Search Results for "Chemerine Knockout Mice"

18:30 EDT 1st August 2014 | BioPortfolio

Original Source: Expression of human chemerin induces insulin resistance in the skeletal muscle but does not affect weight, lipid levels and atherosclerosis in LDL receptor knockout mice on high fat diet.

AbstractObjective. Chemerin is a recently discovered hepatoadipokine that regulates adipocyte differentiation as well as chemotaxis and activation of dendritic cells and macrophages. Chemerin was reported to modulate insulin sensitivity in adipocytes and skeletal muscle cells in vitro and to exacerbate glucose intolerance in several mouse models in vivo. In humans, chemerin was shown to be associated with multiple components of the metabolic syndrome including body mass index, triglycerides, HDL-cholesterol...

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Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout

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Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice.

Aldehyde reductase (AKR1A), a member of the aldo-keto reductase superfamily, is highly expressed in the liver and is involved in both the detoxification of carbonyl compounds and ascorbic acid biosynt...

Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice.

Previous studies demonstrated that L-Fabp knockout mice are more susceptible to LD induced gallstones because of altered hepatic cholesterol metabolism and increased canalicular cholesterol secretion....

Aberrant production of IL-13 by T cells promotes exocrinopathy in Id3 knockout mice.

Elevated levels of the cytokine IL-13 has been found to be associated with autoimmune diseases, including Sjögren's Syndrome. However, whether IL-13 plays a causative role in disease development is n...

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