Trends in Neurosciences - Squelching glioblastoma stem cells by ...
Our study provides insight into different mechanisms of action of this class of drugs in recurrent glioblastoma patients and suggests that the timing of ...
http://www.cell.com/trends/neurosciences/abstract/S0166-2236...
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Intracranial inhibition of platelet-derived growth factor-mediated ...
Glioblastoma multiforme is the most common primary human brain tumor, and it is, ... to adjuvant therapies (radiation and chemicals), the mode of action of which is cytotoxic. ... class may have therapeutic potential for glioblastomas. ...
http://www.ncbi.nlm.nih.gov/pubmed/11016641...
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Control of human glioma cell growth, migration and invasion in ...
The data presented show that TGF-beta 1 exerts a growth-inhibitory action on both ... A human glioma cell line retaining expression of GFAP and gangliosides, ... New class of transforming growth factors potentiated by epidermal growth ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=20...
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A pilot clinical study of Δ9-tetrahydrocannabinol in patients with ...
We also evaluated THC action on the length of survival and various ... Keywords: cannabinoid, glioblastoma multiforme, pilot clinical study, antitumoral drug ... is glioblastoma multiforme (grade IV astrocytoma), the most frequent class ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360617/...
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Suramin and radiotherapy in newly diagnosed glioblastoma: Phase 2 ...
Suramin is an investigational agent with preclinical efficacy in a number of tumor types, including glioma, with the mechanism of action related to ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artinsti...
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Growth inhibition of glioblastoma cells by human Pur(alpha).
... alternating three basic aromatic class I and two acidic leucine-rich class II repeats in ... of Pur(alpha) which participate in growth inhibitory action of Pur(alpha). ... Glioblastoma cells treated with Tat-Pur(alpha) (109-131) and ...
http://www.ncbi.nlm.nih.gov/pubmed/11748591...
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Expression of murine interleukin 7 in a murine glioma cell line ...
Secretion of IL-7 from glioma cells did not result in morphology or growth .... I. Therapeutic action of TNF against an established murine sarcoma is indirect, ... Jay G. Role of the major histocompatibility complex class I antigens in tumor ... Fontana A, Hengartner H, de Tribolet N, Weber E. Glioblastoma cells ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=52...
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Activation of neuromedin B-preferring bombesin receptors on rat ...
These results demonstrate that the rat glioblastoma cell line C-6 possesses ... prove useful in exploring further the cellular basis of action of the peptides ..... Desmethionine alkylamide bombesin analogues: a new class of bombesin ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1132948/...
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PDGF-C Induces Maturation of Blood Vessels in a Model of ...
23 Feb 2009 ... Glioblastoma Multiforme (GBM) is a uniformly fatal tumor afflicting ..... Heldin CH, Westermark B. Mechanism of action and in vivo role of ... by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=26...
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Medical Management of Glioblastoma Multiforme: Temozolomide
Temozolomide: Chemotherapy in glioblastoma multiforme was once controversial and ... Mechanisms of Action. Temozolomide is an orally administered alkylating agent of the imidazotetrazine class that is chemically related to dacarbazine. ...
http://www.medscape.com/viewarticle/540151_2...
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