Cell Death and Differentiation - ADAM10 regulates FasL cell ...
Proteolytic cleavage leads to the generation of membrane-bound N-terminal ..... the neuronal adhesion molecule L1.39 For some of these substrates, ADAM10 is ...
http://www.nature.com/cdd/journal/v14/n5/full/4402101a.html...
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A role for exosomes in the constitutive and stimulus-induced ...
ADAM10 was the predominant protease responsible for L1 and CD44 cleavage in exosomes ... activity of ADAM10 is due to substrate specificity for L1 and CD44,
...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=13...
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Journal of Investigative Dermatology - ADAM10 Is the Constitutive ...
30 Oct 2008 ... One inhibitor, namely GI254023X, preferentially blocks ADAM10 with a 100-fold higher specificity toward ADAM10 than to other proteases, ...
http://www.nature.com/jid/journal/vaop/ncurrent/full/jid2008...
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Substrate Specificity of γ-Secretase and Other Intramembrane Proteases
Reiss, K; Maretzky, T; Ludwig, A; Tousseyn, T; de Strooper, B; Hartmann, D; Saftig, P. ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion
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http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=25...
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RECK modulates Notch signaling during cortical neurogenesis by ...
To examine the specificity of the relationship between RECK and ADAM10 in ..... A novel proteolytic cleavage involved in Notch signaling: the role of the ...
http://www.nature.com/neuro/journal/v10/n7/full/nn1922.html...
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Evidence for Functional Redundancy Between C. elegans ADAM ...
Another is EGF precursor, which appears to be cleaved by ADAM10 in response to G -protein ..... We have provided evidence that two ADAM family proteases, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=18...
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Millipore - Product Detail
Involved in the cleavage of the adhesion molecule L1 at the cell surface and in ... Protein A Purified. Specificity:. Recognizes ADAM-10. Antibody Category: ...
http://www.millipore.com/catalogue/item/ab19026...
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PubMed Result
ADAM10 inhibition of human CD30 shedding increases specificity of targeted ... ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in ...
http://www.ncbi.nlm.nih.gov/pubmed/17072319,17389606,1512882...
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Kidney International - Characterization of CXCL16 and ADAM10 in ...
It is known that transmembrane CXCL16 can be cleaved by ADAM10, ... To prove that ADAM10 may also be the potential protease cleaving CXCL16 in tubular cells
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http://www.nature.com/ki/journal/v74/n3/full/ki2008181a.html...
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The Cleavage and Polyadenylation Specificity Factor in Xenopus ...
In some instances Complete-Mini (Boehringer Mannheim) protease inhibitor ...... and a cleavage/specificity factor required for pre-mRNA polyadenylation. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=84...
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