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Maytansine Solubility Pages on BioPortfolio:

BioPortfolio - ImmunoGen
Semisynthetic maytansine analogues for the targeted treatment of cancer. ... service contracts | immunogen email contact | maytansine solubility | immunogen
...
http://www.bioportfolio.com/biocorporate/5298-ImmunoGen.html...

Results from other life science and pharmaceutical sites:

Anti-microtubule activity of tubeimoside I and its colchicine ...
Analysis of soluble and polymerized tubulin by immunoblotting ..... the vinca alkaloids vinblastine and vincristine, rhizoxin, maytansine, combretastatin A4
...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493533/...

Therapeutic anticancer efficacy of a synthetic diazonamide analog ...
... solubility, bioavailability, activity against resistant cell populations, ... antitubulin drugs (vinblastine, maytansine, paclitaxel, and vincristine).
...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=17...

cd-562698 Paper alert Paper alert Damia G Daneshtalab M Elices MJ ...
This compound had a log p value of 4.9 and water solubility of > 10 mg/ml. .... 1-oxopropyl)-maytansine against CD56+ multiple myeloma cells. ...
http://www.biomedcentral.com/content/download/xml/cd-562698....

Novel Anti-Tubulin Cytotoxic Agents for Breast Cancer: Abstract ...
2 Apr 2009 ... This primarily results from poor solubility and the need to dissolve in solvents , ..... Maytansine. Cancer Treat. Rev. 5199–207 (1978). ...
http://www.medscape.com/viewarticle/587648...

ACTA MEDICA (HRADEC KRÁLOVÉ)
is the low solubility of taxol in water, thus, this drug must .... biotic produced by Penicillium griseofulvum, maytansine, ...
http://www.lfhk.cuni.cz/Data/files/Casopisy/1999/!AM199.PDF...

APPENDIX J
Maytansine. Mazindol. Mec. Meclizine dihydrochloride. Meclizine hydrochloride ...... Solubility A term expressing the percentage of a material (by weight) ...
http://www.lifespan.org/research/biohazard/docs/biohazardfor...

Synthesis and Structure-Activity Relationship Studies on ...
or maytansine-rhizoxin.13 Tryprostatin A 1 inhibited microtubule assembly by interfering with ... (iii) marginal oral bioavailability and poor solubility,
...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435077/...

ChemCruz™ Biochemicals
Because of its limited aqueous solubility and high serum binding ...... A binds to tubulin at a site overlapping that of vinblastine and maytansine. ...
http://www.scbt.com/chapter_chemicals.html...

LRSPL - National Institutes of Health (NIH) - Home Page
... E0039147|maitansine|maytansine| E0039148|mayapple|may apple| ...... disease| E0420996|soluble tumour necrosis factor receptor|soluble tumor necrosis ...
http://lexsrv3.nlm.nih.gov/SPECIALIST/Projects/lexicon/2004/...

ChemCruz™ Laborchemikalien
Drug solubility in water is greatly enhanced by complexing with HBC. ...... A binds to tubulin at a site overlapping that of vinblastine and maytansine. ...
http://www.scbt.com/de/chapter_chemicals.html...

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