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Search Results for "Chemerine Knockout Mice"

07:05 EDT 25th May 2016 | BioPortfolio

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CD30 Antibodies

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. It ...

Polo like kinase Plk 1

Polo-like kinase (Plk) is an important cell cycle regulatory kinase that has been implicated in a multitude of cell cycle events. Plks form a family of four different proteins that regulates many as...

Sphingosine 1 Phosphate S1P

Sphingosine-1-phospate (S1P) is a phospholipid released by platelets, mast and other cells. It is now known that S1P stimulates at least five different G-protein coupled receptors (GPCRs): S1P1, S1P2,...

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ATP binding cassette subfamily A member 7 (ABCA7)-knockout mouse model of Alzheimer's disease (AD)

Mice with knockout of the

GLIS family zinc finger 3 (GLIS3)-knockout mice transgenically expressing chicken lysozyme (LYZ) as models of Type I and Type II diabetes

GLIS3-knockout mice transgenically expressing chicken

Patched domain containing 1 (PTCHD1)-knockout mouse model of attention deficit hyperactivity disorder (ADHD)

PTCHD1-knockout mice could be useful for screening therapies to help treat ADHD.

Study unveils novel crosstalk mechanism between mitochondrial translation and cytoplasmic translation

(Chinese Academy of Sciences Headquarters) By using a systemic mtEF4 gene knockout mouse model, researchers from the Institute of Biophysics of the Chinese Academy of Sciences found that mtEF4 knockou...

Mice with knockout of interferon-related genes as models of Zika infection

Two mouse models with knockout of interferon-related genes could be useful for screening therapies to treat Zika infection.

Geminin coiled-coil domain containing (GMNC)-knockout mouse model of reduced generation of multiple motile cilia (RGMC) and other human ciliopathies

GMNC-knockout mice could be useful for screening therapies to treat reduced generation of multiple motile cilia (RGMC) and other human ciliopathies.

Immune Defect Detected in Knockout Mice

Researchers have identified a mutation in a commonly used commercial mouse strain that could impact experimental results.

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

FUS is an RNA-binding protein involved in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Cytoplasmic FUS-containing aggregates are often associated with concomitant loss of nuc...

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Mup-knockout mice generated through CRISPR/Cas9-mediated deletion for use in urinary protein analysis.

Major urinary proteins (MUPs) are the most abundant protein species in mouse urine, accounting for more than 90% of total protein content. Twenty-one Mup genes and 21 pseudogenes are clustered in a re...

IgG Suppresses Antibody Responses in Mice Lacking C1q, C3, Complement Receptors 1 and 2, or IgG Fc-Receptors.

Antigen-specific IgG antibodies, passively administered to mice or humans together with large particulate antigens like erythrocytes, can completely suppress the antibody response against the antigen....

Mir-27a promotes apoptosis of cochlear sensory epithelium in Cx26 knockout mice.

To investigate the underlying molecular mechanism for connexin 26 (Cx26) knockout-induced apoptosis, we performed TUNEL assays to detect apoptosis in the cochlear sensory epithelium in Cx26 knockout m...

The protective role of tacrine and donepezil in the retina of acetylcholinesterase knockout mice.

To determine the effect of different concentrations of the acetylcholinesterase (AChE) inhibitors tacrine and donepezil on retinal protection in AChE(+/-) mice (AChE knockout mice) of various ages.

Beta2-adrenergic activity modulates vascular tone regulation in Lecithin:Cholesterol Acyltransferase knockout mice.

Lecithin:cholesterol acyltransferase (LCAT) deficiency is associated with hypoalphalipoproteinemia, generally a predisposing factor for premature coronary heart disease. The evidence of accelerated at...

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