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20:13 EDT 28th August 2016 | BioPortfolio

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Effect of Continued Treatment With Pirfenidone in IPF

Do idiopathic pulmonary fibrosis patients benefit from continued treatment with pirfenidone -- particularly those who experienced meaningful disease progression during treatment? Thorax

Acceptable tolerability found with pirfenidone for SSc-associated interstitial lung disease

Researchers found pirfenidone had an acceptable tolerability profile for the treatment of patients with systemic sclerosis-associated interstitial lung disease and suggested tolerability may improve w...

Kadmon Initiates Phase 2 Clinical Trial Evaluating KD025 in Idiopathic Pulmonary Fibrosis

NEW YORK, NY -- (Marketwired) -- 06/03/16 -- Kadmon Corporation, LLC today announced that the first patient has been dosed in a Phase 2 clinical trial of KD025, the Company's rho-associated coiled-co...

Prothena Announces Appointment of Chief Commercial Officer

DUBLIN, Ireland, Feb. 24, 2016 (GLOBE NEWSWIRE) -- Prothena Corporation plc (NASDAQ:PRTA), a late-stage clinical biotechnology company focused on the discovery, development and commercializatio...

Synairgen PLC and why the market is not the best arbiter of value

If the market worked as perfectly as its more rabid advocates insist, we wouldn’t have attractive anomalies such as Synairgen plc (LON:SNG). Its shares are trading at a fraction of what would be c...

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An Open-label, Phase II Study of the Safety and Tolerability of Pirfenidone in Patients with Scleroderma-associated Interstitial Lung Disease: the LOTUSS Trial.

Systemic sclerosis-associated interstitial lung disease (SSc-ILD) shares a number of clinical features and pathogenic mechanisms with idiopathic pulmonary fibrosis (IPF). This study was designed to ev...

A safety evaluation of pirfenidone for the treatment of idiopathic pulmonary fibrosis.

Pirfenidone is a novel oral anti-fibrotic agent approved for the treatment of idiopathic pulmonary fibrosis (IPF). Since IPF is a chronic and progressive disease most commonly encountered in an older ...

Not yet known side effects of pirfenidone in the treatment of idiopathic pulmonary fibrosis?

Pirfenidone Initiates a New Era in the Treatment of Idiopathic Pulmonary Fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal disease that has long eluded therapy. Prognosis remains very poor, and currently lung transplantation offers the only hope of s...

Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia.

Desmoplasia in human pancreatic cancer (PC) promotes cancer progression and hinders effective drug delivery. The objectives of this study were to characterize a homologous orthotopic model of PC in Sy...

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