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16:23 EDT 18th August 2017 | BioPortfolio

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US FDA gives thumbs up to Avastin and Herceptin biosimilars

Amgen and Mylan have both received recommendations for their versions of Roche’s monoclonal antibody blockbusters Avastin and Herceptin.

Pfizer’s biosimilar shows similarity to Avastin

US drug giant Pfizer has moved closer to market with its biosimilar version of Roche’s Avastin (bevacizumab).

96% cheaper, Avastin is just as effective as Eylea against eye disorder

A clinical trial has found that the oncology drug Avastin (bevacizumab) is about as effective as Eylea…

Smartphone-Based ELISA Developed for Blood Antigens

A novel high speed, lab-on-a-chip ELISA test for antigens in blood samples depends on a unique nonstick polymer coating that...

DiaSorin reaches $55.3M deal to acquire Siemens' ELISA business

DiaSorin has agreed to pay $55.3 million on a debt- and cash-free basis for Siemens Healthineers' microtiter-based ELISA immu -More- 

Pfizer Announces Positive Top-Line Results from Comparative Study for PF-06439535, a Potential Biosimilar to Avastin

NEW YORK–(BUSINESS WIRE)–Pfizer Inc. (NYSE:PFE) today announced that the REFLECTIONS B7391003 study, a comparative, confirmatory safety and efficacy study of PF-06439535 versus Avastin® (...

ELISA: How I Wonder What You Are

My phone’s email notification went off, and I rolled over in bed to look at the clock. Saturday, 5 am. Wonderful. Who would email me at that hour? It had to be my undergraduate research PI. I unlock...

Pfizer announces positive top-line results from the comparative REFLECTIONS B7391003 study for PF-06439535, a potential biosimilar to Avastin® (bevacizumab)

Pfizer Inc. (NYSE:PFE) has announced that the REFLECTIONS B7391003 study, a comparative, confirmatory safety and efficacy study of PF-06439535 versus Avastin®(1) (bevacizumab), met its primary object...

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Quality of bevacizumab (Avastin®) repacked in single-use glass vials for intravitreal administration.

Avastin® (bevacizumab) is an anti-vascular endothelial growth factor (VEGF) monoclonal antibody given as an off-label drug by intravitreal administration for treatment of ocular diseases. The drug's ...

ELISA for Monitoring Nerve Growth Factor.

Nerve growth factor (NGF), a neurotrophin critical to neuronal viability, has become a popular research focus for the treatment of neurodegenerative diseases. Enzyme-linked immunosorbent assays (ELISA...

No serological evidence for Zika virus infection and low specificity for anti-Zika virus ELISA in malaria positive individuals among pregnant women from Madagascar in 2010.

It was previously reported that a malaria infection may interfere with the specificity of a commercial ELISA test against Zika virus (ZIKV). We analyzed 1,216 plasma samples from healthy, pregnant wom...

Investigation of an N-Terminal Prohormone of Brain Natriuretic Peptide Point-of-Care ELISA in Clinically Normal Cats and Cats With Cardiac Disease.

N-terminal prohormone of brain natriuretic peptide (NT-proBNP) concentrations may be increased in cats with various cardiac disorders. The point-of-care (POC) ELISA assay uses the same biologic reagen...

Prokaryotic expression of a codon-optimized capsid gene from duck circovirus and its application to an indirect ELISA.

Duck circovirus (DuCV), as a causative agent of long-term immunosuppressive disease, has caused heavy damage to waterfowl breeding worldwide. In this study, the full-length Cap (capsid) gene of DuCV w...

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