Virulence Factors

Virulence factors are molecules expressed and secreted by pathogens (bacteria, viruses, fungi and protozoa) that enable them to achieve the following: * colonization of a niche in the host (this i...

Mylan wins final FDA approval for Itraconazole capsules ANDA

Mylan Pharmaceuticals has won final FDA approval for its abbreviated new drug application (ANDA) of Itraconazole capsules, 100mg, the generic version of Janssen Pharmaceutical's Sporanox capsules.

FDA approves Par Pharma fluvoxamine maleate ER capsules ANDA

The US Food and Drug Administration (FDA) has approved Par Pharmaceutical Companies' abbreviated new drug application (ANDA) for fluvoxamine maleate 100mg and 150mg extended-release (ER) capsules.

Zonegran Russian approval prompts Eisai's expansion in that market

Eisai (TYO: 4523), a leading Japanese drugmaker, says it plans to expand its operations into Russia, with the approval of its first product in this market - the epilepsy treatment, Zonegran (zonisamid...

Outside the Zonegran: Eisai gets EU monotherapy extension

Within days of publishing data that formed the basis of its marketing authorisation application (MAA), Eisai has received approval from the European Medicines Agency (EMA) extending the use of once-d...

Eisai's Zonegran monotherapy 'non-inferior' in epilepsy

Ahead of receiving a final decision from the European Medicines Agency (EMA) on the use of its antiepileptic agent, Zonegran (zonisamide), as a monotherapy, Eisai has published the Phase III data tha...

Raspberry Ketone Diet: Get A Free Bottle Of Raspberry Ketones

Raspberry ketone diet pills giveaway campaign just launched at http://raspberryketonespecial.com (PRWEB) September 27, 2012 Raspberry ketones "get a free bottle" campaign has been launched...

New Research on Eisai's Antiepileptic Drug Zonegran®(Zonisamide) Presented at European Congress on Epileptology (ECE)

New data on the novel anti-epileptic drug (AED) Zonegran® (zonisamide) is presented today at the 10th European Congress on Epileptology (ECE) in London. Since July 2012, zonisamide has been licens...

Epilepsy Treatment Zonegran® Gets License Extension Application Accepted By EMA

The European Medicines Agency (EMA) has accepted the submission by Eisai of an application to extend the use of adjunctive epilepsy treatment Zonegran® (zonisamide) in the treatment of partial seizur...

Interaction between Brush Layers of Bottle-Brush Polyelectrolytes: Molecular Dynamics Simulations.

Interactions between tethered layers composed of aggrecan (charged bottle-brush) macromolecules are responsible for the molecular origin of cartilage biomechanical behavior. To elucidate the role of t...

Highly fluorescent M(2)L(4) molecular capsules with anthracene shells.

M(2)L(4) molecular capsules self-assembled from M(ii) ions (where M = Zn, Ni, and Pd) and bent bidentate ligands constructed from anthracene fluorophores. The Ni(ii) and Zn(ii) capsules exhibited weak...

More on the Losses of Dissolved CO(2) during Champagne Serving: Toward a Multiparameter Modeling.

Pouring champagne into a glass is far from being inconsequential with regard to the dissolved CO(2) concentration found in champagne. Three distinct bottle types, namely, a magnum bottle, a standard b...

Gastrointestinal toxicity due to bitter bottle gourd (Lagenaria siceraria)─a report of 15 cases.

Traditional medicine is widely practiced in tropical countries. Bottle gourd (Lagenaria siceraria) fruit juice is advocated as a part of complementary and alternative medicine. If the bottle gourd jui...

A mechanistic model for the prediction of in-use moisture uptake by packaged dosage forms.

A mechanistic model for the prediction of in-use moisture uptake of solid dosage forms in bottles is developed. The model considers moisture transport into the bottle and moisture uptake by the dosage...