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Search Results for "Bnppatr Peptide"

04:16 EDT 23rd August 2017 | BioPortfolio

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Natriuretic peptide rDNA

TASH Biotechnology

Shanghai TASH Biotechnology Co.,Ltd. specializes in peptide development on the basis of high technology. TASH Biotechnology are focusing on custom peptide synthesis, and the research, development...

Proteasome Inhibitors

The proteasome is involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune respon...

Pseudomonas aeruginosa Vaccines

Pseudomonas aeruginosa is an opportunistic gram-negative bacteria that lives in soil, water, and even in environments like hot tubs. For most healthy people, this bacteria seldom poses a problem. Pse...

Immunocytokines

Although the human cytokines interleukin-2 (IL-2) and tumor necrosis factor (TNF) alpha are approved marketed for tumor therapy, their use is rather limited due to severe systemic side effects. Targ...

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Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products

Peptide backbone N-methylation, as seen in cyclosporin A, has been considered to be exclusive to nonribosomal peptides. We have identified the first post-translationally modified peptide or protein ha...

Personalized peptide vaccines and their relation to other therapies in urological cancer

Kimura and colleagues describe the scientific background to the concept of personalized peptide vaccines and review clinical data on safety and efficacy of these treatments for urological cancers. The...

Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide

The trapping of antibodies in endosomes often limits their use for intracellular targeting. Now, a single amino acid substitution on a spider-venom peptide has been shown to attenuate the cell membran...

A protein that may have the potential to fight off frailty as we age

First full-length structure of GLP-1 receptor bound to peptide agonist

Heptares Therapeutics has published the first high-resolution X-ray crystal structure of the full-length glucagon-like peptide-1 (GLP-1) receptor bound to a peptide agonist.

Janssen Taps PeptiDream for Peptide Discovery Tech in Deal Worth up to $1.15bn

Janssen Pharmaceuticals and PeptiDream agreed a potentially $1.15 billion drug discovery collaboration that will hinge on the latter’s Peptide Discovery Platform System (PDPS) technology to find mac...

Janssen Taps PeptiDream for Peptide Discovery Tech in Deal Worth up to $1.15b

Janssen Pharmaceuticals and PeptiDream agreed a potentially $1.15 billion drug discovery collaboration that will hinge on the latter’s Peptide Discovery Platform System (PDPS) technology to find mac...

Peptide acts as mediator for learning

(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) In order to adapt to changes in the environment, the brain produces new nerve cells even at adult age. These young neurons are ...

Matching PubMed Articles

Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene.

Peptide assemblies have received significant attention because of their important role in biology and applications in bionanotechnology. Despite recent efforts to elucidate the principles of peptide s...

Synthesis and stabilities of peptide-based 1rotaxanes: molecular grafting onto lasso peptide scaffolds.

The chemical synthesis of peptide-based [1]rotaxanes (lasso peptides) was achieved by [2]rotaxane formation followed by two chemoselective ligation reactions. Our approach enabled incorporation of var...

An iterative glycosyltransferase EntS catalyzes transfer and extension of O- and S-linked monosaccharide in enterocin 96.

Glycosyltransferases are essential tools for in vitro-glycoengineering. Bacteria harbor an unexplored variety of protein glycosyltransferases. Here, we describe a peptide glycosyltransferase (EntS) en...

Crystal structure of the GLP-1 receptor bound to a peptide agonist.

Glucagon-like peptide 1 (GLP-1) regulates glucose homeostasis through the control of insulin release from the pancreas. GLP-1 peptide agonists are efficacious drugs for the treatment of diabetes. To g...

Peptide Specificity Analysis of Peptide:N-glycanases Using Synthetic Chitobiose-pentapeptides.

Peptide:N-glycanase is a deglycosylation enzyme releasing N-glycan from glycoproteins. Although glycan specificity analysis of this enzyme has been reported, recognition requirements for the peptide s...

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