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19:15 EDT 2nd May 2016 | BioPortfolio

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Hydrocodone bitartrate ER regulatory update

Zohydro (Hydrocodone Bitartrate) for the Treatment of Chronic Pain

Zohydro (hydrocodone) is a single-entity oral drug indicated for the treatment of chronic pain. San Diego-based pharmaceutical company Zogenix developed and commercialised the drug in the US.

Prescriptions for hydrocodone plummet after US tightens prescribing rules

Prescriptions for combination analgesics containing the opiate hydrocodone have fallen by 22% since the US government imposed tougher prescribing rules in 2014, a study has found.1 Hydrocodone...

PharMEDium Services Recalls 4 mg Norepinephrine Bitartrate

NewsPharMEDium Services, LLC is voluntarily recalling 29 lots of 4 mg Norepinephrine Bitartrate (16 mcg/mL).Contributed Author: 

4mg Norepinephrine Bitartrate (16mcg/mL) Added to 0.9% Sodium Chloride in 250mL Viaflex Bag and 8mg Norepinephrine Bitartrate (32mcg/mL) Added to 0.9% Sodium Chloride in 250mL Viaflex Bag by Pharmedium: Recall - Discoloration

[Posted 12/31/2015] AUDIENCE: Pharmacy, Critical Care Medicine ISSUE: PharMEDium Services, LLC is voluntarily recalling 29 lots of 4mg Norepinephrine Bitartrate (16mcg/mL) added to 0.9% Sodium Chlorid...

Abrupt Dip in Hydrocodone Prescriptions After Rescheduling

Primary care doctors and surgeons account for most of the change in prescription of hydrocodone combination products, new data suggest. Medscape Medical News

Egalet ends partnership with Shionogi to develop hydrocodone drug candidate

US biotech firm Egalet Corp said it has gained worldwide rights to the hydrocodone drug candidate following…

FDA OKs hydrocodone immunoassay from Thermo Fisher

An immunoassay developed by Thermo Fisher Scientific has obtained 510(k) clearance from the FDA to detect hydrocodone, a freq -More- 

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Single-dose pharmacokinetics of 2 or 3 tablets of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) under fed and fasted conditions: two randomized open-label trials.

Biphasic immediate-release (IR)/extended-release (ER) hydrocodone bitartrate (HB)/acetaminophen (APAP) 7.5/325-mg tablets are formulated with gastroretentive ER drug delivery technology that has been ...

A pharmacokinetic evaluation of single and multiple doses of extended-release hydrocodone bitartrate in subjects experiencing surgical or osteoarthritic pain.

To assess the single-dose and steady-state pharmacokinetics of a single-entity hydrocodone extended-release (ER) formulation in patients enrolled in two separate phase 2 clinical studies.

Pharmacokinetic Profile and Sustained 24-hour Analgesia of a Once-daily Hydrocodone Bitartrate Extended-release Tablet with Abuse-deterrent Properties.

The purpose of this study was to evaluate the pharmacokinetics (PK) and 24-hour analgesic effectiveness of once-daily, single-entity, extended-release hydrocodone (HYD) with abuse-deterrent properties...

Relationship between change in pain intensity and functional outcomes in patients with chronic pain receiving twice daily extended-release hydrocodone bitartrate.

Evaluate levels of pain relief achieved in patients with chronic pain treated with hydrocodone-extended release (HC-ER) up to 48 weeks and show that these levels were associated with secondary functio...

Clinical efficacy of hydrocodone-acetaminophen and tramadol for control of postoperative pain in dogs following tibial plateau leveling osteotomy.

OBJECTIVE To evaluate clinical efficacy of hydrocodone-acetaminophen and tramadol for treatment of postoperative pain in dogs undergoing tibial plateau leveling osteotomy (TPLO). ANIMALS 50 client-own...

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