ghrelin agonist Pages on BioPortfolio:

Further proof of concept for targeting ghrelin in the treatment of ...
In contrast to ghrelin, leptin inhibits food intake and has also been under the obesity spotlight. A leptin agonist has recently been shown to not only ...
http://www.bioportfolio.com/news/leaddiscovery_7.htm...

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Feeding response to ghrelin agonist and antagonist investigated Obesity ... Central administration of ghrelin preferentially enhances fat ingestion Obesity ...
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BioPortfolio - PharmaNet Development Group
Ghrelin agonist (TZP-101): safety, pharmacokinetics and pharmacodynamic evaluation in healthy volunteers: a phase I, first-in-human study. ...
http://www.bioportfolio.com/biocorporate/5457-PharmaNet_Deve...

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Feeding response to ghrelin agonist and antagonist investigated Obesity Pathogenesis NewsRxObesity via NewsEdge Corporation 2005 FEB 12NewsRxcom & NewsRxnet ...
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NewsRxObesity via NewsEdge Corporation : 2005 FEB 12 - (NewsRx.com & NewsRx.net) -- Scientists examine the feeding response to a ghrelin agonist and ...
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Failure of eating to trigger ghrelin reduction in obesity
Leptin agonists have created a storm of interest since this mediator is able to reduce ... Field-leaders currently believe that further reduction of ghrelin ...
http://www.bioportfolio.com/LeadDiscovery/PubMed-070206.htm...

Acute effect of L-796568, a novel beta 3-adrenergic receptor ...
... most promising target for obesity, ghrelin (Click here for dossier access). ... Recently, a second beta3-adrenoceptor agonist, L-796568, directed at the ...
http://www.bioportfolio.com/LeadDiscovery/PubMed-060220.htm...

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NewsRxObesity via NewsEdge Corporation 2005 FEB 12NewsRxcom & NewsRxnet Scientists examine the feeding response to a ghrelin agonist and antagonist in lean ...
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Potential of ghrelin receptor ligands in the treatment of ...
While this supports the use of ghrelin receptor agonists in the treatment of cardiovascular disease it urges caution in the use of ghrelin receptor ...
http://www.bioportfolio.com/news/DailyUpdates_19.htm...

Worldwide Market for the Clinical Management of Obesity, 2007-2015
5.2.4 Serotonin receptor agonists 5.2.5 Intestinal peptide compounds 5.2.6 Ghrelin-based vaccine 5.3 Genetic Therapy. Section 6: Market Assessment ...
http://www.bioportfolio.com/cgi-bin/acatalog/info_306.html...

Results from other life science and pharmaceutical sites:

Ghrelin and PYY: Rising Stars in Appetite Regulation
To explore this concept further, the investigators measured substrate utilization in response to an oral ghrelin agonist. While feeding, the animals ...
http://www.medscape.com/viewarticle/459764...

Ghrelin agonist (TZP-101): safety, pharmacokinetic...[J Clin ...
Ghrelin agonist (TZP-101): safety, pharmacokinetics and pharmacodynamic evaluation in healthy volunteers: a phase I, first-in-human study. ...
http://www.ncbi.nlm.nih.gov/pubmed/18199894...

Elixir Pharmaceuticals Announces Ghrelin Agonist Data Presentation ...
(BUSINESS WIRE)--Elixir Pharmaceuticals, Inc., today announced that results from in-vivo preclinical studies with the Company’s ghrelin agonist, EX-1314, ...
http://www.biospace.com/news_story.aspx?NewsEntityId=100732...

Obesity - Obese Subjects Respond to the Stimulatory Effect of the ...
Obese Subjects Respond to the Stimulatory Effect of the Ghrelin Agonist Growth Hormone-Releasing Peptide-2 on Food Intake*. Blandine Laferrère*, Allison B. ...
http://www.nature.com/oby/journal/v14/n6/full/oby2006121a.ht...

Anti-inflammatory effect of the ghrelin agonist gr...[Am J Physiol ...
The aim of this work was to examine the effect of administration of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) to arthritic rats. ...
http://www.ncbi.nlm.nih.gov/pubmed/15507538...

Tranzyme Pharma Receives FDA Fast Track Designation for its Novel ...
Tranzyme Pharma Receives FDA Fast Track Designation for its Novel Ghrelin Agonist, TZP-101, for the Treatment of Severe Gastroparesis 7/12/2007 ...
http://www.biospace.com/news_story.aspx?NewsEntityId=62855...

Feeding response to ghrelin agonist and antagonist...[Life Sci ...
We also tested the feeding response of both groups to intra-peritoneal (I.P.) injection of ghrelin agonist and antagonist. Obese rats ate significantly more ...
http://www.ncbi.nlm.nih.gov/pubmed/15530508...

Table 1 : Patent Watch : Nature Reviews Drug Discovery
JP 2007532495, Gastrotech Pharma, Describes the use of a ghrelin agonist for treating weight loss, cachexia, disrupted sleep pattern and pathological ...
http://www.nature.com/nrd/journal/v7/n3/fig_tab/nrd2548_T1.h...

Ghrelin agonist (TZP-101): safety, pharmacokinetic...[J Clin ...
PubMed is a service of the US National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for ...
http://www.ncbi.nlm.nih.gov/pubmed/18199894/...

Æterna Zentaris Inc
Ghrelin agonists and antagonists hold considerable therapeutic potential in ... Hexarelin is a reference ghrelin agonist substance which stimulates food ...
http://www.aeterna.com/en/page.php?p=32&prod=28...

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