focused on the discovery, development and commercializatio...

Synairgen PLC and why the market is not the best arbiter of value

If the market worked as perfectly as its more rabid advocates insist, we wouldn’t have attractive anomalies such as Synairgen plc (LON:SNG). Its shares are trading at a fraction of what would be c...

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Efficacy of pirfenidone and disease severity of idiopathic pulmonary fibrosis: Extended analysis of phase III trial in Japan.

A phase III clinical trial of pirfenidone in patients with idiopathic pulmonary fibrosis (IPF) in Japan has revealed that pirfenidone attenuated the decline in vital capacity (VC) and improved progres...

All-case post-marketing surveillance of 1371 patients treated with pirfenidone for idiopathic pulmonary fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease with a median survival of 2-5 years and limited treatment options. In 2008, pirfenidone became the first drug to be approved for ...

A safety evaluation of pirfenidone for the treatment of idiopathic pulmonary fibrosis.

Pirfenidone is a novel oral anti-fibrotic agent approved for the treatment of idiopathic pulmonary fibrosis (IPF). Since IPF is a chronic and progressive disease most commonly encountered in an older ...

Therapeutic advances in Idiopathic Pulmonary Fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a primary lung disorder that scars distal airspaces and has a prognosis similar to many aggressive cancers. After decades of failed clinical trials, two drugs (n...

Risk factors for acute exacerbation of idiopathic pulmonary fibrosis - Extended analysis of pirfenidone trial in Japan.

Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is a lifethreatening event and one of the important endpoints in clinical trials involving IPF. Despite this, there has been little evaluat...

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