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cjc-1134 Pages on BioPortfolio:
Results from other life science and pharmaceutical sites:
Incretin Analogs Other Than Exenatide
CJC-1134-PC is a long-acting GLP-1 receptor agonist that is generated by ex vivo ... [10] To determine whether CJC-1134-PC could retain the same profile of ...
http://www.medscape.com/viewarticle/540919...
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An albumin-exendin-4 conjugate engages central and ...
METHODS: We studied the actions of CJC-1134-PC, a recombinant human serum albumin-exendin-4 conjugated protein, at the GLP-1R using heterologous cells ...
http://www.ncbi.nlm.nih.gov/pubmed/18313669...
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Non-linear enzymatic logic in natural product modular mega ...
(sanofi-aventis, phase II [652672]) and CJC-1134. (ConjuChem Biotechnologies Inc , phase I/II [664173]), as. well as the BIM-51077 back-up compound BIM-51182 ...
http://www.biomedcentral.com/content/pdf/cd-834214.pdf...
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Incretin Mimetics and DPP-IV Inhibitors for Type 2 Diabetes
However, further clinical development of CJC-1131 has been put on hold in favor of CJC-1134, an exendin-4 conjugate, according to 30 September 2005 and 25 ...
http://www.medscape.com/viewarticle/549509_3...
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Gene Result
mRNA levels of Gck, Glp1r, and Pdx1 were increased in pancreatic RNA from both CJC-1134-PC- and/or Ex-4-treated mice. ...
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDet...
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Table 1 : Non-insulin therapies for type 2 diabetes : Nature ...
CJC-1134-PC, Conjuchem, II, GLP1 analogue. AVE2268, Sanofi–Aventis, II, SGLT2 inhibitor. 189075, GlaxoSmithKline, II, SGLT2 inhibitor ...
http://www.nature.com/nrd/journal/v6/n10/fig_tab/nrd2420_T1....
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New Drug Class The incretin system: glucagon-like peptide-1 ...
exendin-4 (CJC-1134). 87. Similarly, recombinant albumin-. GLP-1 proteins have been developed that mimic the full. range of GLP-1 actions in preclinical ...
http://www.novonordisk.com/images/diabetes/Liraglutide/Druck...
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