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Search Results for "Chemerine Knockout Mice"

22:07 EDT 25th September 2016 | BioPortfolio

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CD30 Antibodies

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. It ...

Polo like kinase Plk 1

Polo-like kinase (Plk) is an important cell cycle regulatory kinase that has been implicated in a multitude of cell cycle events. Plks form a family of four different proteins that regulates many as...

Sphingosine 1 Phosphate S1P

Sphingosine-1-phospate (S1P) is a phospholipid released by platelets, mast and other cells. It is now known that S1P stimulates at least five different G-protein coupled receptors (GPCRs): S1P1, S1P2,...

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Mice with midbrain neuron-specific knockout of LIM homeobox transcription factor 1 α (LMX1A; LMX1) and LMX1B as a model of Parkinson's disease (PD)

LMX1A/LMX1B-knockout mice could be useful for screening therapies to treat PD.

ATP binding cassette subfamily A member 7 (ABCA7)-knockout mouse model of Alzheimer's disease (AD)

Mice with knockout of the

GLIS family zinc finger 3 (GLIS3)-knockout mice transgenically expressing chicken lysozyme (LYZ) as models of Type I and Type II diabetes

GLIS3-knockout mice transgenically expressing chicken

Patched domain containing 1 (PTCHD1)-knockout mouse model of attention deficit hyperactivity disorder (ADHD)

PTCHD1-knockout mice could be useful for screening therapies to help treat ADHD.

Generation of knockout mice by Cpf1-mediated gene targeting

Study unveils novel crosstalk mechanism between mitochondrial translation and cytoplasmic translation

(Chinese Academy of Sciences Headquarters) By using a systemic mtEF4 gene knockout mouse model, researchers from the Institute of Biophysics of the Chinese Academy of Sciences found that mtEF4 knockou...

Mice with knockout of interferon-related genes as models of Zika infection

Two mouse models with knockout of interferon-related genes could be useful for screening therapies to treat Zika infection.

Immune Defect Detected in Knockout Mice

Researchers have identified a mutation in a commonly used commercial mouse strain that could impact experimental results.

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Mup-knockout mice generated through CRISPR/Cas9-mediated deletion for use in urinary protein analysis.

Major urinary proteins (MUPs) are the most abundant protein species in mouse urine, accounting for more than 90% of total protein content. Twenty-one Mup genes and 21 pseudogenes are clustered in a re...

Mir-27a promotes apoptosis of cochlear sensory epithelium in Cx26 knockout mice.

To investigate the underlying molecular mechanism for connexin 26 (Cx26) knockout-induced apoptosis, we performed TUNEL assays to detect apoptosis in the cochlear sensory epithelium in Cx26 knockout m...

Phosphorylation of 4EBP by oral leucine administration was suppressed in the skeletal muscle of PGC-1α knockout mice.

Leucine is known to increase mTOR-mediated phosphorylation of 4EBP. In this study, leucine was administered to skeletal muscle-PGC-1α knockout mice. We observed attenuated 4EBP phosphorylation in the...

Probucol inhibits MMP-9 expression through regulating miR-497 in HUVECs and apoE knockout mice.

This study investigated the molecular mechanisms underlying the inhibition of MMP-9 expression by probucol, which is widely used for atherosclerotic prevention, in cultured human umbilical vein endoth...

Ficolins Promote Fungal Clearance in vivo and Modulate the Inflammatory Cytokine Response in Host Defense against Aspergillus fumigatus.

Aspergillus fumigatus is an opportunistic fungal pathogen that causes severe invasive infections in immunocompromised patients. Innate immunity plays a major role in protection against A. fumigatus. T...

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