Track topics on Twitter Track topics that are important to you
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. It ...
Polo-like kinase (Plk) is an important cell cycle regulatory kinase that has been implicated in a multitude of cell cycle events. Plks form a family of four different proteins that regulates many as...
Sphingosine-1-phospate (S1P) is a phospholipid released by platelets, mast and other cells. It is now known that S1P stimulates at least five different G-protein coupled receptors (GPCRs): S1P1, S1P2,...
Mice with knockout of the
GLIS3-knockout mice transgenically expressing chicken
PTCHD1-knockout mice could be useful for screening therapies to help treat ADHD.
(Chinese Academy of Sciences Headquarters) By using a systemic mtEF4 gene knockout mouse model, researchers from the Institute of Biophysics of the Chinese Academy of Sciences found that mtEF4 knockou...
GMNC-knockout mice could be useful for screening therapies to treat reduced generation of multiple motile cilia (RGMC) and other human ciliopathies.
LONDON, March 7, 2016 /PRNewswire/ -- Knockout mice models are of paramount importance in biomedical researches which focus on finding cure for human diseases. Extensive research on the knock-out mice...
TRPCs (Canonical Transient Receptor Potential Channels) are a group of non-selective cation channels that allow sodium and calcium into cells. There are seven different genes in mice that code TRPCs. ...
Major urinary proteins (MUPs) are the most abundant protein species in mouse urine, accounting for more than 90% of total protein content. Twenty-one Mup genes and 21 pseudogenes are clustered in a re...
Antigen-specific IgG antibodies, passively administered to mice or humans together with large particulate antigens like erythrocytes, can completely suppress the antibody response against the antigen....
To investigate the underlying molecular mechanism for connexin 26 (Cx26) knockout-induced apoptosis, we performed TUNEL assays to detect apoptosis in the cochlear sensory epithelium in Cx26 knockout m...
The renin-angiotensin system (RAS) plays a central role in blood pressure regulation. Although clinical and experimental studies have suggested that inhibition of RAS is associated with progression of...
To determine the effect of different concentrations of the acetylcholinesterase (AChE) inhibitors tacrine and donepezil on retinal protection in AChE(+/-) mice (AChE knockout mice) of various ages.