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AUT00063 develpoed by Autifony Therapeutics, is a novel, orally active small molecule designed to selectively modulate Kv3 potassium channels, which are important in central auditory processing. Pre...
Interleukin-1 (IL-1) beta is a proinflammatory cytokine driving joint inflammation as well as systemic signs of inflammation, such as fever and acute phase protein production. Current therapy targetin...
An emerging body of research reveals that past studies — some of which may form the basis of current policies and recommendations — cannot be replicated by investigators today.
Type: Brief CommunicationFor ophthalmic drug products, the determination of bioequivalence can be challenging, as drug concentrations at the site of action cannot always be measured. The FDA has recom...
Several observational studies support the hypothesis that statin use reduces the risk of advanced prostate cancer. In this Review, the authors discuss molecular mechanisms that might determine this ef...
Multiple BCG strains are used for intravesical instillation treatment of non-muscle-invasive bladder cancer but no large randomized studies comparing these strains are available. To enable creation of...
Lion Biotechnologies' three affiliated studies were resumed, but Kite's four studies remain suspended.
Spin-current-induced magnetization reversal of a perpendicularly magnetized thulium iron garnet film is reported. The spin current is driven by the current flowing through a Pt overlayer.
Soft drink studies conducted by independent researchers tend to draw different conclusions than studies supported by the beverage industry.
Genome-wide association studies (GWAS) have revealed over a dozen genetic factors robustly associated with the common forms of migraine. The identification of these factors, the implicated biological ...
Although rare, penile cancer carries high morbidity and mortality particularly when pertaining to the management of locally advanced and/or metastatic disease. The current scientific literature lacks ...
The purpose of the current review is to summarize recent behavior analytic research on problem behavior in individuals with intellectual disabilities. We have focused our review on studies published f...
The purpose of this review is to summarize current studies detailing the impact of unilateral sensorineural hearing loss in children and the most current modalities of treatment used in its management...
Shorter treatment regimens for tuberculosis (TB) are deemed vital for advancing TB control. Murine studies have suggested potential new regimens; however, Phase II human studies of these drug combinat...