Akt And Medulloblastoma Pages on BioPortfolio:

BioPortfolio - Medulloblastoma
Medulloblastoma Patents: USPTO Logo. US Patent No. Title. 7582297, Methods of treating respiratory conditions. 7589068, Inhibitors of Akt activity ...
http://www.bioportfolio.com/indepth/Medulloblastoma.html...

BioPortfolio - CFLAR - CASP8 and FADD-like apoptosis regulator
14662022, Akt activity promotes human gastric cancer cell survival against ... Hedgehog signaling is aberrantly activated in glioma, medulloblastoma,. ...
http://www.bioportfolio.com/gene/8837-CFLAR.html...

BioPortfolio - GSK3B publications
17016438, Hypersensitivity of medulloblastoma cells in ... the sequential activation of Akt and GSK-3beta plays an important role directing hippocampal
...
http://www.bioportfolio.com/gene/2932-GSK3B/publications.htm...

BioPortfolio - integrin, beta-like 1 (with EGF-like repeat domains ...
Integrins mediate adhesion of medulloblastoma cells to tenascin ... Specific antibody for the gene product of AKT1, the protein v-akt-1 or Protein . ...
http://www.bioportfolio.com/antibody/integrin,_beta-like_1_(...

BioPortfolio - FRAP1 - FK506 binding protein 12-rapamycin ...
18048359, a key regulatory role of the Akt/mTOR pathway in the generation of ... development and medulloblastoma: separate regulation of mammalian target of ...
http://www.bioportfolio.com/gene/2475-FRAP1.html...

BioPortfolio - Cell Growth Processes - InDepth
... complex suppression in cerebellar development and medulloblastoma: separate ... Genetic alterations in the phosphoinositide 3-kinase/Akt signaling ...
http://www.bioportfolio.com/indepth/Cell_Growth_Processes.pd...

BioPortfolio - CTNNB1 publications
12209999, Role of Wnt pathway in medulloblastoma oncogenesis: ..... 3-kinase/Akt and beta-catenin/T-cell factor-dependent pathway in human endothelial cells ...
http://www.bioportfolio.com/gene/1499-CTNNB1/publications.ht...

BioPortfolio - NFKB1 publications
... altered beta1-integrin expression in medulloblastoma and ERK activation ...... Spontaneous apoptosis was associated with the loss of Akt and NF-kappaB
...
http://www.bioportfolio.com/gene/4790-NFKB1/publications.htm...

Results from other life science and pharmaceutical sites:

Phosphatidylinositol 3'-kinase/AKT signaling is activated in ...
EXPERIMENTAL DESIGN: To examine a role for PI3K/AKT signaling in the molecular pathogenesis of human medulloblastoma, we did an immunohistochemical study of
...
http://www.ncbi.nlm.nih.gov/pubmed/16707597...

Modeling Medulloblastoma With Genetically Engineered Mice ...
To demonstrate a functional role for PI3K signaling in medulloblastoma formation , we transferred an activated, transforming allele of Akt. We found that Akt ...
http://www.medscape.com/viewarticle/518159_9...

Activation of Akt and Erk pathways in medulloblastoma.
Activation of Akt and Erk pathways in medulloblastoma. Włodarski P, Grajkowska W , Łojek M, Rainko K, Jóźwiak J. Department of Histology and Embryology, ...
http://www.ncbi.nlm.nih.gov/pubmed/17039417...

Insulin-like Growth Factor 2 is Required for Progression to ...
1 Nov 2008 ... Medulloblastoma (MB) can arise in the cerebellum due to genetic activation of the ..... and phosphorylation of Igf pathway target Akt (Fig. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=25...

Targeting the PI3K p110alpha isoform inhibits medulloblastoma ...
PURPOSE: The phosphoinositide 3-kinase (PI3K)/Akt pathway is frequently activated in human cancer and plays a crucial role in medulloblastoma biology.
...
http://www.ncbi.nlm.nih.gov/pubmed/18980969...

Oncogene - Abstract of article: Linking DNA damage to ...
We observed a dramatic difference in medulloblastoma incidence, which ranged from ... increased activation of the cell survival-promoting Akt/Pkb protein,
...
http://www.nature.com/onc/journal/v25/n8/abs/1209032a.html...

How the Hedgehog Outfoxed the Crab: Interference with HEDGEHOG-GLI ...
Shh, Medulloblastoma, 138. Shh; Shh+cMyc, Medulloblastoma, 221. Shh; Shh+IGF2 ; Shh+Akt, Medulloblastoma, 222. SKIN. Tadpole, Somatic misexpression ...
http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&p...

Modeling Medulloblastoma With Genetically Engineered Mice: Germ ...
Germ Line Inactivation of the Patched Gene Causes Medulloblastoma: The author ... Serine/threonine phosphorylation of Akt at the plasma membrane by ...
http://www.medscape.com/viewarticle/518159_3...

Integrins mediate adhesion of medulloblastoma cells to tenascin ...
The Akt and MAPK pathways are mediators of the survival and proliferation of many disseminated cancers but their role in disseminated medulloblastoma has ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679155/...

Brain Cancer Stem Cells Display Preferential Sensitivity to Akt ...
Activation of Akt and Erk pathways in medulloblastoma. Folia Neuropathol. 2006; 44:214–220. [PubMed]. 18. Knobbe CB, Trampe-Kieslich A, Reifenberger G. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=27...

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