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Linking Cytotoxic Agents To Monoclonal Antibodies Service Contracts Pages on BioPortfolio:
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BioPortfolio - Pharmexa
Coordinated interactions between helper and cytotoxic T-lymphocytes (HTL. ... A focus on "engineered" antibodies Monoclonal Antibodies: Pipeline Analysis and
Competitive ... 7097837, Synthetic vaccine agents. →View more Pharmexa patents.
... This page has been viewed 456 times since April 2007, the link to the ...
http://www.bioportfolio.com/biocorporate/26141-Pharmexa.html...
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BioPortfolio - Imidazoline Receptors
Generation and characterization of novel human IRAS monoclonal antibodies. ... Reportlinker Adds Ion Channel Modulator Pipelines: Targets and Agents in
Development ... Link Between Two-Gene Interaction In Cancer May Offer Improved
Treatment ... Correlation Between Natural Cytotoxicity Receptors and
Intracellular ...
http://www.bioportfolio.com/indepth/Imidazoline_Receptors.ht...
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Datamonitor Pharmaceutical and Biotechnology Reports
Commercial Insight: Antipsychotics - Revenues of depots and new agents will ..... RNA therapy: the next big thing after monoclonal antibodies? ....
Commercial Insight: Cytotoxic Therapy Cancer Brands - Looming patent expiries
limit ..... In the longer term, with a strong genetic link and reliable
diagnostic test, ...
http://www.bioportfolio.com/cgi-bin/acatalog/Datamonitor.htm...
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BioPortfolio - Kyowa Hakko Kogyo Co Limited - Profile
18 Feb 2009 ... 2009 Feb;113(3-5):195-201. Epub 2008 Dec 30. (DOI Direct Link) ... OBJECTIVE: Antibody-dependent cellular cytotoxicity mediated by natural...8th April, 2009
.... 7332522- Liver function protecting or ameliorating agent ... 7241568- Anti-
fibroblast growth factor-8 monoclonal antibody ...
http://www.bioportfolio.com/biocorporate/6223-Kyowa%25252525...
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BioPortfolio - Menarini - Profile
Delimotecan (MEN 4901/T-0128) is a new cytotoxic prodrug constituted by a...6th November, ... Menarini Manufacturing, Logistics and Services Srl, via Sette
Santi 3,- J Mass Spectrom. ... Forces determining the adsorption of a monoclonal
antibody onto an .... 5670534- Distamycin a derivatives as anti-malarial agents
...
http://www.bioportfolio.com/biocorporate/6932-Menarini.pdf...
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BioPortfolio - XRCC1 - X-ray repair complementing defective repair ...
Publication Link, Summary of findings ... Increase the cisplatin cytotoxicity and cisplatin-induced DNA damage in HepG2 cells by XRCC1 ... 6753158, Assays,
agents, therapy and diagnosis relating to modulation of cellular DNA repair
activity ... XRCC1 (4i246) Antibody sc-73277 mouse monoclonal IgG2b, 50 µg/ 0.5
ml; ...
http://www.bioportfolio.com/gene/7515-XRCC1.html...
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BioPortfolio - TRADD - TNFRSF1A-associated via death domain
Publication Link, Summary of findings ... 12446787, chemotherapeutic drugs exhibited their cytotoxic effects in part by down-regulating Akt ...
identification of components of mammalian biochemical networks as targets for
therapeutic agents ... TRADD antibodies. ... TRADD antibody [18A11]. IHC-P.
Mouse monoclonal. ...
http://www.bioportfolio.com/gene/8717-TRADD.html...
| Results from other life science and pharmaceutical sites:
Applications of Glycosyltransferases in the Site-specific ...
General Utility of the Technique of Linking via Glycan Residue ... Keywords: Bioconjugation via glycan residues, MRI agents, cytotoxic agents, .... The
monoclonal antibodies whose N-linked glycan moieties have been modified with the
... National Cancer Institute, National Institutes of Health, under contract No.
...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291282/...
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Cytotoxic agents directed to peptide hormone receptors: Defining ...
... such as the development of neutralizing antibodies (3), have limited the ..... Linking Ell directly to 7G via a urea linker (Ell-CO-7G), resulted in an
agent that ... respect to the level of CCKBR expression, although they are
monoclonal. ... Human Services, under contract with Advanced BioScience
Laboratories. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=21...
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Site-Specific Linking of Biomolecules via Glycan Residues Using ...
Monoclonal antibodies (mAb) have one conserved N-linked oligosaccharide chain at the Asn297 ... they provide a means to target cytotoxic drugs, toxins,
radionuclides, .... can next be coupled with the orthogonal reactive coupling
agents. .... Cancer Institute, National Institutes of Health, under contract No.
...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435414/...
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Novel Human IGF-I-Specific And IGF-I, IGF-II Cross-Reactive ...
16 Apr 2009 ... Monoclonal antibody-based therapies have taken a lead among the new ... Agents that inhibit IGF1R expression or function can potentially block ... Fully human
antibodies reduce the probability for immune responses and cytotoxic side
effects ... TTC maintains an e-mail service to notify you of new ...
http://ttc.nci.nih.gov/opportunities/opportunity.php?opp_id=...
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History of cancer chemotherapy - Wikipedia, the free encyclopedia
A second group with an NCI contract, led by John Montgomery at the Southern ... Unlike so many other anti-cancer agents, this pharmaceutical was no accident.
... Although monoclonal antibodies (immune proteins which can be selected to ...
Conventional cytotoxic chemotherapy has shown the ability to cure some ...
http://en.wikipedia.org/wiki/History_of_cancer_chemotherapy...
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Human Monoclonal Antibody Against Mesothelin - Technology Transfer ...
28 Apr 2008 ... Additionally, the antibody may be used as a research agent for the detection of ... TTC maintains an e-mail service to notify you of new ...
http://ttc.nci.nih.gov/opportunities/opportunity.php?opp_id=...
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Roche Annual Report 2008 - Pharmaceuticals
23 Jan 2009 ... by the National Health Service. ... market, characterised by heavily discounted contract ..... R3502) is a novel antibody–drug conjugate linking trastuzumab (
the active ingredient of Herceptin) and the cytotoxic agent DM1. By targeting
the HER2 ... monoclonal antibody being developed by Roche, ...
http://www.roche.com/gb08e04.pdf...
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Autophagy Facilitates the Development of Breast Cancer Resistance ...
In contrast to either agent alone, Tzb and autophagy LC3 gene-siRNA .... Mouse anti-SQSTM1/p62 monoclonal antibody was purchased from Abcam plc. .... is the
recipient of a “Sara Borrell” post-doctoral contract (CD08/00283, ..... Role of
autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708925/...
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Therapeutics - Technology Transfer Center
26 Aug 2009 ... Imaging Agents to Monitor the Distribution of Therapies Delivered to the Brain ... Human and Improved Murine Monoclonal Antibodies Against CD22 .... TTC
maintains an e-mail service to notify you of new Collaborative Opportunities.
... of Health and Human Services] · [Link to the First Gov web site]
http://ttc.nci.nih.gov/opportunities/opportunities.php?cat_i...
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Induction of Tumor-specific T Cell Immunity by Anti-DR5 Antibody ...
Induction of perforin- and FasL-mediated T cell cytotoxicity that can ... cross- linking of DR5 by MD5-1 was sufficient to cause caspase-dependent tumor cell
death in vitro. .... National Institutes of Health, under contract number N01-C0
-12400. .... IgG2a monoclonal antibodies inhibit human tumor growth through ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211825/...
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