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phospho-CDC25c response dna damage drug Pages on BioPortfolio:

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Trans-activation of the DNA-damage signalling protein kinase Chk2 ...
The current model for Chk2 activation in response to DNA damage involves two ..... l) consisting of anti-phospho CDC25C (1.25 nM, #9528, Cell Signalling ...
http://www.nature.com/emboj/journal/v25/n13/full/7601209a.ht...

Trans-activation of the DNA-damage signalling protein kinase Chk2 ...
The role played by Chk2 in mediating the cellular response to DNA damage ..... of anti-phospho CDC25C (1.25 nM, #9528, Cell Signalling Technology Inc., MA, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=15...

Oncogene - Human T-cell leukemia virus type 1 Tax attenuates ...
In response to DNA damage, Chk1 and Chk2 phosphorylate p53, resulting in .... ( S20P) (Cell Signaling), and anti-phospho-Cdc25C (S216P) (Cell Signaling). ...
http://www.nature.com/onc/journal/v25/n3/full/1209059a.html...

Exposure of Human Lung Cancer Cells to 8-Chloro-Adenosine Induces ...
The membranes were probed with specific antibodies for phospho-Cdc25C ..... Iliakis G, Wang YA, Guan J, Wang H. DNA damage checkpoint control in cells ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=15...

Oncogene - Genetic disruption of the Nrf2 compromises cell-cycle ...
To test for DNA damage, we used fluorescein isothiocyanate ...... acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response ...
http://www.nature.com/onc/journal/vaop/ncurrent/full/onc2008...

p14ARF Activates a Tip60-Dependent and p53-Independent ATM/ATR/CHK ...
Recently, the exposure of cells with a chromatin-modifying drug was also ..... In response to DNA damage, these two proteins are rapidly phosphorylated at ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=14...

Oncogene - Genetic disruption of the Nrf2 compromises cell-cycle ...
Both N-acetylcysteine and glutathione (GSH) supplementation ablated the DNA lesions and DNA damageresponse pathways in Nrf2-/- cells; however only GSH ...
http://www.nature.com/onc/journal/v27/n44/full/onc2008188a.h...

Rereplication by Depletion of Geminin Is Seen Regardless of p53 ...
Cell lines and drugs. Human colorectal cancer cell lines HCT116 (p53/) and HCT116 .... In response to DNA damage, both Chk1 and Chk2 are activated in ATM
...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=47...

Trans-activation of the DNA-damage signalling protein kinase Chk2 ...
The role played by Chk2 in mediating the cellular response to DNA damage gives ...... l) consisting of anti-phospho CDC25C (1.25 nM, #9528, Cell Signalling ...
http://www.nature.com/emboj/journal/v25/n13/full/7601209a.ht...

76 selected items - PubMed Results
Although the Chk1-mediated cell growth arrest in response to DNA damage is .... suppressor to induce the accumulation of inactive phospho-Cdc25C(Ser216) ...
http://www.ncbi.nlm.nih.gov/pubmed/17110335,17097061,1680723...

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